Abstract: Compounds of the formula (I) ##STR1## wherein R.sub.1 is:(a) hydrogen, or C.sub.1 -C.sub.6 alkyl;(b) an unsubstituted 2-pyridyl or 3-pyridyl group;(c) a benzyl group, wherein the phenyl ring is unsubstituted or substituted by halogen, C.sub.1 -C.sub.6 alkoxy or C.sub.1 -C.sub.6 alkyl;(d) a phenyl ring, unsubstituted or substituted by one or two groups chosen from halogen, trihalomethyl, C.sub.1 -C.sub.6 alkoxy, C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.6 alkanoylamino, nitro and amino;each of R.sub.2 and R.sub.3 independently represents hydrogen, halogen or C.sub.1 -C.sub.6 alkyl;R.sub.4 represents a 2-pyridyl, 3-pyridyl or 4-pyridyl group, unsubstituted or substituted by C.sub.1 -C.sub.6 alkyl;and the pharmaceutically acceptable salts thereof are disclosed. The compounds have activity in the gastroenteric system, particularly anti-ulcerogenic and gastric anti-secretory activity.

Abstract: Compounds of general formula (I) ##STR1## wherein R.sub.1 is a 2-pyridyl, 3-pyridyl or 4-pyridyl group; (b) a phenyl ring, unsubstituted or substituted by one or two groups chosen from halogen, trihalo-C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.6 alkyl, nitro, amino and C.sub.2 -C.sub.6 alkanoylamino; (c) benzyl; or (d) C.sub.1 -C.sub.6 alkyl;each of R.sub.2 and R.sub.3 independently is a hydrogen or a halogen atom or C.sub.1 -C.sub.6 alkyl;R.sub.4 is hydrogen, C.sub.1 -C.sub.6 alkyl or phenyl;R.sub.5 is (a') ##STR2## wherein each of R.sub.6 and R.sub.7 independently is hydrogen or C.sub.1 -C.sub.6 alkyl, or R.sub.6 and R.sub.7, taken together with the nitrogen atom to which they are linked, form a morpholino, piperidino, N-pyrrolidinyl or N-piperazinyl ring, wherein the N-piperazinyl ring is unsubstituted or substituted by C.sub.1 -C.sub.6 alkyl;(b') a ##STR3## wherein R.sub.8 is hydrogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy or halogen;(c') --NHR.sub.9, wherein R.sub.

Abstract: Pharmacologically active thiazolo[3,2-a]pyrimidines of the formula ##STR1## wherein A is a bond between the .alpha. and .beta.-carbon atoms or (--CH.sub.2 --) group; R.sub.1 and R.sub.2 represent hydrogen or halogen, C.sub.1 -C.sub.4 alkyl, cyano, CF.sub.3, thienyl, pyridyl, biphenyl, naphtyl, phenyl optionally substituted, ##STR2## wherein R' and R" are hydrogen or alkyl; R.sub.3 represents hydrogen, halogen, alkyl, OH, formyloxy, alkanoyloxy, alkenyloxy; R.sub.4 represents pyridyl optionally substituted by alkyl. The compounds have antiinflammatory, antiulcerogenic and anti-gastric secretory activity.

Abstract: Substituted Pyrrolo [2,1-b] and Pyrido [2, 1 b] Quinazolines are provided, together with pharmaceutical compositions, containing them. The compounds have pharmaceutical utility, and are particularly useful for the treatment of or prevention of the formation of gastrointestinal ulcers.

Abstract: Substituted pyrido [1,2-a] pyrimidines and pharmaceutical compositions containing them, suitable for use as anti-allergy, anti-ulcer, and anti-diabetic agents.

Abstract: The present invention relates to substituted 2-(pyridyl-cyclopropyl)-chromones, to a process for their preparation and to pharmaceutical compositions containing them.

Abstract: Substituted 6,7-methylen[1,2-a]pyrimidines and pharmaceutical compositions containing them, suitable for use as anti-allergic, anti-ulcer and anti-diabetic agents.

Abstract: 3,4-Dihydro-quinazoline derivatives, such as 6-carboxy-2-(2'-ethoxy-phenyl)-3,4-dihydro-4-oxo-quinazoline, are disclosed. The compounds possess anti-allergy properties and can be used for the treatment of allergic conditions.

Abstract: Substituted 2-vinyl chromones are disclosed, wherein the chromone ring has an alkyl or alkenyl substituent at the 3-position, and a styryl substituent at the 2-position. The compounds exhibit anti-allergy activity and can be used to treat allergic conditions.

Abstract: Substituted 2-vinyl-chromones are disclosed, wherein the chromone ring has an alkyl or alkenyl substituent at the 3-position, and a styryl substituent at the 2-position. The compounds exhibit anti-allergy activity and can be used to treat allergic conditions.

Abstract: Substituted 2-vinyl chromones are disclosed, wherein the chromone ring has an alkyl or alkenyl substituent at the 3-position, and an unsubstituted furyl substituent at the 2-position. The compounds exhibit anti-allergy activity and can be used to treat allergic conditions.

Abstract: Substituted 2-vinyl chromones are disclosed, wherein the chromone ring has an alkyl or alkenyl substituent at the 3-position, and a pyridyl-vinyl substituent at the 2-position. The compounds exhibit anti-allergy activity and can be used to treat allergic conditions.

Abstract: Substituted 2-cyclopropylchromones, process of preparation, pharmaceutical compositions and method of treating allergies are disclosed.

Abstract: 3,4-Dihydro-4-oxo-quinazoline derivatives substituted in the 2-position by a substituted phenyl group are disclosed. The derivatives possess anti-allergy properties and can be used for the treatment of allergic conditions.

Abstract: 6-CARBOXY-FLAVONE DERIVATIVES ARE DISCLOSED, WHEREIN THE FLAVONE DERIVATIVE IS SUBSTITUTED AT THE 2'-POSITION WITH AN ALKOXY GROUP, WHICH MAY BE SUBSTITUTED, AND WHEREIN THE PHENYL RING ALSO CARRIES AN ALKYL SUBSTITUENT.The flavone derivatives exhibit anti-allergic activity and spasmolytic activity.

Abstract: Substituted 2-vinyl-chromones are disclosed wherein the chromone ring has an alkyl or alkenyl substituent at the 3-position. The compounds exhibit anti-allergy activity and can be used to treat allergic conditions.

Abstract: Chromone compounds carrying a pyridyl substituent at the 2-position are disclosed, such as, for instance, 6-carboxy-2-(2'-pyridyl)-chromone. The disclosed compounds are useful in the treatment of allergies.

Abstract: 8,12-Diisoprostanoic acid compounds and intermediates useful in the processes of making them have been prepared.

Abstract: Chromone compounds carrying a pyrazinyl substituent at the 2-position are disclosed, such as, for instance, 6-carboxy-2-(2'-pyrazinyl)-chromone.The disclosed compounds are useful in the treatment of allergies.

Abstract: Optically active 8,12-diisoprostanoic acids and derivatives, processes for making same, pharmaceutical compositions containing same, and intermediates for producing same are disclosed. The acids include, for instance, 5c,13t-11.alpha.,15S-dihydroxy-9-oxo-8,12-diisoprostadienoic acid. The compounds of the present invention can be used in the same uses as the natural prostaglandins, including the treatment of asthma, parturition to facilitate child bearing labor and as abortion agents.