Patents by Inventor Gianfranco de Paoli Ambrosi

Gianfranco de Paoli Ambrosi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9511112
    Abstract: The present invention relates to an antibacterial composition, preferably for topical use, comprising triethyl citrate and a peptide consisting of 15 amino acids of sequence FAKALKALLKALKAL-NH2 (SEQ ID NO: 1), wherein F is phenylalanine, A is alanine, K is lysine and L is leucine, particularly for the treatment of acne, suppurative or non-suppurative hidradenitis, atopic dermatitis characterized by colonization by Staphylococcus Aureus, impetigo, interdigital infections, folliculitis, boils, post-traumatic infections, and burned skin infections.
    Type: Grant
    Filed: July 29, 2013
    Date of Patent: December 6, 2016
    Assignee: GENERAL TOPICS S.R.L.
    Inventor: Gianfranco de Paoli Ambrosi
  • Patent number: 9475887
    Abstract: A novel compound is disclosed, said compound comprising hyaluronic acid, optionally cross-linked, or an oligomer, optionally cross-linked, dimer or monomer thereof, which is salified or at least partially salified with carnosine, wherein the carnosine is in the form of an L- or D-enantiomer or a racemate; a process for producing this compound, its cosmetic and therapeutic use as well as pharmaceutical and cosmetic compositions containing the same are also disclosed.
    Type: Grant
    Filed: December 6, 2011
    Date of Patent: October 25, 2016
    Inventor: Gianfranco De Paoli Ambrosi
  • Publication number: 20150209405
    Abstract: The present invention relates to an antibacterial composition, preferably for topical use, comprising triethyl citrate and a peptide consisting of 15 amino acids of sequence FAKALKALLKALKAL-NH2, wherein F is phenylalanine, A is alanine, K is lysine and L is leucine, particularly for the treatment of acne, suppurative or non-suppurative hidradenitis, atopic dermatitis characterized by colonization by Staphylococcus Aureus, impetigo, interdigital infections, folliculitis, boils, post-traumatic infections, and burned skin infections.
    Type: Application
    Filed: July 29, 2013
    Publication date: July 30, 2015
    Applicant: GENERAL TOPICS S.r.l.
    Inventor: Gianfranco de Paoli Ambrosi
  • Publication number: 20150148393
    Abstract: The invention relates to a cosmetic and/or pharmaceutical composition in combination with suitable carriers for topical use, comprising a mixture consisting of methyl sulfonyl methane and at least one compound belonging to the class of 4-alkyl cyclohexanols, which is useful in the treatment of various inflammatory conditions such as rosacea. The composition can act to simultaneously hinder both the release of chemical mediators which are up-regulated in rosacea and their action of causing the activation of TRPV receptors. The composition can reduce the effect of ultraviolet radiations on a skin already affected by an inflammatory process, and particularly, it can reduce the erythema induced by ultraviolet radiations on a skin already affected by an inflammatory process.
    Type: Application
    Filed: June 4, 2013
    Publication date: May 28, 2015
    Applicant: GENERAL TOPICS S.R.L.
    Inventor: Gianfranco De Paoli Ambrosi
  • Publication number: 20150110725
    Abstract: The present invention relates to a mixture comprising acetylglucosamine and 4-(1-phenylethyl)-1,3-benzenediol for use as a cosmetic and/or medicament, and particularly for the inhibition of melanin biosynthesis, and to a cosmetic and/or pharmaceutical formulation comprising such a mixture for the treatment of hyperpigmented lesions of the skin such as, for example but without limitation, lentigo solaris, age spots, melasma and chloasma, for rendering uniform the color of the skin, for counteracting the formation of free radicals, and for counteracting or preventing signs of skin aging such as wrinkles and lack of skin tone, and generally for improving the aesthetic conditions of the skin.
    Type: Application
    Filed: June 4, 2013
    Publication date: April 23, 2015
    Applicant: GENERAL TOPICS S.R.L.
    Inventor: Gianfranco De Paoli Ambrosi
  • Publication number: 20140303116
    Abstract: A novel compound is disclosed, said compound comprising hyaluronic acid, optionally cross-linked, or an oligomer, optionally cross-linked, dimer or monomer thereof, which is salified or at least partially salified with carnosine, wherein the carnosine is in the form of an L- or D-enantiomer or a racemate; a process for producing this compound, its cosmetic and therapeutic use as well as pharmaceutical and cosmetic compositions containing the same are also disclosed.
    Type: Application
    Filed: December 6, 2011
    Publication date: October 9, 2014
    Inventor: Gianfranco De Paoli Ambrosi
  • Publication number: 20140221474
    Abstract: A chemical peeling formulation and a formulation able to increase the efficacy and the tolerability of preparations based on the use of compounds used to carry out chemical peeling, comprising at least one keratolytic agent and dimethyl isosorbide. The composition may additionally comprise dimethyl sulphone.
    Type: Application
    Filed: February 24, 2014
    Publication date: August 7, 2014
    Inventor: Gianfranco de Paoli Ambrosi
  • Publication number: 20120094965
    Abstract: A chemical peeling formulation and a formulation able to increase the efficacy and the tolerability of preparations based on the use of compounds used to carry out chemical peeling, comprising at least one keratolytic agent and dimethyl isosorbide. The composition may additionally comprise dimethyl sulphone.
    Type: Application
    Filed: April 19, 2011
    Publication date: April 19, 2012
    Inventor: Gianfranco de Paoli Ambrosi
  • Publication number: 20100267663
    Abstract: This invention concerns a composition for pharmaceutical and/or cosmetic and/or in the form of medical device, in particular for the prevention and treatment of hypertrophic scars and/or cheloids, to inhibit any fibrosclerotic process and to improve the biomechanical properties of the skin and to obstruct retraction to cicatrisation of the skin, as it contains, as an active ingredient, at least one of the active principles chosen between fucose (and/or Fucose rich polysaccharides—FROPs), Dimethyl sulfone and acetyl glucosamine.
    Type: Application
    Filed: October 30, 2008
    Publication date: October 21, 2010
    Inventor: Gianfranco de Paoli Ambrosi
  • Publication number: 20100261794
    Abstract: This invention concerns a cosmetic composition for topical use containing as an active principle a blend of arginine and taurine designed to carry out an immediate “lifting” effect and able to improve in a short time the aesthetic characteristics of the cutis. The composition contains a quantity in weight of arginine of 0.05% p/p at 90% p/p, preferably from 0.5% p/p to 5% p/p, and a quantity in weight of taurine from 0.05% p/p to 90% p/p, preferably from 0.5% p/p to 5% p/p.
    Type: Application
    Filed: October 30, 2008
    Publication date: October 14, 2010
    Inventor: Gianfranco de Paoli Ambrosi
  • Publication number: 20100069490
    Abstract: The invention proposes a composition for pharmaceutical use containing as active principles triethyl citrate and adapalene in quantities efficacious for use in the treatment of cutaneous pathologies of inflammatory origin, caused by bacterial infections or altered lipid metabolism, both in the treatment of chronologic and photo induced cutaneous ageing,
    Type: Application
    Filed: November 5, 2007
    Publication date: March 18, 2010
    Inventor: Gianfranco de Paoli Ambrosi
  • Publication number: 20080287377
    Abstract: The invention concerns a composition for topical use for the protection of triglycerides against enzymatic hydrolysis, which contains triethyl citrate as an active ingredient either pure or in combination with some synergists. The triethyl citrate is in a quantity in weight expressed as a percentage from 0.1 to 99.9, preferably from 0.2 to 50 percent or even better a weight expressed as a percentage from 1.0 to 25.0. The claims are also directed to the use of triethylcitrate for the treatment of acne and seborrheic dermatitis, for the protection of triglycerides in alimentary products and for treatment of aesthetic cutaneous effects in the cosmic field.
    Type: Application
    Filed: November 29, 2006
    Publication date: November 20, 2008
    Inventor: Gianfranco de Paoli Ambrosi
  • Publication number: 20080286031
    Abstract: The invention concerns a device for dispensing doses of fluid substances with different viscosities or densities, comprising a container (11), a piston (25) housed and sliding in a chamber (24) formed by a portion of the container, a load tank (33) formed by a remaining portion of said container and designed to contain the substance to be delivered, a metering mechanism (12) associated and moving with the piston (25), a preloaded thrusting device (27) associated with the piston with the metering mechanism to push it normally towards the substance in the load tank, and blocking means (12) between the metering mechanism and the container to alternately stop and release the piston to have it move forward under the thrust of said preloaded flexible device in lengths corresponding to a dose of the substance.
    Type: Application
    Filed: October 30, 2006
    Publication date: November 20, 2008
    Inventor: Gianfranco de Paoli Ambrosi
  • Patent number: 7169811
    Abstract: The present invention relates to a composition for topical use for treating and improving the aesthetic conditions of the skin, which comprises, as an active ingredient, a mixture of ethyllinoleate and triethylcitrate. This composition is active in the treatment of seborrhea and acne.
    Type: Grant
    Filed: December 16, 2002
    Date of Patent: January 30, 2007
    Assignee: General Topics S.r.l.
    Inventor: Gianfranco de Paoli Ambrosi
  • Publication number: 20070010580
    Abstract: The present invention refers to a new formulation able to increase the efficacy and the tolerability of preparations based on the use of compounds used to carry out chemical peeling. More particularly, the present invention refers to a composition for chemical peeling, comprising at least one keratolytic agent and dimethyl isosorbide. The composition may additionally comprise dimethyl sulphone.
    Type: Application
    Filed: May 30, 2003
    Publication date: January 11, 2007
    Inventor: Gianfranco De Paoli Ambrosi
  • Publication number: 20070009451
    Abstract: The present invention has as subject a new composition for cosmetic or pharmaceutical use intended for external use to be applied both to undamaged and damaged skin or onto the mucosa to reduce or inhibit irritation, inflammation and cutaneous erythemia induced by events of an exogenous nature (irritations induced by chemical agents, pharmaceuticals, cosmetic ingredients, physical agents—such as, for example, solar radiation, ultraviolet radiation, ionising radiation, X rays, gamma rays, laser light—bacterial agents, viral agents, etc) and to photoprotect the skin from solar radiation and specifically from damage induced by ultraviolet radiation of types A, B and C. More particularly, the present invention refers to the use of dimethyl sulphone in the preparation of a pharmaceutical or cosmetic composition for topical use, to prevent and/or cure the above mentioned cutaneous manifestations.
    Type: Application
    Filed: May 30, 2003
    Publication date: January 11, 2007
    Inventor: Gianfranco de Paoli Ambrosi
  • Publication number: 20060063835
    Abstract: This invention concerns a composition for topical use containing as an active ingredient triethyl citrate either pure or in combination with synergists, and the pharmaceutical or cosmetic use of the composition, on its own or in association with an antibiotic, at least in the treatment of cutaneous pathologies directly or indirectly affected by bacterial infections.
    Type: Application
    Filed: September 2, 2003
    Publication date: March 23, 2006
    Inventor: Gianfranco De Paoli Ambrosi
  • Publication number: 20030118623
    Abstract: The present invention relates to a composition for topical use for treating and improving the aesthetic conditions of the skin, which comprises, as an active ingredient, a mixture of ethyllinoleate and triethylcitrate. This composition is active in the treatment of seborrhea and acne.
    Type: Application
    Filed: December 16, 2002
    Publication date: June 26, 2003
    Inventor: Gianfranco de Paoli Ambrosi
  • Patent number: 6147054
    Abstract: A composition for cosmetic, pharmaceutical or dietetic use and including as the active ingredient, at least one of the substances which include acetylglucosamine and glucuronic acid in combination with the active ingredients which belong to the chemical class of the carboxylic acids, .alpha.-hydroxy acids, vitamins, amino acids, and bioflavonoids, and formulated with particular synergists, additives, and excipients for external use or for internal use.
    Type: Grant
    Filed: November 17, 1997
    Date of Patent: November 14, 2000
    Inventor: Gianfranco De Paoli Ambrosi