Abstract: Activation of senescent stem cells in humans to promote wound healing and other therapies, and to promote general enhancement of health by application of non-thermal atmospheric pressure plasma (NTAPP) to tissues and body fluids such as blood. In particular, the targets of the NTAPP are stem cells. The products contained in NTAPP can affect the behavior of peripheral blood stem cells (PBSC) in blood, as well as stem cells found in tissues surrounding the blood in which said products are carried.