Patents by Inventor Gia-fen T. Chen

Gia-fen T. Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Control of the synthesis of proteins by anitisense RNA-tRNA complex
    Patent number: 5821052
    Abstract: The inhibition of proteins synthesis by an antisense RNA-tRNA complex which is capable of inhibiting translation is described. Under certain conditions, growth of organisms is inhibited by inhibition of non-specific translation by an antisense RNA construct to a tRNA target. In vitro, cell-free inhibition of viral protein translation is described. Transformed microorganisms are disclosed. The invention has applicability in the control of cell growth, such as viruses, bacteria, infected cells, or tumor cells. The invention is useful in animal and plant fields.
    Type: Grant
    Filed: November 28, 1994
    Date of Patent: October 13, 1998
    Assignee: University of Medicine and Dentistry of New Jersey
    Inventors: Gia-fen T. Chen, Oleg Mirochnitchenko, Masayori Inouye