Patents by Inventor Gerry Oxford

Gerry Oxford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for generating the inner ear and other cranial placode-derived tissues using pluripotent stem cells
    Patent number: 10308911
    Abstract: Disclosed herein are methods and compositions for generating cultures and isolated cell populations containing preplacodal ectoderms cells, otic placode cells, and inner ear sensory hair cells derived from pluripotent cells by modulating TGF?, BMP, and FGF signaling pathways under defined culture conditions. Also described are methods for obtaining non-otic placodal tissues from pluripotent stem cells. Methods for identifying agents that induce or enhance differentiation and generation of hair cells are also disclosed. Methods for identifying cytoprotective agents for hair cells are also described.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: June 4, 2019
    Assignee: Indiana University Research & Technology Corporation
    Inventors: Eri Hashino, Gerry Oxford, Karl R. Koehler
  • METHODS FOR GENREATING THE INNER EAR AND OTHER CRANIAL PLACODE-DERIVED TISSUES USING PLURIPOTENT STEM CELLS
    Publication number: 20170240858
    Abstract: Disclosed herein are methods and compositions for generating cultures and isolated cell populations containing preplacodal ectoderms cells, otic placode cells, and inner ear sensory hair cells derived from pluripotent cells by modulating TGF?, BMP, and FGF signaling pathways under defined culture conditions. Also described are methods for obtaining non-otic placodal tissues from pluripotent stem cells. Methods for identifying agents that induce or enhance differentiation and generation of hair cells are also disclosed. Methods for identifying cytoprotective agents for hair cells are also described.
    Type: Application
    Filed: March 1, 2017
    Publication date: August 24, 2017
    Inventors: Eri Hashino, Gerry Oxford, Karl R. Koehler
  • Methods for generating the inner ear and other cranial placode-derived tissues using pluripotent stem cells
    Patent number: 9624468
    Abstract: Disclosed herein are methods and compositions for generating cultures and isolated cell populations containing preplacodal ectoderms cells, otic placode cells, and inner ear sensory hair cells derived from pluripotent cells by modulating TGF?, BMP, and FGF signaling pathways under defined culture conditions. Also described are methods for obtaining non-otic placodal tissues from pluripotent stem cells. Methods for identifying agents that induce or enhance differentiation and generation of hair cells are also disclosed. Methods for identifying cytoprotective agents for hair cells are also described.
    Type: Grant
    Filed: May 6, 2013
    Date of Patent: April 18, 2017
    Assignee: Indiana University Research & Technology Corporation
    Inventors: Eri Hashino, Gerry Oxford, Karl R. Koehler
  • METHODS FOR GENERATING THE INNER EAR AND OTHER CRANIAL PLACODE-DERIVED TISSUES USING PLURIPOTENT STEM CELLS
    Publication number: 20150125953
    Abstract: Disclosed herein are methods and compositions for generating cultures and isolated cell populations containing preplacodal ectoderms cells, otic placode cells, and inner ear sensory hair cells derived from pluripotent cells by modulating TGF?, BMP, and FGF signaling pathways under defined culture conditions. Also described are methods for obtaining non-otic placodal tissues from pluripotent stem cells. Methods for identifying agents that induce or enhance differentiation and generation of hair cells are also disclosed. Methods for identifying cytoprotective agents for hair cells are also described.
    Type: Application
    Filed: May 6, 2013
    Publication date: May 7, 2015
    Inventors: Eri Hashino, Gerry Oxford, Karl R. Koehler