Patents by Inventor Gert Ludwig Duveneck
Gert Ludwig Duveneck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8053225Abstract: A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to the (geometrical) arrangement of the sample compartments, combined with the base plate. The arrangement allows for supplying to or removing from the sample compartments, which can be arranged at a high quantity on a small base area, even very small amounts of samples or reagents.Type: GrantFiled: January 28, 2010Date of Patent: November 8, 2011Assignee: Bayer Technology Services GmbHInventors: Eveline Schürmann-Mader, Andreas Peter Abel, Martin Andreas Bopp, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Nania Graciela Schärer-Hernández, Eginhard Schick
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Patent number: 7927868Abstract: A device includes a planar optical waveguide, as part of a sensor platform, and, connected to the platform directly or by means of a sealing medium, a sealing layer. The sealing layer forms either directly or by means of a sealing medium a tightly sealing layer. The sealing layer includes a multitude of recesses at least open towards the sensor platform, which form a corresponding multitude of sample compartments in a 2-dimensional arrangement.Type: GrantFiled: March 17, 2010Date of Patent: April 19, 2011Assignee: Bayer Technology Services GmbHInventors: Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Eveline Schürmann-Mader
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Publication number: 20100227773Abstract: A device includes a planar optical waveguide, as part of a sensor platform, and, connected to the platform directly or by means of a sealing medium, a sealing layer. The sealing layer forms either directly or by means of a sealing medium a tightly sealing layer. The sealing layer includes a multitude of recesses at least open towards the sensor platform, which form a corresponding multitude of sample compartments in a 2-dimensional arrangement.Type: ApplicationFiled: March 17, 2010Publication date: September 9, 2010Inventors: Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Eveline Schürmann-Mader
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Publication number: 20100130370Abstract: A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to the (geometrical) arrangement of the sample compartments, combined with the base plate. The arrangement allows for supplying to or removing from the sample compartments, which can be arranged at a high quantity on a small base area, even very small amounts of samples or reagents.Type: ApplicationFiled: January 28, 2010Publication date: May 27, 2010Inventors: Eveline Schurmann-Mader, Andreas Peter Abel, Martin Andreas Bopp, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Mtthias Kresbach, Michael Pawlak, Nania Graciela Scharer-Hernandez, Eginhard Schick
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Patent number: 7708945Abstract: A device includes a planar optical waveguide, as part of a sensor platform, and, connected to the platform directly or by means of a sealing medium, a sealing layer. The sealing layer forms either directly or by means of a sealing medium a tightly sealing layer. The sealing layer includes a multitude of recesses at least open towards the sensor platform, which form a corresponding multitude of sample compartments in a 2-dimensional arrangement.Type: GrantFiled: August 3, 2000Date of Patent: May 4, 2010Assignee: Bayer Technology Services GmbHInventors: Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Eveline Schürmann-Mader
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Patent number: 7678565Abstract: A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to the (geometrical) arrangement of the sample compartments, combined with the base plate. The arrangement allows for supplying to or removing from the sample compartments, which can be arranged at a high quantity on a small base area, even very small amounts of samples or reagents.Type: GrantFiled: February 21, 2008Date of Patent: March 16, 2010Assignee: Bayer Technology Services GmbHInventors: Eveline Schürmann-Mader, Andreas Peter Abel, Martin Andreas Bopp, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Nania Graciela Schärer-Hernández, Eginhard Schick
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Patent number: 7645612Abstract: The invention is related to different embodiments of a kit for the simultaneous qualitative and/or quantitative determination of a multitude of analytes comprising a sensor platform comprising an optical thin-film waveguide with a layer (a) transparent at least at an excitation wavelength on a layer (b) with lower refractive index than layer (a), also transparent at least at said excitation wavelength, and at least one grating structure (c) modulated in said layer (a), for the incoupling of said excitation light into layer (a), at least one array of biological or biochemical or synthetic recognition elements immobilized in discrete measurement areas (d) directly or by means of an adhesion-promoting layer on layer (a), for specific recognition and/or binding of said analytes and/or for specific interaction with said analytes, means for laterally resolved referencing of the excitation light intensity available in the measurement areas, and optionally means for the calibration of one or more luminescences genType: GrantFiled: April 4, 2008Date of Patent: January 12, 2010Assignee: Bayer Technology Services GmbHInventors: Michael Pawlak, Eginhard Schick, Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Eveline Schürmann-Mader, Martin Andreas Bopp
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Publication number: 20090224173Abstract: The invention relates to a variable embodiment of a grating waveguide structure, based on a planar thin-film waveguide with a first optically transparent layer (a) on a second optically transparent layer (b) having a lower refractive index than layer (a), and a grating structure (c) modulated in layer (a), wherein the intensity of an excitation light irradiated at the resonance angle for incoupling into layer (a) is enhanced by at least a factor of 100 on layer (a) and within layer (a), at least in the region of the grating structure (c), in comparison with the intensity of said excitation light on a substrate surface without incoupling of the excitation light. The invention also relates to an optical system with an excitation light source and an embodiment of a grating waveguide structure according to the invention, and to a method for enhancing an excitation light intensity, and to the use thereof in bioanalytical detection processes, in non-linear optics or in telecommunications or communications industry.Type: ApplicationFiled: December 31, 2008Publication date: September 10, 2009Inventors: Gert Ludwig Duveneck, Martin Andreas Bopp, Michael Pawlak, Markus Ehrat, Gerd Marowsky
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Publication number: 20090054263Abstract: The invention relates to variable embodiments of a grating waveguide structure which enables to determine locally resolved changes of the resonance conditions for the incoupling of an excitation light into the waveguiding layer (a) of a stratified optical waveguide by means of a grating structure (c) modulated in said layer (a) or for outcoupling of a light guided in layer (a). The inventive system comprises arrays of measurement areas produced on the grating waveguide structure having different immobilized biological or biochemical or synthetic recognition elements for simultaneously binding and determining one or more analytes, wherein said excitation light is simultaneously irradiated onto an entire array of measurement areas, and the degree of satisfaction of the resonance condition for the incoupling of light into the layer (a) towards said measurement areas is simultaneously measured.Type: ApplicationFiled: August 5, 2008Publication date: February 26, 2009Inventors: Michael Pawlak, Markus Ehrat, Gert Ludwig Duveneck, Martin Andreas Bopp
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Publication number: 20080299008Abstract: A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to the (geometrical) arrangement of the sample compartments, combined with the base plate. The arrangement allows for supplying to or removing from the sample compartments, which can be arranged at a high quantity on a small base area, even very small amounts of samples or reagents.Type: ApplicationFiled: February 21, 2008Publication date: December 4, 2008Inventors: Eveline Schurmann-Mader, Andreas Peter Abel, Martin Andreas Bopp, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Nania Graciela Scharer-Hernandez, Eginhard Schick
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Publication number: 20080212070Abstract: The invention is related to different embodiments of a kit for the simultaneous qualitative and/or quantitative determination of a multitude of analytes comprising a sensor platform comprising an optical thin-film waveguide with a layer (a) transparent at least at an excitation wavelength on a layer (b) with lower refractive index than layer (a), also transparent at least at said excitation wavelength, and at least one grating structure (c) modulated in said layer (a), for the incoupling of said excitation light into layer (a), at least one array of biological or biochemical or synthetic recognition elements immobilized in discrete measurement areas (d) directly or by means of an adhesion-promoting layer on layer (a), for specific recognition and/or binding of said analytes and/or for specific interaction with said analytes, means for laterally resolved referencing of the excitation light intensity available in the measurement areas, and optionally means for the calibration of one or more luminescences genType: ApplicationFiled: April 4, 2008Publication date: September 4, 2008Inventors: Michael Pawlak, Eginhard Schick, Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Eveline Schurmann-Mader, Martin Andreas Bopp
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Patent number: 7396675Abstract: The invention is related to different embodiments of a kit for the simultaneous qualitative and/or quantitative determination of a multitude of analytes comprising a sensor platform comprising an optical thin-film waveguide with a layer (a) transparent at least at an excitation wavelength on a layer (b) with lower refractive index than layer (a), also transparent at least at said excitation wavelength, and at least one grating structure (c) modulated in said layer (a), for the incoupling of said excitation light into layer (a), at least one array of biological or biochemical or synthetic recognition elements immobilized in discrete measurement areas (d) directly or by means of an adhesion-promoting layer on layer (a), for specific recognition and/or binding of said analytes and/or for specific interaction with said analytes, means for laterally resolved referencing of the excitation light intensity available in the measurement areas, and optionally means for the calibration of one or more luminescences genType: GrantFiled: May 25, 2001Date of Patent: July 8, 2008Assignee: Bayer Technology Services GmbHInventors: Michael Pawlak, Eginhard Schick, Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Eveline Schürmann-Mader, Martin Andreas Bopp
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Patent number: 7358079Abstract: A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to the (geometrical) arrangement of the sample compartments, combined with the base plate. The arrangement allows for supplying to or removing from the sample compartments, which can be arranged at a high quantity on a small base area, even very small amounts of samples or reagents.Type: GrantFiled: December 13, 2000Date of Patent: April 15, 2008Assignee: Bayer Technology Services GmbHInventors: Eveline Schürmann-Mader, Andreas Peter Abel, Martin Andreas Bopp, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Michael Pawlak, Nania Graciela Schärer-Hernández, Eginhard Schick
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Publication number: 20040253596Abstract: The invention relates to a recognition surface on a carrier with an (in relation to the surface) optimal binding capacity for recognizing and binding one or more analytes from one or more samples brought into contact with this surface, whereinType: ApplicationFiled: February 27, 2004Publication date: December 16, 2004Inventors: Michael Pawlak, Gert Ludwig Duveneck, Ning-Ping Huang, Susan Margaret De Paul, Marcus Textor, Rolf Hofer, Eveline Schurmann-Mader
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Publication number: 20040058385Abstract: The invention relates to various embodiments of a kit for simultaneous qualitative and/or quantitative determination of numerous analytes, which in particular enables the density of immobilized biological or biochemical or synthetic recognition elements for the determination of said analytes, i.e. the coating density of the measurement area dedicated for these recognition elements, to be referenced. The invention also relates to analytical systems based on the kit according the invention as well as to methods carried out therewith to determine one or more analytes and the use thereof.Type: ApplicationFiled: May 15, 2003Publication date: March 25, 2004Inventors: Andreas Peter Abel, Gerhard Matthias Kresbach, Gert Ludwig Duveneck, Nania Graciela Scharer-Hernandez
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Publication number: 20040052489Abstract: The invention relates to a variable embodiment of an optical structure, comprising an optical waveguide with a waveguiding layer (a), being optically transparent at least at an excitation wavelength, wherein the intensity of an excitation light in-coupled into layer (a) and guided in layer (a) is high enough within layer (a) and on layer (a), that molecules located on the surface of layer (a) or within a distance of less than 200 nm, which are capable of luminescence and/or photo-reactive, can be excited by multi-photon excitation, preferably by two-photon excitation. Thereby, embodiments are preferred which allow for a multi-photon excitation along macroscopic distances or on extended surfaces, along the trace of the excitation light guided in layer (a).Type: ApplicationFiled: September 29, 2003Publication date: March 18, 2004Inventors: Gert Ludwig Duveneck, Martin Andreas Bopp, Michael Pawlak, Markus Ehrat, Gerd Marowsky
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Publication number: 20040046128Abstract: A sensor platform, based on a planar optical thin-film waveguide is used to determine one or more luminescences from one or more measurement areas on the sensor platform. The sensor platform has a first optically transparent layer on a second optically transparent layer of lower refractive index than the first optically transparent layer, and at least one grating structure to incouple excitation light to the measurement areas or to outcouple luminescence light from the measurement areas. An optical system is also used for luminescence determination. Further, an analytical system having the sensor platform, the optical system, and a supply device to bring one or more samples in contact with the measurement areas on the sensor platform is used for luminescence determination.Type: ApplicationFiled: August 28, 2003Publication date: March 11, 2004Inventors: Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach
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Publication number: 20030148542Abstract: The invention is related to different embodiments of a kit for the simultaneous qualitative and/or quantitative determination of a multitude of analytes comprisingType: ApplicationFiled: November 27, 2002Publication date: August 7, 2003Inventors: Michael Pawlak, Eginhard Schick, Andreas Peter Abel, Gert Ludwig Duveneck, Markus Ehrat, Gerhard Matthias Kresbach, Eveline Schurmann-Mader, Martin Andreas Bopp
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Publication number: 20030138208Abstract: The invention relates to variable embodiments of a grating waveguide structure which enables to determine locally resolved changes of the resonance conditions for the incoupling of an excitation light into the waveguiding layer (a) of a stratified optical waveguide by means of a grating structure (c) modulated in said layer (a) or for outcoupling of a light guided in layer (a). The inventive system comprises arrays of measurement areas produced on the grating waveguide structure having different immobilized biological or biochemical or synthetic recognition elements elements for simultaneously binding and determining one or more analytes, wherein said excitation light is simultaneously irradiated onto an entire array of measurement areas, and the degree of satisfaction of the resonance condition for the incoupling of light into the layer (a) towards said measurement areas is simultaneously measured.Type: ApplicationFiled: November 5, 2002Publication date: July 24, 2003Inventors: Michael Pawlak, Markus Ehrat, Gert Ludwig Duveneck, Martin Andreas Bopp
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Publication number: 20030108291Abstract: The invention relates to a variable embodiment of a grating waveguide structure, based on a planar thin-film waveguide with a first optically transparent layer (a) on a second optically transparent layer (b) having a lower refractive index than layer (a), and a grating structure (c) modulated in layer (a), wherein the intensity of an excitation light irradiated at the resonance angle for incoupling into layer (a) is enhanced by at least a factor of 100 on layer (a) and within layer (a), at least in the region of the grating structure (c), in comparison with the intensity of said excitation light on a substrate surface without incoupling of the excitation light. The invention also relates to an optical system with an excitation light source and an embodiment of a grating waveguide structure according to the invention, and to a method for enhancing an excitation light intensity, and to the use thereof in bioanalytical detection processes, in non-linear optics or in telecommunications or communications industry.Type: ApplicationFiled: October 8, 2002Publication date: June 12, 2003Inventors: Gert Ludwig Duveneck, Martin Andreas Bopp, Michael Pawlak, Markus Ehrat