Patents by Inventor Gianfranco Marca

Gianfranco Marca has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Derivatives of the D-threo-1-phenyl-2-trifluoroacetamido-1,3-propandediol
    Patent number: 4188402
    Abstract: A novel class of D-Threo-1-phenyl-1-trifluoroacetamido-1, 3-propanediols wherein the benzene ring is substituted in the para-position by methylmercapto or methanesulphonyl and the hydroxy moiety at position 3 of the prepanediol is acylated to afford alkanoyloxy, halo-alkanoyloxy or aminoalkanoyloxy.The instant products are prepared: (1) by treating a D-threo-1-(p-methanesulphonylphenyl)-2-amino-1,3-propanediol or a D-threo-1-(p-methylmercaptophenyl)-2-amino-1,3-propanediol with trifluoroacetic acid or with an ester derivative thereof; (2) by oxidation of the mercapto moiety in a D-threo-1-(p-methylmercaptophenyl)-2-trifluoroacetamido-1, 3-propanediol to afford the corresponding 1-(p-methanesulphonyl) derivative; or (3) by esterification of the 3-hydroxy moiety in a D-threo-1-phenyl-2-trifluoroacetamido-1, 3-propanediol precursor.
    Type: Grant
    Filed: August 5, 1977
    Date of Patent: February 12, 1980
    Assignee: Clesa S.p.A.
    Inventors: Mario Portelli, Davide DellaBella, Giuseppe Cervato, Gianfranco Marca