Patents by Inventor Giancarlo Santus

Giancarlo Santus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10292951
    Abstract: This disclosure features chemical entities (e.g., a compound exhibiting activity as a mitochondrial uncoupling agent or a pharmaceutically acceptable salt and/or hydrate and/or cocrystal thereof; e.g., a compound, such as niclosamide or a pharmaceutically acceptable salt and/or hydrate and/or cocrystal thereof; e.g., a compound, such as a niclosamide analog, or a pharmaceutically acceptable salt and/or hydrate and/or cocrystal thereof) that are useful, e.g., for treating one or more symptoms of a pathology characterized by an abnormal inflammatory response (e.g., inflammatory bowel diseases) in a subject (e.g., a human). This disclosure also features compositions as well as other methods of using and making the same.
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: May 21, 2019
    Assignee: First Wave Bio, Inc.
    Inventors: Gary D. Glick, Luigi Franchi, Giancarlo Santus
  • Publication number: 20180362456
    Abstract: The present invention describes new derivatives of S-allylcysteine with antioxidant and antiaging activity. Said derivatives can be used alone or in a combined formulation with other compounds with known activity.
    Type: Application
    Filed: December 6, 2016
    Publication date: December 20, 2018
    Inventors: Giancarlo SANTUS, Silvana MASIERO, Leticia Khater COVESI
  • Patent number: 10086002
    Abstract: The present invention describes novel and improved dosage forms containing fluticasone propionate for the treatment of conditions associated with inflammation of the esophagus.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: October 2, 2018
    Assignee: EMS S.A.
    Inventors: Giancarlo Santus, Leticia Khater Covesi, Luca Donadoni, Christina Ecclissato, Roberto Amazonas
  • Publication number: 20180235979
    Abstract: The present invention describes novel and improved dosage forms containing fluticasone propionate for the treatment of conditions associated with inflammation of the esophagus.
    Type: Application
    Filed: April 23, 2018
    Publication date: August 23, 2018
    Inventors: Giancarlo SANTUS, Leticia Khater COVESI, Luca DONADONI, Christina ECCLISSATO, Roberto AMAZONAS
  • Patent number: 9980975
    Abstract: The present invention describes novel and improved dosage forms containing fluticasone propionate for the treatment of conditions associated with inflammation of the esophagus.
    Type: Grant
    Filed: January 22, 2015
    Date of Patent: May 29, 2018
    Assignee: EMS S.A.
    Inventors: Giancarlo Santus, Leticia Khater Covesi, Luca Donadoni, Christina Ecclissato, Roberto Amazonas
  • Publication number: 20170266202
    Abstract: The present invention describes novel and improved dosage forms containing fluticasone propionate for the treatment of conditions associated with inflammation of the esophagus.
    Type: Application
    Filed: June 2, 2017
    Publication date: September 21, 2017
    Inventors: Giancarlo SANTUS, Leticia Khater COVESI, Luca DONADONI, Christina ECCLISSATO, Roberto AMAZONAS
  • Publication number: 20160213681
    Abstract: The present invention describes novel and improved dosage forms containing fluticasone propionate for the treatment of conditions associated with inflammation of the esophagus.
    Type: Application
    Filed: January 22, 2015
    Publication date: July 28, 2016
    Inventors: Giancarlo SANTUS, Leticia Khater COVESI, Luca DONADONI, Christina ECCLISSATO, Roberto AMAZONAS
  • Publication number: 20150110885
    Abstract: The present invention describes novel and improved parenteral depot pharmaceutical compositions containing cosyntropin (tetracosactide), for the treatment of infantile spasm.
    Type: Application
    Filed: October 17, 2014
    Publication date: April 23, 2015
    Inventors: Giancarlo SANTUS, Luca DONADONI, Leticia Khater COVESI
  • Publication number: 20150044284
    Abstract: The present invention describes new and improved dosage forms containing a steroid 5-alpha-reductase inhibitor, in combination with an alpha blocker, for the treatment or prophylaxis of an androgen mediated disease or condition, preferably for the treatment of benign prostatic hyperplasia (HPB).
    Type: Application
    Filed: August 11, 2014
    Publication date: February 12, 2015
    Inventors: Giancarlos SANTUS, Giuseppe Soldati, Luca Donadoni
  • Publication number: 20140314848
    Abstract: The present invention describes antihypertensive pharmaceutical formulations particularly formulations of losartan and indapamide.
    Type: Application
    Filed: October 2, 2012
    Publication date: October 23, 2014
    Inventors: Giuseppe Soldati, Giancarlo Santus, Ricardo Vian Marques, Leticia Khater Covesi, Pedro Bordeaux Rego
  • Publication number: 20130273114
    Abstract: The present invention describes immunosuppressant pharmaceutical formulations particularly formulations of mycophenolate salts with pulsatile release behaviour.
    Type: Application
    Filed: January 18, 2012
    Publication date: October 17, 2013
    Applicant: EMS S.A.
    Inventors: Giancarlo Santus, Giuseppe Soldati
  • Publication number: 20100217028
    Abstract: The present invention refers to a process for preparing a compound of general formula (A), as reported in the description, wherein R is a radical of a drug and R1-R12 are hydrogen or alkyl groups, m, n, o, q, r and s are each independently an integer from 0 to 6, and p is 0 or 1, and X is O, S, SO, SO2, NR13 or PR13 or an aryl, heteroaryl group, said process comprising reacting a compound of formula (B) R—COOZ (B) wherein R is as defined above and Z is hydrogen or a cation selected from: Li+, Na+, K+, Ca++, Mg++, tetralkylammonium, tetralkylphosphonium, with a compound of formula (C), as reported in the description, wherein R1-R12 and m, n, o, p, q, r, s are as defined above and Y is a suitable leaving group.
    Type: Application
    Filed: March 30, 2010
    Publication date: August 26, 2010
    Applicant: NICOX S.A.
    Inventors: Piero DEL SOLDATO, Giancarlo SANTUS, Francesca BENEDINI
  • Patent number: 7776902
    Abstract: New compounds able to release COX-2 inhibitors and NO having formula (I): M-T-YA—NO2??(I) for the treatment and/or prophylaxis of inflammatory processes.
    Type: Grant
    Filed: June 20, 2003
    Date of Patent: August 17, 2010
    Assignee: Nicox S.A.
    Inventors: Piero Del Soldato, Giancarlo Santus
  • Publication number: 20100168216
    Abstract: The present invention relates to new prostaglandin derivatives having improved pharmacological activity and enhanced tolerability. They can be employed for the treatment of glaucoma and ocular hypertension.
    Type: Application
    Filed: March 6, 2008
    Publication date: July 1, 2010
    Applicant: CTG PHARMA S.R.L.
    Inventors: Piero Del Soldato, Giancarlo Santus, Anna Sparatore
  • Patent number: 7723382
    Abstract: The present invention refers to a process for preparing a compound of general formula (A), as reported in the description, wherein R is a radical of a drug and R1-R12 are hydrogen or alkyl groups, m, n, o, q, r and s are each independently an integer from 0 to 6, and p is 0 or 1, and X is O, S, SO, SO2, NR13 or PR13 or an aryl, heteroaryl group, said process comprising reacting a compound of formula (B) R—COOZ (B) wherein R is as defined above and Z is hydrogen or a cation selected from: Li+, Na+, K+, Ca++, Mg++, tetralkylammonium, tetralkylphosphonium, with a compound of formula (C), as reported in the description, wherein R1-R12 and m, n, o, p, q, r, s are as defined above and Y is a suitable leaving group.
    Type: Grant
    Filed: August 6, 2003
    Date of Patent: May 25, 2010
    Assignee: Nicox S.A.
    Inventors: Piero del Soldato, Giancarlo Santus, Francesca Benedini
  • Publication number: 20090017003
    Abstract: The present invention relates to novel thiosulfonates derivatives. The present invention also provides methods for preventing, treating and/or reducing inflammation-associated diseases in the cardiovascular, connective tissue, pulmonary, gastrointestinal, respiratory, urogenital, nervous or cutaneous systems as well as infective and tumoral diseases employing said compounds.
    Type: Application
    Filed: March 1, 2007
    Publication date: January 15, 2009
    Applicant: SULFIDRIS S.R.L.
    Inventors: Piero Del Soldato, Giancarlo Santus, Anna Sparatore
  • Patent number: 7476689
    Abstract: An analgesic/anti-inflammatory pharmaceutical dosage form which comprises an effective amount of an active ingredient selected from the group consisting of racemic 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, optically active forms thereof and pharmaceutically acceptable salts thereof, in combination with a pharmaceutically acceptable excipient or diluent, said dosage form being an intranasally administrable dosage form.
    Type: Grant
    Filed: March 2, 2004
    Date of Patent: January 13, 2009
    Assignee: Recordati Ireland Limited
    Inventors: Giancarlo Santus, Giuseppe Bottoni, Ettore Bilato
  • Patent number: 7267827
    Abstract: An analgesic/anti-inflammatory pharmaceutical dosage form which comprises an effective amount of an active ingredient selected from the group consisting of racemic 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, optically active forms thereof and pharmaceutically acceptable salts thereof, in combination with a pharmaceutically acceptable excipient or diluent, said dosage form being an intranasally administrable dosage form.
    Type: Grant
    Filed: July 13, 2001
    Date of Patent: September 11, 2007
    Assignee: Recordati S.A.
    Inventors: Giancarlo Santus, Giuseppe Bottoni, Ettore Bilato
  • Publication number: 20070112194
    Abstract: The present invention refers to a process for preparing a compound of general formula (A), as reported in the description, wherein R is a radical of a drug and R1-R12 are hydrogen or alkyl groups, m, n, o, q, r and s are each independently an integer from 0 to 6, and p is 0 or 1, and X is O, S, SO, SO2, NR13 or PR13 or an aryl, heteroaryl group, said process comprising reacting a compound of formula (B) R—COOZ (B) wherein R is as defined above and Z is hydrogen or a cation selected from: Li+, Na+, K+, Ca++, Mg++, tetralkylammonium, tetralkylphosphonium, with a compound of formula (C), as reported in the description, wherein R1-R12 and m, n, o, p, q, r, s are as defined above and Y is a suitable leaving group.
    Type: Application
    Filed: August 6, 2003
    Publication date: May 17, 2007
    Inventors: Piero Del Soldato, Giancarlo Santus, Francesca Benedini
  • Patent number: 7199258
    Abstract: The present invention refers to a process for preparing a compound of general formula (A), as reported in the description, wherein R is a radical of naproxen or bromonaproxen and R1–R12 are hydrogen or alkyl groups, m, n, o, q, r and s are each independently an integer from 0 to 6, and p is 0 or 1, and and X is O, S, SO, SO2, NR13 or PR13 or an aryl, heteroaryl group, said process comprising reacting a compound of formula (B) R—COOZ??(B) wherein R is as defined above and Z is hydrogen or a cation selected from: Li+, Na+, K+, Ca++, Mg++, tetralkylammonium, tetralkylphosphonium, with a compound of formula (C), as reported in the description, wherein R1–R12 and m, n, o, p, q, r, s are as defined above and Y is a suitable leaving group.
    Type: Grant
    Filed: August 6, 2003
    Date of Patent: April 3, 2007
    Assignee: Nicox S.A.
    Inventors: Piero Del Soldato, Giancarlo Santus, Francesca Benedini