Patents by Inventor Gholam H. Hakimelahi

Gholam H. Hakimelahi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phloroglucidic acid and derivatives as antibacterial agents
    Patent number: 6288265
    Abstract: A series of phloroglucide derivatives are synthesized, which possess potent antibacterial activities. They include unsymmetrical phloroglucide analogs, phloroglucides attached to cephalosporins at the C-3′ position, and 7-(phloroglucidamido)cephalosporins.
    Type: Grant
    Filed: September 20, 1999
    Date of Patent: September 11, 2001
    Assignee: National Science Council
    Inventors: Jih Ru Hwu, Shwu-Chen Tsay, Gholam H. Hakimelahi, Chun Chieh Lin, Wen Nan Tseng, Ali A. Moshfegh, Abdolmajid Azaripour, Hasan Mottaghian
  • Phloroglucide derivatives and their pharmceutical use
    Patent number: 6121255
    Abstract: A phloroglucide derivative having the following formula: ##STR1## wherein Q is halogen; X is CH.sub.2 or C.dbd.O; Y is cephalosporin having a formula of ##STR2## wherein Ph is phenyl, Ac is acetoxy, or pharmaceutically acceptable salts thereof, and an antibacterial pharmaceutical composition derived thereof.
    Type: Grant
    Filed: May 4, 1998
    Date of Patent: September 19, 2000
    Assignee: National Science Council
    Inventors: Jih Ru Hwu, Shwu-Chen Tsay, Gholam H. Hakimelahi, Chun Chieh Lin, Wen Nan Tseng, Ali A. Moshfegh, Abdolmajid Azaripour, Hasan Mottaghian
  • Thymidylate analogs and the use thereof
    Patent number: 5760013
    Abstract: Novel thymidylate analogs having the following formula are synthesized in the present invention, which are found active against human immunodeficiency virus type 1 (HIV-1): ##STR1## wherein R.sup.1 is hydrogen, cyano (--CN), halogen or azido (--N.sub.3); R.sup.2 is hydroxyl or an amino ester radical having a formula of --NHR.sup.4 COOR.sup.5, wherein R.sup.4 is a bivalent C.sub.1 -C.sub.4 saturated hydrocarbon and R.sup.5 is C.sub.1 -C.sub.4 alkyl; Me is methyl; and R.sup.
    Type: Grant
    Filed: August 21, 1996
    Date of Patent: June 2, 1998
    Assignee: National Science Council
    Inventors: Jih Ru Hwu, Gholam H. Hakimelahi, Shwu-Chen Tsay
  • Adenylate analogs as potent anti-herpes virus agents
    Patent number: 5733890
    Abstract: Novel adenylate analogs having the following formula are synthesized in the present invention, which are found active against herpes simplex viruses: ##STR1## wherein R.sup.1 is hydroxyl, C.sub.1 -C.sub.4 alkoxy, an amino ester radical of --NHR.sup.3 COOR.sup.4, wherein R.sup.3 is a bivalent C.sub.1 -C.sub.4 saturated hydrocarbon and R.sup.4 is C.sub.1 -C.sub.4 alkyl; and R.sup.2 is hydroxyl, --O.sup.+ NH.sub.
    Type: Grant
    Filed: October 9, 1996
    Date of Patent: March 31, 1998
    Assignee: National Science Council
    Inventors: Jih Ru Hwu, Gholam H. Hakimelahi, Shwu-Chen Tsay, Ali A. Moosavi-Movahedi, Majid M. Sadeghi
  • Esters of retinoic acid and azetidinone derivatives
    Patent number: 4385175
    Abstract: There are disclosed esters of retinoic acid and alcohols which are azetidinone derivatives. These esters are useful as anti-cancer agents.
    Type: Grant
    Filed: March 22, 1982
    Date of Patent: May 24, 1983
    Assignee: Bristol-Myers Company
    Inventors: George Just, Gholam H. Hakimelahi