Patents by Inventor Geza Toth

Geza Toth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isotopically marked quinoline derivatives as adenosin A3 receptor ligands
    Patent number: 7964731
    Abstract: The invention relates to adenozin A3 receptor ligands labeled with iodine isotops of mass number 125, within those favorably to antagonists and their isomers, to the experimental materials containing them, to a process for the preparation of the compounds of the general formula (I) and their isomers, to the new intermediates of the general formula (II) and to the preparation thereof.
    Type: Grant
    Filed: May 14, 2007
    Date of Patent: June 21, 2011
    Assignee: Sanofi-Aventis
    Inventors: Geza Timari, Kinga Boer, Geza Toth, Csaba Tomboly
  • ISOTOPICALLY MARKED QUINOLINE DERIVATIVES AS ADENOSIN A3 RECEPTOR LIGANDS
    Publication number: 20080027225
    Abstract: The invention relates to adenozin A3 receptor ligands labeled with iodine isotops of mass number 125, within those favourably to antagonists and their isomers, to the experimental materials containing them, to a process for the preparation of the compounds of the general formula (I) and their isomers, to the new intermediates of the general formula (II) and to the preparation thereof.
    Type: Application
    Filed: May 14, 2007
    Publication date: January 31, 2008
    Applicant: Sanofi-Aventis
    Inventors: Geza Timari, Kinga Boer, Geza Toth, Csaba Tomboly
  • Novel GnRH analogues with antitumour effects and pharmaceutical compositions thereof
    Publication number: 20060189539
    Abstract: The present invention provides peptides and pharmacologically active compounds including gonadotropin-releasing hormone (GnRH) analogues according to formulas of the invention, wherein the compounds show an antitumour effect. The invention additionally provides compositions including these peptides and compounds.
    Type: Application
    Filed: October 28, 2003
    Publication date: August 24, 2006
    Inventors: Sandor Lovas, Richard Murphy, Geza Toth, Adrienn Kalnay, Dezso Gaal, Istvan Palyi, Gizella Turi, Borbala Vincze, Imre Mezom, Henrietta Tanai, Zsolt Vadasz, Istvan Teplan, Janos Seprodi, Edit Szabo, Janos Pato, Melinda Mora
  • GnRH analogues with antitumour effects and pharmaceutical compositions thereof
    Patent number: 6664369
    Abstract: The present invention provides peptides and pharmacologically active compounds including gonadotropin-releasing hormone (GnRH) analogues according to formulas of the invention, wherein the compounds show an antitumor effect. The invention additionally provides compositions including these peptides and compounds.
    Type: Grant
    Filed: July 27, 2000
    Date of Patent: December 16, 2003
    Assignee: Creighton University
    Inventors: Sandor Lovas, Richard F. Murphy, Geza Toth, Adrienn Kalnay, Istvan Palyi, Gizella Turi, Borbala Vincze, Imre Mezom, Zsolt Vadasz, Istvan Teplan, Janos Seprodi, Melinda Mora
  • Anti-tumor effects of GnRH-III
    Patent number: 5593965
    Abstract: The present invention provides a novel pharmaceutical composition for the treatment of breast cancer. Also provided are various methods of treating breast cancer.
    Type: Grant
    Filed: October 20, 1994
    Date of Patent: January 14, 1997
    Assignee: Creighton University
    Inventors: Sandor Lovas, J. Michael Conlon, Borbala Vincze, Istvan Palyi, Dezso Gaal, Adrienn Kalnay, Imre Mezo, Istvan Teplan, Geza Toth, Magdolna Kovacs
  • Process for the preparation of polyhalogenphenyl carbamates
    Patent number: 4347377
    Abstract: The invention concerns a new process for the preparation of polyhalogenphenyl carbamates of the formula (I)R.sup.2 -OCONHR.sup.1 (I)whereinR.sup.1 is alkyl, aralkyl or aryl, where the aromatic rings may optionally be substituted; andR.sup.2 is phenyl substituted with three, four or five halogens, through intermediates of the formula (IV)(R.sup.2 --O).sub.2 C.dbd.NR.sup.1 (IV)wherein R.sup.1 and R.sup.2 are as defined above.The compounds of the formula (I) are valuable acylating agents. The intermediates of the formula (IV) are new compounds, which are also encompassed by the invention.
    Type: Grant
    Filed: September 19, 1980
    Date of Patent: August 31, 1982
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
    Inventors: Istvan Bitter, Rudolf Soos, Geza Toth, Laszlo Toke, Gabor Szabo
  • Process for the preparation of substituted-phenyl-N-alkyl-carbamates
    Patent number: 4150034
    Abstract: A process for the preparation of a substituted-phenyl-N-alkyl-carbamate of the formula ##STR1## wherein R.sup.1 and R.sup.2 form part of a carbamoyloxy group and are identical or different and each is hydrogen or lower alkyl,R is halogen, formyl group or a group of the formula ##STR2## in ortho or meta-position to the carbamoyloxy group, wherein X.sup.1 and X.sup.2 are identical or different and each is oxygen or sulphur andR.sup.3 and R.sup.4 are identical or different and each is alkyl, alkenyl or alkynyl or together form a 5-membered saturated or unsaturated heterocycle in which X.sup.1 and X.sup.2 are heteroatoms, said process comprising reacting a compound of the formula ##STR3## in the presence of a base with a compound of the formula ##STR4## wherein A is phenyl substituted with two or more electron withdragroups.
    Type: Grant
    Filed: August 10, 1977
    Date of Patent: April 17, 1979
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
    Inventors: Tamas U. Kallay, Gabor Szabo, Geza Toth, Kalman Harsanyi
  • 2-(5-Nitro-furfurylidene)-amino-benzimidoles and fungicidal compositions containing the same
    Patent number: 4136189
    Abstract: A fungicidal composition contains as an active ingredient a compound of the formula ##STR1## wherein R.sub.1 is hydrogen or a carbamoyl group, R.sub.2, R.sub.3 and R.sub.5 are hydrogen or C.sub.1 - C.sub.7 alkyl.
    Type: Grant
    Filed: September 10, 1976
    Date of Patent: January 23, 1979
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
    Inventors: Geza Toth, Istvan Toth
  • Process for the preparation of carbamate derivatives
    Patent number: 4086246
    Abstract: A process for the preparation of a compound of the formula: ##STR1## wherein R.sup.1 is alkyl, alkyl substituted by halogen, alkyl substituted by alkoxy, aryl, aryl substituted by halogen, aryl substituted by alkyl, aryl substituted by alkoxy, aralkyl, aralkyl substituted by alkoxy, cycloalkyl, cycloalkyl substituted by halogen, cycloalkyl substituted by alkyl or cycloalkyl substituted by alkoxy, andR.sup.2 is an aromatic group, an aromatic group substituted by alkyl, an aromatic group substituted by halogen, an aromatic group substituted by alkoxy, a heteroaromatic group, a heteroaromatic group substituted by alkyl, a heteroaromatic group substituted by halogen, or a heteroaromatic group substituted by alkoxy, by the reaction of phosgene with a phenol of the formula:R.sup.2 -OHand further by the reaction of a primary amine of the formula:R'--NH.sub.
    Type: Grant
    Filed: April 30, 1976
    Date of Patent: April 25, 1978
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara
    Inventors: Geza Toth, Istvan Toth, Tibor Montay
  • Benzimidazole derivatives and fungicidal composition and method
    Patent number: 4024269
    Abstract: A fungicidal and fungistatic composition contains, as an effective ingredient, a compound of the formula ##STR1## and antifungal and pharmaceutically effective salts thereof wherein R.sup.1 is H and R.sup.5 is a group with the formula ##STR2## in which R.sup.2 and R.sup.3 are each hydrogen or C.sub.1 -C.sub.6 alkyl.
    Type: Grant
    Filed: June 16, 1976
    Date of Patent: May 17, 1977
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
    Inventors: Geza Toth, Istvan Toth
  • Substituted carbamoyl benzimidazole derivatives with antifungal properties
    Patent number: 3978075
    Abstract: Antifungal substituted carbamoyl benzimidazole compounds of the formula ##SPC1##Wherein R.sup.2 and R.sup.3 are hydrogen or alkyl and R.sup.4 is aryl, alkyl or cycloalkyl. The compounds can be used as seed treatment.
    Type: Grant
    Filed: April 25, 1975
    Date of Patent: August 31, 1976
    Assignee: Chinoin Gyogyszer-es Vegyeszeti Termekek Gyara RT
    Inventors: Geza Toth, Istvan Toth
  • Method of controlling plant growth
    Patent number: 3964894
    Abstract: A method of controlling plant growth wherein the plant or its seed are treated with thiazolyl-indolyl compounds.
    Type: Grant
    Filed: April 8, 1974
    Date of Patent: June 22, 1976
    Assignee: Chinoin Gyogyszer-es Vegyeszeti Termekek Gyara RT
    Inventors: Geza Toth, Gabor Szabo, Gyorgy Eibel, Eva Somfai