Abstract: A vascular repair device includes a tubular graft body and a structural framework having at least two stents. A first stent of the stents is connected to the tubular graft body along an entirety of the first stent and a second of the stents includes a periodically changing shape that defines proximal apices having a first radii of curvature and distal apices having a second radii of curvature that is less than the first radii of curvature. The second stent is connected to the tubular graft body at the distal apices.

Abstract: A method for automatic endovascular alignment of a prosthesis includes loading the prosthesis in a distal delivery assembly, positioning a guidewire into a curved implantation site, and threading a guidewire lumen over the guidewire with the delivery assembly and into an implantation site to at least approximately align the curved distal portion to a curve of a curved implantation site and, thereby aligning the prosthesis.

Abstract: A method for automatic endovascular alignment of a prosthesis includes loading the prosthesis in a distal delivery assembly, positioning a guidewire into a curved implantation site, and threading a guidewire lumen over the guidewire with the delivery assembly and into an implantation site to at least approximately align the curved distal portion to a curve of a curved implantation site and, thereby aligning the prosthesis.

Abstract: A vascular repair device includes a tubular graft body and a structural framework having at least two stents. A first stent of the stents is connected to the tubular graft body along an entirety of the first stent and a second of the stents includes a periodically changing shape that defines proximal apices having a first radii of curvature and distal apices having a second radii of curvature that is less than the first radii of curvature. The second stent is connected to the tubular graft body at the distal apices.

Abstract: A delivery system for delivering and deploying a stent graft includes a guidewire catheter, an apex release catheter, an apex capture device, a relatively rigid, hollow catheter, and a distal nose. The apex capture device includes a distal capture portion fixedly connected to the distal end of the guidewire catheter and having a distal portion and a proximal stopper having an exposed side facing distally in a plane approximately perpendicular to a longitudinal axis of the guidewire catheter. The apex capture device also includes a proximal capture portion fixedly connected to the distal end of the apex release catheter and has fingers extending toward the distal capture portion in a distal direction that define an interior cavity to receive the proximal stopper. The proximal and distal capture portions of the apex capture device define a stent capture state.

Abstract: A vascular repair device includes a tubular graft body and a structural framework having at least two stents. A first stent of the stents is connected to the tubular graft body along an entirety of the first stent and a second of the stents includes a periodically changing shape that defines proximal apices having a first radii of curvature and distal apices having a second radii of curvature that is less than the first radii of curvature. The second stent is connected to the tubular graft body at the distal apices.

Abstract: A delivery system for delivering and deploying stent grafts having a proximal stent includes a first lumen and a stent capture device including a capture portion fixedly connected adjacent a first lumen distal end. An outer catheter has a catheter distal end and a catheter inner diameter. A second lumen having a second distal end is slidably disposed about the first lumen and within the outer catheter. A stent graft sheath has a sheath proximal end connected to the second distal end and disposed about the first lumen. The sheath has a sheath distal end and a sheath inner diameter greater than the catheter inner diameter for holding a compressed stent graft. A distal nose cone has a cone proximal end connected to either the capture portion or the first distal end. The nose cone and the capture portion are movably adjustable to selectively capture the sheath distal end therebetween.

Abstract: A method for implanting a prosthesis centrally within a curved lumen includes loading a prosthesis into a delivery sheath, advancing the sheath in a patient towards the curved lumen to place at least the proximal end of the prosthesis within the curved lumen, and centering the proximal end of the prosthesis and/or the distal end of the sheath within the curved lumen. In a first advancing step, the outer catheter containing the inner sheath is advanced together towards the curved lumen to a location proximal of the curved lumen and, in a second advancing step, the inner sheath containing the prosthesis is advanced into the curved lumen to place at least the proximal end within the curved lumen while the outer catheter substantially remains at the location. After centering, the proximal end of the prosthesis is deployed centered within the curved lumen.

Abstract: A system for implanting a prosthesis includes a prosthesis delivery device having a handle, an inner lumen, a nose cone, an intermediate lumen, a prosthesis sheath at the distal end of the intermediate lumen for holding therein a prosthesis to be implanted, and an outer lumen fixedly connected to the handle. The system can include a lumen control assembly operable to move the intermediate lumen with the prosthesis sheath between a retracted position and an extended position.

Abstract: A delivery system for delivering and deploying a stent graft includes a guidewire catheter, an apex release catheter, an apex capture device, a relatively rigid, hollow catheter, and a distal nose. The apex capture device includes a distal capture portion fixedly connected to the distal end of the guidewire catheter and having a distal portion and a proximal stopper having an exposed side facing distally in a plane approximately perpendicular to a longitudinal axis of the guidewire catheter. The apex capture device also includes a proximal capture portion fixedly connected to the distal end of the apex release catheter and has fingers extending toward the distal capture portion in a distal direction that define an interior cavity to receive the proximal stopper. The proximal and distal capture portions of the apex capture device define a stent capture state.

Abstract: A delivery system for delivering and deploying a stent graft includes a guidewire catheter, an apex release catheter, an apex capture device, a relatively rigid, hollow catheter, and a distal nose. The apex capture device includes a distal capture portion fixedly connected to the distal end of the guidewire catheter and having a distal portion and a proximal stopper having an exposed side facing distally in a plane approximately perpendicular to a longitudinal axis of the guidewire catheter. The apex capture device also includes a proximal capture portion fixedly connected to the distal end of the apex release catheter and has fingers extending toward the distal capture portion in a distal direction that define an interior cavity to receive the proximal stopper. The proximal and distal capture portions of the apex capture device define a stent capture state.

Abstract: A delivery system for delivering and deploying a stent graft includes a curved guidewire catheter, an apex release catheter, an apex capture device, a relatively rigid, hollow catheter, and a distal nose. The apex capture device includes a distal capture portion fixedly connected to the distal end of the guidewire catheter and having a distal portion and a proximal stopper having an exposed side facing distally in a plane approximately perpendicular to a longitudinal axis of the curved guidewire catheter. The apex capture device also includes a proximal capture portion fixedly connected to the distal end of the apex release catheter and has fingers extending toward the distal capture portion in a distal direction that define an interior cavity to receive the proximal stopper. The proximal and distal capture portions of the apex capture device define a stent capture state.

Abstract: A delivery system for endovascularly delivering a prosthesis along a guidewire to a curved implantation site includes a delivery device having control handle and an inner lumen slidably disposed in the handle between a retracted position and an extended position. The inner lumen has a distal end and a tip at the distal end of the inner lumen. An intermediate lumen is slidably disposed about the inner lumen and has a distal end. A relatively flexible prosthesis sheath is connected to the distal end of the intermediate lumen and a relatively stiff outer lumen is axially fixedly connected to the handle about the intermediate lumen. The outer lumen has a length only long enough to be inserted in a patient's aorta no further than the patient's celiac axis.

Abstract: A vascular repair device includes a tubular graft body and a structural framework having at least two stents. A first stent of the stents is connected to the tubular graft body along an entirety of the first stent and a second of the stents includes a periodically changing shape that defines proximal apices having a first radii of curvature and distal apices having a second radii of curvature that is less than the first radii of curvature. The second stent is connected to the tubular graft body at the distal apices.

Abstract: A delivery system for delivering and deploying a stent graft includes a curved guidewire catheter, an apex release catheter, an apex capture device, a relatively rigid, hollow catheter, and a distal nose. The apex capture device includes a distal capture portion fixedly connected to the distal end of the guidewire catheter and having a distal portion and a proximal stopper having an exposed side facing distally in a plane approximately perpendicular to a longitudinal axis of the curved guidewire catheter. The apex capture device also includes a proximal capture portion fixedly connected to the distal end of the apex release catheter and has fingers extending toward the distal capture portion in a distal direction that define an interior cavity to receive the proximal stopper. The proximal and distal capture portions of the apex capture device define a stent capture state.

Abstract: A method for implanting a prosthesis centrally within a curved lumen includes loading a prosthesis into a delivery sheath, advancing the sheath in a patient towards the curved lumen to place at least the proximal end of the prosthesis within the curved lumen, and centering the proximal end of the prosthesis and/or the distal end of the sheath within the curved lumen. In a first advancing step, the outer catheter containing the inner sheath is advanced together towards the curved lumen to a location proximal of the curved lumen and, in a second advancing step, the inner sheath containing the prosthesis is advanced into the curved lumen to place at least the proximal end within the curved lumen while the outer catheter substantially remains at the location. After centering, the proximal end of the prosthesis is deployed centered within the curved lumen.

Abstract: An apex capture device for holding proximal apices of a stent to be implanted includes a distal capture portion to be fixedly connected to a distal end of a first hollow lumen and a proximal capture portion fixedly connected to a distal end of a second hollow lumen. The distal capture portion has a longitudinal axis, a distal portion with a proximal end, and a proximal stopper having a distal side and a proximal side. At least a portion of the proximal side of the proximal stopper extends along a line that intersects a hollow first lumen. The proximal capture portion has fingers that define an interior cavity shaped to receive the proximal stopper.

Abstract: A delivery system for delivering and deploying a stent graft includes a guidewire catheter, an apex release catheter, an apex capture device, a relatively rigid, hollow catheter, a sheath catheter, a relatively flexible, hollow stent graft sheath and a distal nose. The apex capture device includes a distal capture portion fixedly connected to the distal end of the guidewire catheter and having a distal portion and a proximal stopper having an exposed side facing distally in a plane approximately perpendicular to a longitudinal axis of the guidewire catheter. The apex capture device also includes a proximal capture portion fixedly connected to the distal end of the apex release catheter and has fingers extending toward the distal capture portion in a distal direction that define an interior cavity to receive the proximal stopper. The proximal and distal capture portions of the apex capture device define a stent capture state.

Abstract: A method for automatic endovascular alignment of a prosthesis includes loading the prosthesis in a distal delivery assembly, positioning a guidewire into a curved implantation site, and threading a guidewire lumen over the guidewire with the delivery assembly and into an implantation site to at least approximately align the curved distal portion to a curve of a curved implantation site and, thereby aligning the prosthesis.

Abstract: A delivery system and kit for endovascularly delivering a prosthesis along a guidewire to an curved implantation site includes a control handle having a handle body with a prosthesis movement control assembly movably disposed thereto. A proximal end of a catheter is connected to the control handle. A prosthesis delivery assembly is movably disposed in the catheter. The delivery assembly has a guidewire lumen slidably receiving therein the guidewire and having a curved distal end orienting the delivery assembly when passing through a curved vessel portion. A method for automatic endovascular alignment of the prosthesis includes loading it in the distal delivery assembly, positioning the guidewire into the curved implantation site, and threading the guidewire lumen over the guidewire with the delivery assembly and into the implantation site to at least approximately align the curved distal portion to a curve of the curved implantation site and, thereby, orient the prosthesis.