Patents by Inventor Gertrude C. Kasitu

Gertrude C. Kasitu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for mass production of GMP paclitaxel and related taxanes
    Publication number: 20030032820
    Abstract: A process for the purification of paclitaxel and/or cephalomannine and/or 10-DAB III and/or 9-DHAB III is described. A series of extractions, separations, and purifications provides these products in commercial quantities with high purity. The source for these natural products is from readily available renewable biomaterials, such as leaves and stems from the yew, T. canadensis.
    Type: Application
    Filed: September 25, 2002
    Publication date: February 13, 2003
    Inventors: Gertrude C. Kasitu, Japheth Noah, Qasim Khan
  • Process for mass production of GMP paclitaxel and related taxanes
    Patent number: 6469186
    Abstract: A process for the purification of paclitaxel and/or cephalomannine and/or 10-DAB III and/or 9-DHAB III is described. A series of extractions, separations, and purifications provides these products in commercial quantities with high purity. The source for these natural products is from readily available renewable biomaterials, such as leaves and stems from the yew, T. canadensis.
    Type: Grant
    Filed: November 7, 2001
    Date of Patent: October 22, 2002
    Assignee: Actipharm, Inc.
    Inventors: Gertrude C. Kasitu, Japheth Noah, Qasim Khan
  • Process for mass production of GMP paclitaxel and related taxanes
    Publication number: 20020151579
    Abstract: A process for the purification of paclitaxel and/or cephalomannine and/or 10-DAB III and/or 9-DHAB III is described. A series of extractions, separations, and purifications provides these products in commercial quantities with high purity. The source for these natural products is from readily available renewable biomaterials, such as leaves and stems from the yew, T. canadensis.
    Type: Application
    Filed: November 7, 2001
    Publication date: October 17, 2002
    Inventors: Gertrude C. Kasitu, Japheth Noah, Qasim Khan
  • Conversion of 9-dihydro-13-acetylbaccatin III to baccatin III and 10-deacetyl baccatin III
    Publication number: 20010041803
    Abstract: Novel methods and synthetic intermediates to prepare baccatin III and 10-deacetylbaccatin from readily available 9-dihydro-13-acetylbaccatin III are described. Selective protection and deprotection of the C-7 hydroxyl functionality provides an entry into facile synthesis of novel taxol intermediates, as well as, providing new methods for the preparation of paclitaxel and docetaxel in large scale. Selective oxidation of the C-9 hydroxyl without the need for protection of the C-7 hydroxyl is described.
    Type: Application
    Filed: March 19, 2001
    Publication date: November 15, 2001
    Inventors: Gertrude C. Kasitu, Japheth W. Noah