Patents by Inventor GIAN FRANCO PIREDDA

GIAN FRANCO PIREDDA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12217426
    Abstract: A system and a method for measuring a maturation stage of a biological organ are based on quantitative MR maps for the organ. The method includes acquiring with a first interface and for a subject, a quantitative MR map for the organ. The quantitative MR map includes voxels each characterized by a quantitative value. The quantitative value of each voxel represents a measurement of a physical or physiological property of a tissue of the biological organ for the voxel. The method also includes applying to the quantitative map a trained function to estimate the subject organ maturation stage, and the trained function outputting an age. The method provides with a second interface the maturation stage of the organ of the subject as being the output age.
    Type: Grant
    Filed: March 22, 2021
    Date of Patent: February 4, 2025
    Assignee: Siemens Healthineers AG
    Inventors: Gian Franco Piredda, Tobias Kober, Tom Hilbert, Lars Lauer
  • Publication number: 20240338819
    Abstract: A system and a method for detecting and quantifying a tissue alteration of a biological object. The method comprises the following steps: acquiring multiple quantitative maps of the biological object, wherein each of the multiple quantitative maps is a quantitative map of a different physical tissue property of the biological object; combining the acquired quantitative maps into a combined quantitative map (CQM); and calculating a deviation map by comparing the CQM to a normative atlas configured for providing expected values for the CQM.
    Type: Application
    Filed: April 4, 2024
    Publication date: October 10, 2024
    Inventors: Tom Hilbert, Tobias Kober, Gian Franco Piredda, Veronica Ravano
  • Publication number: 20230320610
    Abstract: A system and a method for mapping brain tissue damage from quantitative imaging data. The method is implemented by acquiring a quantitative map of a brain tissue parameter of said brain; acquiring a tractography map for said brain; superimposing a first map based on the quantitative map onto a second map based on the tractography map. Metrics are extracted from the superimposition that reflect a distribution of tract-specific quantitative values of the brain tissue parameter and the metrics of the brain are displayed.
    Type: Application
    Filed: April 8, 2022
    Publication date: October 12, 2023
    Inventors: Veronica Ravano, Gian Franco Piredda, Tom Hilbert, Tobias Kober, Jonas Richiardi
  • Publication number: 20210295521
    Abstract: A system and a method for measuring a maturation stage of a biological organ are based on quantitative MR maps for the organ. The method includes acquiring with a first interface and for a subject, a quantitative MR map for the organ. The quantitative MR map includes voxels each characterized by a quantitative value. The quantitative value of each voxel represents a measurement of a physical or physiological property of a tissue of the biological organ for the voxel. The method also includes applying to the quantitative map a trained function to estimate the subject organ maturation stage, and the trained function outputting an age. The method provides with a second interface the maturation stage of the organ of the subject as being the output age.
    Type: Application
    Filed: March 22, 2021
    Publication date: September 23, 2021
    Inventors: GIAN FRANCO PIREDDA, TOBIAS KOBER, TOM HILBERT, LARS LAUER
  • Patent number: 10657410
    Abstract: Organ tissue properties of a patient are automatically compared with organ tissue properties of a healthy subject group. A population norm for the organ tissue properties is determined by: selecting at least two different tissue properties of the organ; determining for each tissue property previously selected and for each subject of said group a quantitative tissue property map; for each subject of the group, calculating a joint histogram from all the quantitative tissue property maps obtained for said subject; and determining an averaged joint histogram from all subjects of the healthy group, thus defining the population norm. A comparison is automatically performed of the averaged joint histogram with a patient joint histogram obtained for the organ tissue properties of the patient, by calculating a statistical deviation of values of a patient joint histogram relative to values of the averaged joint histogram, and mapping the statistical deviation to the patient organ.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: May 19, 2020
    Assignee: Siemens Healthcare GmbH
    Inventors: Tom Hilbert, Tobias Kober, Gian Franco Piredda
  • Publication number: 20190318197
    Abstract: Organ tissue properties of a patient are automatically compared with organ tissue properties of a healthy subject group. A population norm for the organ tissue properties is determined by: selecting at least two different tissue properties of the organ; determining for each tissue property previously selected and for each subject of said group a quantitative tissue property map; for each subject of the group, calculating a joint histogram from all the quantitative tissue property maps obtained for said subject; and determining an averaged joint histogram from all subjects of the healthy group, thus defining the population norm. A comparison is automatically performed of the averaged joint histogram with a patient joint histogram obtained for the organ tissue properties of the patient, by calculating a statistical deviation of values of a patient joint histogram relative to values of the averaged joint histogram, and mapping the statistical deviation to the patient organ.
    Type: Application
    Filed: April 13, 2018
    Publication date: October 17, 2019
    Inventors: TOM HILBERT, TOBIAS KOBER, GIAN FRANCO PIREDDA