Abstract: Provided are a curcumin nanoparticle complex having a modified particle surface and a method for preparing same. A curcumin nanoparticle complex includes curcumin and phospholipids and has a particle size of less than 1000 nm. A first coating layer containing a cationic material and/or a second coating layer containing an anionic material can be further added.

Abstract: The present invention provides a customized sleep management method performed by a customized sleep management system including a step of collecting a bio-signal by using a computing device; a step of generating user sleep data by performing a pre-processing process on the collected bio-signal; a step of classifying sleep steps by using a sleep analysis model receiving the user sleep data and detecting sleep disorder appearing in the classified sleep steps; and a step of providing customized stimulation for alleviating the detected sleep disorder. The bio-signal includes at least one of an electrophysiological signal and a non-electrophysiological signal.