Patents by Inventor Gian F. Tamagnone

Gian F. Tamagnone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the synthesis of pyrido-imidazo rifamycins
    Patent number: 4557866
    Abstract: A new process for the synthesis of pyrido-imidazo-rifamycins of formula ##STR1## wherein R is hydrogen or acetyl, R.sub.1 and R.sub.2 independently represent hydrogen, (C.sub.1-4)-alkyl, benzyloxy, mono- or di-(C.sub.1-3)-alkylamino-(C.sub.1-4)-alkyl, (C.sub.1-3)-alkoxy-(C.sub.1-4)-alkyl, hydroxymethyl, hydroxy-(C.sub.2-4)-alkyl, cyano, halogen, nitro, mercapto, (C.sub.1-4)-alkylthio, phenylthio, carbamoyl, mono- or di-(C.sub.1-4)-alkyl-carbamoyl, or R.sub.1 and R.sub.2 taken together with two consecutive carbon atoms of the pyridine nucleus form a benzene ring optionally substituted by one or two methyl or ethyl groups.The process comprises reacting the rifamycin O of formula ##STR2## with a 2-aminopyridine of formula ##STR3## wherein R.sub.1 and R.sub.2 have the same meanings as before.
    Type: Grant
    Filed: April 26, 1985
    Date of Patent: December 10, 1985
    Assignee: ALFA Farmaceutici S.p.a.
    Inventors: Vincenzo Cannata, Gian F. Tamagnone