Patents by Inventor Ghulam Nabi Qazi
Ghulam Nabi Qazi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9192589Abstract: Compounds are described that are effective in enhancing the efficacy of antimicrobial agents. Also described are methods of using such compounds and compositions that include such compounds. The composition includes a chalcone compound and, optionally, an antimicrobial agent.Type: GrantFiled: December 18, 2009Date of Patent: November 24, 2015Assignees: Colgate-Palmolive Company, Council of Scientific and Industrial ResearchInventors: Ravi Subramanyam, Laurence Du-Thumm, Ghulam Nabi Qazi, Inshad Ali Khan, Krishan Avtar Suri, Naresh Kumar Satti, Furqan Ali, Nitin Pal Kalia
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Patent number: 9073860Abstract: The present invention relates to an aromatic substituted pentadienoic acid amides and there use in combination of specific amounts of aromatic amides i.e. 4-alkyl-5-(substituted phenyl)-2 (E),4(E)-pentadienoic acid amides, its geometrical isomers or their dihydro or tetrahydro derivatives and an anti-infective drug useful in potentiating the bioefficacy of antiinfective drug. The combination of the present invention is useful in the treatment of certain infections and disease at lower concentration of anti-infectives necessary to inhibit the growth of microbial strains and may also find applications in reducing the resistance in microorganisms.Type: GrantFiled: October 11, 2013Date of Patent: July 7, 2015Assignee: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCHInventors: Surrinder Koul, Jawahir Lal Koul, Subhash Chandra Taneja, Pankaj Gupta, Inshad Ali Khan, Zahid Mehmood Mirza, Ashwani Kumar, Rakesh Kamal Johri, Monika Pandita, Anita Khosa, Ashok Kumar Tikoo, Subhash Chander Sharma, Vijeshwar Verma, Ghulam Nabi Qazi
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Publication number: 20140073595Abstract: The present invention relates to an aromatic substituted pentadienoic acid amides and there use in combination of specific amounts of aromatic amides i.e. 4-alkyl-5-(substituted phenyl)-2(E),4(E)-pentadienoic acid amides, its geometrical isomers or their dihydro or tetrahydro derivatives and an anti-infective drug useful in potentiating the bioefficacy of antiinfective drug. The combination of the present invention is useful in the treatment of certain infections and disease at lower concentration of anti-infectives necessary to inhibit the growth of microbial strains and may also find applications in reducing the resistance in microorganisms.Type: ApplicationFiled: October 11, 2013Publication date: March 13, 2014Applicant: Council Of Scientific and Industrial ResearchInventors: Surrinder KOUL, Jawahir Lal KOUL, Subhash Chandra TANEJA, Pankaj GUPTA, Inshad Ali KHAN, Zahid Mehmood MIRZA, Ashwani KUMAR, Rakesh Kamal JOHRI, Monika PANDITA, Anita KHOSA, Ashok Kumar TIKOO, Subhash Chander Sharma, Vijeshwar VERMA, Ghulam Nabi QAZI
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Patent number: 8580752Abstract: The present invention relates to an aromatic substituted pentadienoic acid amides and there use in combination of specific amounts of aromatic amides i.e. 4-alkyl-5-(substituted phenyl)-2(E),4(E)-pentadienoic acid amides, its geometrical isomers or their dihydro or tetrahydro derivatives and an anti-infective drug useful in potentiating the bioefficacy of antiinfective drug. The combination of the present invention is useful in the treatment of certain infections and disease at lower concentration of anti-infectives necessary to inhibit the growth of microbial strains and may also find applications in reducing the resistance in microorganisms.Type: GrantFiled: March 29, 2006Date of Patent: November 12, 2013Assignee: Council of Scientitic and Industrial ResearchInventors: Surrinder Koul, Jawahir Lal Koul, Subhash Chandra Taneja, Pankaj Gupta, Inshad Ali Khan, Zahid Mehmood Mirza, Ashwani Kumar, Rakesh Kamal Johri, Monika Pandita, Anita Khosa, Ashok Kumar Tikoo, Subhash Chander Sharma, Vijeshwar Verma, Ghulam Nabi Qazi
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Patent number: 8445700Abstract: The present invention relates to a facile, highly efficient and economical process for the preparation of optically active N-benzyl-3-hydroxypyrrolidine in high yield from a naturally occurring alkaloid vasicine. The natural alkaloid vasicine is used as a precursor of (S)—N-benzyl-3-hydroxypyrrolidine and (R)—N-benzyl-3-hydroxypyrrolidines which can easily be sourced from the medicinal plant Adatoda vasica by the method known in the art and transformed to optical isomers (R) and (S)—N-benzyl-3-hydroxypyrrolidine by the method described in the present invention.Type: GrantFiled: November 24, 2009Date of Patent: May 21, 2013Assignee: Council of Scientific & Industrial ResearchInventors: Subhash Chandra Taneja, Mushtaq Ahmad Aga, Brijesh Kumar, Vijay Kumar Sethi, Samar Singh Andotra, Ghulam Nabi Qazi
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Publication number: 20120251464Abstract: Compounds are described that are effective in enhancing the efficacy of antimicrobial agents. Also described are methods of using such compounds and compositions that include such compounds. The composition includes a chalcone compound and, optionally, an antimicrobial agent.Type: ApplicationFiled: December 18, 2009Publication date: October 4, 2012Applicants: Indian Institute of Integrative Medicine, Colgate-Palmolive ComplanyInventors: Ravi Subramanyam, Laurence Du-Thumm, Ghulam Nabi Qazi, Inshad Ali Khan, Krishan Avtar Suri, Naresh Kumar Satti, Furqan Ali, Nitin Pal Kalia
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Publication number: 20120101285Abstract: The present invention relates to a facile, highly efficient and economical process for the preparation of optically active N-benzyl-3-hydroxypyrrolidine in high yield from a naturally occurring alkaloid vasicine. The natural alkaloid vasicine is used as a precursor of (S)—N-benzyl-3-hydroxypyrrolidine and (R)—N-benzyl-3-hydroxypyrrolidines which can easily be sourced from the medicinal plant Adatoda vasica by the method known in the art and transformed to optical isomers (R) and (S)—N-benzyl-3-hydroxypyrrolidine by the method described in the present invention.Type: ApplicationFiled: November 24, 2009Publication date: April 26, 2012Inventors: Subhash Chandra Taneja, Mushtaq Ahmad Aga, Brijesh Kumar, Vijay Kumar Sethi, Samar Singh Andotra, Ghulam Nabi Qazi
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Publication number: 20120021077Abstract: The present invention deals with a synergistic herbal composition useful for treatment of rheumatic and musculo-skeletal disorders (RMSDs) comprising a base formulation (50-60%) and plant parts and/or extracts of the plant (40-50%) selected from the group consisting of Withania somnifera, Tribulus terrestris, Phyllanthus emblica and Boswellia serrata optionally along with pharmaceutically acceptable excipients. The herbal formulation is capable of causing simultaneous long term decrease in glycosaminoglycan (GAG) release and aggrecan by cartilage explants resulting in reduction of pain, inflammation, stiffness and low degeneration of bones, joints, muscles and other connective tissues. The present invention further deals with a process for the preparation of the said herbal formulation and a method of treating RMSDs using the formulation up to a high safety level and stable for a long durations.Type: ApplicationFiled: July 18, 2008Publication date: January 26, 2012Inventors: Bhushan Patwardhan, Arvind Chopra, Gumdal Narsimulu, Rohini Handa, Lata S. Bichile, Ghulam Nabi Qazi, Arvind Manohar Mujumdar, Venil N. Sumantran, Palpu Pushpangadam, Shanta Mehrotra, Ajay Kumar Singh Rawat, Sayyada Khatoon, Subha Rastogi, Govindarajan Raghavan, Ashwinikumar Raut
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Publication number: 20100303933Abstract: The present invention relates to an immunopotentiating composition and to a composition accelerating the production of interferon-[gamma]. More particularly to a process for preparation of water-soluble Labisia pumila extract and the use of said extract in a pharmaceutical preparation.Type: ApplicationFiled: November 15, 2007Publication date: December 2, 2010Applicants: HOLISTA BIOTECH SDN. BHD., COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH OF INDIAInventors: Ghulam Nabi Qazi, Sarang Bani, Anpurna Kaull, Anjali Pandey, Kiranjeet Kour, Surrinder Koul, Bishan Dutt Gupta, Pyrelal Sangwan, Ravinder Kumar Raina, Rajendran Manickavasagar
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Patent number: 7794753Abstract: The present invention relates to a synergistic formulation comprising trans-tetracos-15-enoic acid (t-TCA) and andrographolide (AP) in the ratio ranging between 1:7 to 7:1 (w/w), useful in hepatoprotection; and a process for the preparation of a synergistic formulation comprising trans-tetracos-15-enoic acid (t-TCA) and andrographolide (AP) useful in hepatoprotection, said process comprising steps of grounding the particles of the t-TCA and AP into fine particles, mixing the fine particles in ratio ranging between 1:7 to 7:1 (w/w), and grinding the mixture to obtain formulation, and also, a method of hepatoprotection of a subject using the synergistic formulation comprising trans-tetracos-15-enoic acid (t-TCA) and andrographolide (AP), said method comprising the steps of administering the formulation to the subject.Type: GrantFiled: March 31, 2003Date of Patent: September 14, 2010Assignee: Council of Scientific and Industrial ResearchInventors: Vishwa Nath Gupta, Krishan Avtar Suri, Bishan Datt Gupta, Bupinder Singh Jaggi, Naresh Kumar Satti, Bal Krishan Chandan, Neelam Sharma, Vikram Bhardwaj, Om Parkash Suri, Ghulam Nabi Qazi, Jyotsna Suri, Madalsa Bargotra
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Publication number: 20090298938Abstract: The present invention relates to use of compounds of general formula 1 for anticancerous activity, wherein the said compound being derived semi-synthetically from natural triterpenoic acids known as boswellic acids by the induction of apoptosis thereof cytotoxicity and anti-cancer activity displayed by semi-synthetic analogues of natural triterpenes, known as Boswellic acids. These compounds may be used for the treatment of cancer, alone or in combination with pharmaceutically acceptable or other carriers, displaying cytotoxicity and anti-cancer activity for colon, prostrate, liver, breast, central nervous system (CNS), leukemia and malignancy of other tissues, including ascites and solid tumors. The cancer cell death is mediated by induction of apoptosis and inhibition of cell proliferation at specific doses.Type: ApplicationFiled: March 10, 2009Publication date: December 3, 2009Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHInventors: Ghulam Nabi Qazi, Subhash Chandra Taneja, Jaswant Singh, Ajit Kumar Saxena, Vijay Kumar Sethi, Bhahwal Ali Shah, Bal Krishan Kapahi, Samar Singh Andotra, Ajay Kumar, Shashi Bhushan, Fayaz Malik, Dilip Manikrao Mondhe, Shanmugavel Muthiah, Surjeet Singh, Monika Verma, Shashank Kumar Singh
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Patent number: 7514105Abstract: The present invention relates to a bioenhancing/bioavailability-facilitating composition comprising: an effective amount of an extract and/or at least one bioactive fraction from Cuminum cyminum; one or more additive selected from drugs, nutrients, vitamins, nutraceuticals, herbal drugs/products, micro nutrients, antioxidants along with pharmaceuticaly acceptable additives/excipient, and optionally, an effective amount of piperine or extract/fraction of piper nigrum or piper longum; and a process for the preparation of such extracts and active fractions from plant Cuminum cyminum.Type: GrantFiled: February 23, 2006Date of Patent: April 7, 2009Assignee: Council of Scientific and Industrial ResearchInventors: Ghulam Nabi Qazi, Kasturi Lal Bedi, Rakesh Kamal Johri, Manoj Kumar Tikoo, Ashok Kumar Tikoo, Subhash Chander Sharma, Sheikh Tasaduq Abdullah, Om Parkash Suri, Bishan Datt Gupta, Krishan Avtar Suri, Naresh Kumar Satti, Ravi Kant Khajuria, Surjit Singh, Anamika Khajuria, Bal Krishan Kapahi
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Publication number: 20080292736Abstract: The present invention relates to the use of extracts of Carum carvi as bioenhancers, either alone or in combination with piperine or Zingiber officinale extract to improve the bioavailability of a wide variety of drugs.Type: ApplicationFiled: January 28, 2008Publication date: November 27, 2008Inventors: Ghulam Nabi Qazi, Kasturi Lal Bedi, Rakesh Kamal Johri, Manoj Kumar Tikoo, Ashok Kumar Tikoo, Subhash Chandra Sharma, Tasaduaq Abdullah, Om Parkash Suri, Bishan Datt Gupta, Krishan Avtar Suri, Naresh Kumar Satti, Ravi Kant Khajuria
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Publication number: 20080138452Abstract: The present invention relates to a composition useful for hepatocurative effect against CYP 450 bio-activation hepatotoxicity induced by drugs, said composition comprising an extract from Emblica officinalis and optionally pharmaceutically acceptable additives and method of treating drug induced hepatotoxicityType: ApplicationFiled: December 21, 2007Publication date: June 12, 2008Inventors: Rakesh Kamal Johri, Sheikh Tasaduq Abdullah, Kuldeep Singh, Devinder Kumar Gupta, Bal Krishan Kapahi, Dilip Manikrao Mondhe, Satinder Mohan Jain, Om Parkash Suri, Kasturi Lal Bedi, Ghulam Nabi Qazi
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Patent number: 7378268Abstract: The present invention relates to a novel source of microorganism for production of Camptothecin and related camptothecinoids. The invention also discloses its isolation, screening for Camptothecin production, growth, fermentation requirements and chemical analysis of Camptothecin (camptothecinoids).Type: GrantFiled: December 21, 2004Date of Patent: May 27, 2008Assignee: Council Of Scientific & Industrial ResearchInventors: Satish Chander Puri, Vijeshwar Verma, Touseef Amna, Geeta Handa, Vinay Gupta, Neelam Verma, Ravi Kant Khajuria, Ajit Kumar Saxena, Ghulam Nabi Qazi, Michael Spiteller
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Patent number: 7238527Abstract: The present disclosure relates to methods and compositions for in vitro cultivation of species of Swertia, e.g. Swertia chirata (Ham.). The disclosure provides culture media comprising Murashige and Skoog (MS) basal culture medium, plant hormones preferably selected from the group consisting of benzyladenine (BAP), gibberellic acid (GA3), and auxins, and other additives, e.g. sucrose and agar. Preferably, auxins are selected from the group consisting of indole acetic acid (IAA), indole butyric acid (IBA), and naphthalene acetic acid (NAA). Individual plant hormone concentrations are preferably from about 0.5 mg/L to about 5.0 mg/L.Type: GrantFiled: August 13, 2004Date of Patent: July 3, 2007Inventors: Ashok Ahuja, Sushma Koul, Brij Lal Kaul, Navin Kumar Verma, Mahraj Krishen Kaul, Ravinder Kumar Raina, Ghulam Nabi Qazi
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Patent number: 7166728Abstract: The present invention relates to a process for the synthesis of racemic nerol oxide i.e. 3,6-dihydro-4-methyl-2-[2-methyl-1-propenyl)-2H-pyran from monoterpene alcohol nerol i.e. cis-3,7-dimethylocta-2,6-diene-1-ol.Type: GrantFiled: December 28, 2004Date of Patent: January 23, 2007Assignee: Council of Scientific and Industrial ResearchInventors: Vijay Kumar Sethi, Samar Singh Andotra, Subhash Chandra Taneja, Pankaj Gupta, Ghulam Nabi Qazi
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Patent number: 7153983Abstract: The present invention relates to a novel synthetic process for the enriched preparation of substituted R(+)?-benzyl-?-butyrolactone (1) as shown in the drawing wherein R1 and R2 independently or in combination represent the following groups: i.e.Type: GrantFiled: March 3, 2003Date of Patent: December 26, 2006Assignee: Council of Scientific and Industrial ResearchInventors: Subhash Chandra Taneja, Surrinder Kaul, Buddh Singh, Ghulam Nabi Qazi
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Patent number: 7119075Abstract: The present invention relates to the use of bioenhancers to decrease the resistance of microbial strains to anti-infective such an antibiotics and antifungals by potentiating the activities of anti-infective. This may be useful to reduce resistance in bacteria and yeast to aid in the treatment of certain infections and disease and to lower the concentration of antiinfectives necessary to inhibit the growth of microbial strains.Type: GrantFiled: March 31, 2003Date of Patent: October 10, 2006Assignee: Council of Scientific and Industrial ResearchInventors: Ghulam Nabi Qazi, Om Parkash Suri, Kasturi Lal Bedi, Inshad Ali Khan, Vijeshwar Verma, Rakesh Kamal Johri, Krishan Avtar Suri, Bishan Datt Gupta, Naresh Kumar Satti, Manoj Kumar Tikoo, Subhash Chander Sharma, Ashok Kumar Tikoo
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Patent number: 7108870Abstract: The present invention relates to an improved process of analytical and quantitative isolation of withaferin-A from Withania somnifera (Sanskrit: Ashwagandha, English: winter cherry) and other plants and products therefrom, said method comprising steps of selecting most appropriate extraction medium composition, with extraction solvent system consisting of a defined admixture of water and alcohol in a range of proportion of alcohol within a narrow range of (methanol, ethanol etc.Type: GrantFiled: April 13, 2004Date of Patent: September 19, 2006Assignee: Council of Scientific & Industrial ResearchInventors: Rajender Singh Sangwan, Narayan Das Chaurasiya, Laxmi Narayan Misra, Payare Lal, Girish Chandra Uniyal, Neelam Singh Sangwan, Avdhesh Kumar Srivastava, Krishan Avtar Suri, Ghulam Nabi Qazi, Rakesh Tuli