Abstract: Silicone dosage forms adapted for the continuous and controlled release of iodine values, notably to domestic water supplies for the treatment of the various disease states attributed to iodine deficiency, are shaped from (A) a diorganopolysiloxane matrix resin; (B) a reinforcing amount of a filler material (B.sub.1) therefor and/or an organic peroxide (B.sub.2); and (C) a therapeutically effective amount of at least one water soluble, nontoxic, organic and/or inorganic iodine compound which is in solid or liquid state at ambient temperature.

Abstract: Silicone dosage forms adapted for the continuous and controlled release of iodine values, notably to domestic water supplies for the treatment of the various disease states attributed to iodine deficiency, are heat-shaped from (A) a thermoplastic silicone copolymer, and (B) a therapeutically effective amount of at least one water soluble, nontoxic, organic and/or inorganic iodine compound which is in solid state at ambient temperature.

Abstract: Polyester/silicon co-crosslinked polymer substrates at least partially degradable by hydrolysis, well adopted as matrices for the controlled release of a wide variety of active agents therefrom, are prepared by controlledly co-crosslinking (a) at least one diorganopolysiloxane having at least two hydroxyl groups per molecule and (b) an oligomeric polylactic and/or polyglycolic polyester .alpha.,.omega.-diol, with an effective co-crosslinking amount of (c) an organic polyisocyanate.

Abstract: Polycondensation silicone elastomer dosage forms adapted for the continuous and controlled release of iodine values, notably to domestic water supplies for the treatment of the various disease states attributed to iodine deficiency, are shaped from (A) at least one diorganopolysiloxane oil bearing at least two condensable or hydrolyzable groups, or a single hydroxyl group, at each end of the polymer chain; (B) a therapeutically effective amount of at least one water soluble, nontoxic, organic and/or inorganic iodine compound which is in solid or liquid state at ambient temperature and which does not inhibit curing of the composition into an elastomer; (C) a catalytically effective amount of a polycondensation catalyst; and optionally, (D) a silane containing at least three condensable or hydrolyzable groups.

Abstract: Magnetizable composite particles, optionally in aqueous dispersion, consisting of a matrix based on a crosslinked organopolysiloxane, optionally bearing nonvinyl reactive and/or ionic units and magnetizable components less than 300 angstroms in diameter encapsulated in the matrix. The magnetizable composite particles are prepared by homogenizing a solution of the organopolysiloxane, an organohydrogenopolysiloxane optionally bearing ionic and/or reactive units, and a magnetic fluid, in the presence of water and a surfactant, performing a hydrosilylation in an aqueous emulsion, removing the organic solvents and the organic carrier liquid, and at least partially removing the water. The magnetizable composite particles are useful in biological applications.

Abstract: Magnetizable microspheres, optionally in aqueous dispersion, consisting of a matrix of at least one organopolysiloxane optionally bearing Si-vinyl groups or reactive and/or ionic units and magnetizable particles less than 300 angstroms in diameter encapsulated in the matrix. The magnetizable microspheres are prepared by homogenizing a solution of the organopolysiloxane and a magnetic fluid in the presence of water and a surfactant, removing the solvent for the organopolysiloxane and the carrier liquid of the magnetic fluid, and at least partially removing the water. The magnetizable microspheres are useful in biological applications as active supports.

Abstract: Magnetizable composite particles, optionally in aqueous dispersion, consisting of a matrix based on a crosslinked organopolysiloxane, optionally bearing nonvinyl reactive and/or ionic units and magnetizable components less than 300 angstroms in diameter encapsulated in the matrix. The magnetizable composite particles are prepared by homogenizing a solution of the organopolysiloxane, an organohydrogenpolysilioxane optionally bearing ionic and/or reactive units, and a magnetic fluid, in the presence of water and a surfactant, performing a hydrosilylation in an aqueous emulsion, removing the organic solvents and the organic carrier liquid, and at least partially removing the water. The magnetizable composite particles are useful in biological applications.

Abstract: Heat-vulcanized silicone dosage forms adapted for the continuous and controlled release of iodine values, notably to domestic water supplies for the treatment of the various disease states attributed to iodine deficiency, are shaped from (A) a diorganopolysiloxane matrix resin containing at least two vinyl groups bonded to silicon per molecule and having a viscosity of at least 500,000 mPa.s at 25.degree. C.; (B) at least one organohydropolysiloxane containing at least three hydrogen atoms bonded to silicon per molecule; (C) a reinforcing amount of a filler material therefor; (D) a catalytically effective amount of a platinum group metal catalyst; and (E) a therapeutically effective amount of at least one water soluble, nontoxic, organic and/or inorganic iodine compound which is in solid or liquid state at ambient temperature.

Abstract: Polyaddition silicone elastomer dosage forms adapted for the continuous and controlled release of iodine values, notably to domestic water supplies for the treatment of the various disease states attributed to iodine deficiency, are shaped from (A) at least one organopolysiloxane containing at least two vinyl groups bonded to silicon per molecule; (B) at least one organopolysiloxane containing at least three hydrogen atoms bonded to silicon; (C) a catalytically effective amount of a platinum group metal compound; and (D) a therapeutically effective amount of at least one water soluble, nontoxic, organic and/or inorganic iodine compound which is in solid or liquid state at ambient temperature and which does not inhibit the catalytic activity of the platinum group metal compound (C).