Patents by Inventor Gessica Filocamo

Gessica Filocamo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal antibody anti-FGFR4
    Patent number: 11643467
    Abstract: The present disclosure relates to monoclonal antibodies anti-FGFR4 and their use as medicaments and diagnostic agents. In particular, it relates to an antibody which specifically binds to the acid box domain of FGFR4 and to specific portions thereof. Nucleic acids coding for said antibody, vectors and host cells for their expression and production, antibody-drug conjugates and pharmaceutical compositions comprising said antibody are also within the scope of the present disclosure. The present disclosure also relates to antibodies anti-FGFR4 for use for detecting, killing, affecting or inhibiting development and/or differentiation of colon cancer stem cells.
    Type: Grant
    Filed: August 1, 2018
    Date of Patent: May 9, 2023
    Assignee: EXIRIS S.R.L.
    Inventors: Paola Gallinari, Chantal Paolini, Gessica Filocamo, Mirko Brunetti, Armin Lahm, Hans-Friedrich Grunert, John Thompson, Lucia Ricci-Vitiani, Mauro Biffoni
  • MONOCLONAL ANTIBODY ANTI-FGFR4
    Publication number: 20210230280
    Abstract: The present disclosure relates to monoclonal antibodies anti-FGFR4 and their use as medicaments and diagnostic agents. In particular, it relates to an antibody which specifically binds to the acid box domain of FGFR4 and to specific portions thereof. Nucleic acids coding for said antibody, vectors and host cells for their expression and production, antibody-drug conjugates and pharmaceutical compositions comprising said antibody are also within the scope of the present disclosure. The present disclosure also relates to antibodies anti-FGFR4 for use for detecting, killing, affecting or inhibiting development and/or differentiation of colon cancer stem cells.
    Type: Application
    Filed: August 1, 2018
    Publication date: July 29, 2021
    Inventors: Paola GALLINARI, Chantal PAOLINI, Gessica FILOCAMO, Mirko BRUNETTI, Armin LAHM, Hans-Friedrich GRUNERT, John THOMPSON, Lucia RICCI-VITIANI, Mauro BIFFONI
  • HC-CDR3-only libraries with reduced combinatorial redundancy and optimized loop length distribution
    Patent number: 10745696
    Abstract: The present invention provides for a library of vectors comprising human HC-CDR3 regions of varying length, wherein the diversity of said library is focused on the HC-CDR3 region only and diversity has been optimized such that redundancy is reduced for short HC-CDR3 loops and coverage of HC-CDR3 region variants for longer loop lengths has been increased. The library of the present invention is displayed on phage for selection against target antigens.
    Type: Grant
    Filed: February 14, 2019
    Date of Patent: August 18, 2020
    Assignee: ITALFARMACO S.P.A.
    Inventors: Armin Lahm, Christian Steinkuehler, Gessica Filocamo
  • Modulators of HCV replication
    Patent number: 8012982
    Abstract: The present invention is directed to compounds of formula (I): where X, Y, R1, R2 and R3 are defined therein, which can act as modulators of viral replication and/or virus production, especially of the hepatitis C virus (HCV).
    Type: Grant
    Filed: September 29, 2005
    Date of Patent: September 6, 2011
    Assignee: Istituto di Ricerche Biologia Molecolare P. Angeletti SpA
    Inventors: Immacolata Conte, Caterina Ercolani, Claudio Giuliano, Giovanni Migliaccio, Gessica Filocamo, legal representative, Veronica Suriano, legal representative, Ian Stansfield
  • Inhibitors of mammalian hdac 11 useful for treating hdac 11 mediated disorders
    Publication number: 20090253769
    Abstract: The present invention, relies, in part, on the discovery of the role of HDAC 11 in various cell proliferative disorders including cancer. In the main, the invention provides for methods of inhibiting HDAC 11 as a means of treating cell proliferative disorders. Reagents for use in inhibiting human HDAC 11 are also provided.
    Type: Application
    Filed: January 18, 2005
    Publication date: October 8, 2009
    Inventors: Gessica Filocamo, Christian Steinkuhler
  • Modulators of hcv replication
    Publication number: 20090069344
    Abstract: The present invention is directed to compounds of formula (I): where X, Y, R1, R2 and R3 are defined therein, which can act as modulators of viral replication and/or virus production, especially of the hepatitis C virus (HCV).
    Type: Application
    Filed: September 29, 2005
    Publication date: March 12, 2009
    Inventors: Immacolata Conte, Caterina Ercolani, Claudio Giuliano, Giovanni Migliaccio, Ian Stansfield, Gessica Filocamo, Veronica Suriano