Abstract: A pharmaceutical composition for the prevention and treatment of human cognitive deficit includes oleuropein or its derivatives and glutathione conjugated with a carboxylic acid. The carboxylic acid component of the glutathione-carboxylic acid conjugate is any saturated or unsaturated aliphatic carboxylic acid, containing from 2 to 22 carbon atoms.

Abstract: In a method and device for high sensitivity analysis of multiple bioassays plurality of nanoparticles (N) is dispersed in a fluid sample, at least one probe (C) of a first type having affinity for at least one analyte being attached to each nanoparticle; a plurality of probes of at least a second type having affinity for the analyte is attached to the internal surface (S) of the container; means are provided for detecting the signal generated by the adhesion of the nanoparticles to the internal surface of the reactor, brought about by the interaction of the analyte with the nanoparticle-bound probes and that of the analyte with the probes attached to the internal surface. The method and the device are particularly effective for detecting different genotypes of human papilloma virus (HPV).