Patents by Inventor Giacomo Bruno

Giacomo Bruno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for purifying thioctic acid in water
    Patent number: 7547792
    Abstract: Process for purifying thioctic acid in water comprising the following steps: a) dissolving the thioctic acid in an aqueous alkaline solution or alternatively dissolving a thioctic acid salt, if necessary adjusting the pH to alkaline values, b) acidifying the solution from step (a) with an acid chosen from the class consisting of sulfuric acid, phosphoric acid, methanesulfonic acid to a pH between 5.4 and 5.8. c) isolating the thioctic acid precipitated in step (b) by conventional methods.
    Type: Grant
    Filed: March 21, 2006
    Date of Patent: June 16, 2009
    Assignee: Laboratorio Chimico Internazionale S.p.A.
    Inventors: Annibale Salvi, Antonio Nardi, Giacomo Bruno
  • Process For Purifying Thioctic Acid in Water
    Publication number: 20080227990
    Abstract: Process for purifying thioctic acid in water comprising the following steps: a) dissolving the thioctic acid in an aqueous alkaline solution or alternatively dissolving a thioctic acid salt, if necessary adjusting the pH to alkaline values, b) acidifying the solution from step (a) with an acid chosen from the class consisting of sulfuric acid, phosphoric acid, methanesulfonic acid to a pH between 5.4 and 5.8. c) isolating the thioctic acid precipitated in step (b) by conventional methods.
    Type: Application
    Filed: March 21, 2006
    Publication date: September 18, 2008
    Applicant: LABORATORIO CHIMICO INTERNAZIONALE S.p.A.
    Inventors: Annibale Salvi, Antonio Nardi, Giacomo Bruno
  • Process for the preparation of metaxalone
    Patent number: 6538142
    Abstract: A process for the preparation of 5-(3,5-dimethylphenoxymethyl)-2-oxazolidinone, which includes: a) reacting 3,5-dimethylphonel with epichlorohydrin to obtain a mixture of 1-(3,5-dimethylphenoxy)2,3-epoxy propane (1) and 1-(3,5-dimethylphenoxy)-3-chloro-2-propanol (2); b) reacting the mixture of (1) and (2) obtained from step (a) with benzylamine to obtain a first compound; c) reducing the first compound with hydrogen in presence of ammonia, to obtain a second compound; and d) reacting the second compound with dimethylcarbonate in the presence of a strong base to obtain 5-(3,5-dimethlphenoxymethyl)-2-oxazolidinone.
    Type: Grant
    Filed: April 18, 2002
    Date of Patent: March 25, 2003
    Assignee: Farchemia S.r.l.
    Inventors: Gabriele Breviglieri, Sergio Contrini, Giacomo Bruno, Cinzia Assanelli
  • 5-CYANO-10-HYDROXY-10,11-DIHYDRO-5H-DIBENZ[B,F]AZEPINE, THE PROCESSES FOR ITS PREPARATION AND FOR ITS CONVERSION INTO 5-CARBAMOYL-10-OXO-10, 11-DIHYDRO-5H-DIBENZ[B,F]AZEPINE OR INTO 5-CARBAMOYL-5H-DIBENZ[B,F]AZEPINE
    Patent number: 6384217
    Abstract: 5-Cyano-10-Hydroxy-10,11-Dihydro-5H-Dibenzi[b,f]azepine and the process for its preparation.
    Type: Grant
    Filed: February 17, 2001
    Date of Patent: May 7, 2002
    Assignee: Farchemia S.R.L.
    Inventors: Citterio Attilio, Breviglieri Gabriele, Giacomo Bruno
  • Process for the preparation of 4.5-diphenyloxazole-2-propanoic acid
    Patent number: 6096896
    Abstract: In a process for the preparation of 4,5-diphenyloxazole-2-propanoic acid, the improvement consisting in using toluene in the esterification reaction of benzoin, and acetic acid/formic acid in the subsequent cyclization, thereby obtaining higher yields and avoiding the use and the disposal of high amounts of pyridine.
    Type: Grant
    Filed: October 15, 1998
    Date of Patent: August 1, 2000
    Assignee: Farchemia s.r.l.
    Inventors: Gabriele Breviglieri, Giacomo Bruno, Sergio Contrini, Cinzia Assanelli