Patents by Inventor Gianluca Bianchini

Gianluca Bianchini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synergistic admixtures of Gabapentin and Ketoprofen, pharmaceutical compositions and their medical use
    Patent number: 12667549
    Abstract: The present invention relates to a synergistic admixture of Gabapentin and Ketoprofen, preferably Ketoprofen Lysine, to a pharmaceutical composition comprising said admixtures and to the use of said admixtures or pharmaceutical compositions in the treatment of acute or chronic pain, in particular in the treatment of neuropathic or inflammatory pain.
    Type: Grant
    Filed: April 21, 2021
    Date of Patent: June 30, 2026
    Assignee: DOMPÉ FARMACEUTICI S.P.A.
    Inventors: Andrea Aramini, Marcello Allegretti, Gianluca Bianchini, Samuele Lillini, Mara Tomassetti, Laura Brandolini
  • COMPOSITION FOR THE TREATMENT OF MUSCLE WASTING
    Publication number: 20260102367
    Abstract: The present invention relates to compositions comprising branched-chain amino acids (BCAA) and the amino acid L-Alanine and their use in the prevention and/or treatment of muscle wasting associated to pathological or age-related conditions.
    Type: Application
    Filed: December 17, 2025
    Publication date: April 16, 2026
    Inventors: Marcello ALLEGRETTI, Andrea ARAMINI, Gianluca BIANCHINI
  • Co-crystal of gabapentin, ketoprofen and lysine, pharmaceutical compositions and their medical use
    Patent number: 12582624
    Abstract: The present invention relates to a new co-crystal of Gabapentin, Ketoprofen and Lysine, to pharmaceutical compositions and to their use in the prevention, reduction or treatment of pain and/or inflammation.
    Type: Grant
    Filed: April 21, 2021
    Date of Patent: March 24, 2026
    Assignee: DOMPÉ FARMACEUTICI S.P.A.
    Inventors: Andrea Aramini, Marcello Allegretti, Gianluca Bianchini, Samuele Lillini, Mara Tomassetti
  • STABLE MONOHYDRATE OF DF2755A AND PROCESS FOR ITS PREPARATION
    Publication number: 20260076949
    Abstract: The present invention relates to a stable monohydrate of compound DF2755A, to a process for its manufacture, to its pharmaceutical compositions and medical uses. The monohydrate of compound DF2755A of the present invention is physically, chemically and optically stable, thus particularly advantageous for pharmaceutical applications.
    Type: Application
    Filed: August 1, 2025
    Publication date: March 19, 2026
    Inventors: Gianluca BIANCHINI, Andrea ARAMINI, Marcello ALLEGRETTI
  • COMBINATION FOR USE IN OPHTHALMOLOGY
    Publication number: 20260041733
    Abstract: The present invention relates to a combination of nerve growth factor and sesamin, and uses thereof in the treatment of ophthalmic disorders.
    Type: Application
    Filed: July 27, 2023
    Publication date: February 12, 2026
    Inventors: Tiziana ROMEO, Nicola DETTA, Flavio MANTELLI, Mara TOMASSETTI, Gianluca BIANCHINI, Samuele LILLINI, Andrea ARAMINI, Laura BRANDOLINI, Pasquale COCCHIARO
  • Co-crystal of ketoprofen and its preparation, pharmaceutical compositions comprising the same and uses thereof
    Patent number: 12528760
    Abstract: The present invention refers to a co-crystal of Ketoprofen Lysine named Form 4, a pharmaceutical composition comprising said co-crystal, a process for its preparation and to its use in the treatment of pain and inflammatory diseases.
    Type: Grant
    Filed: December 21, 2020
    Date of Patent: January 20, 2026
    Assignee: DOMPÉ FARMACEUTICI S.P.A.
    Inventors: Andrea Aramini, Gianluca Bianchini, Samuele Lillini
  • Composition for the treatment of muscle wasting
    Patent number: 12521359
    Abstract: The present invention relates to compositions comprising branched-chain amino acids (BCAA) and the amino acid L-Alanine and their use in the prevention and/or treatment of muscle wasting associated to pathological or age-related conditions.
    Type: Grant
    Filed: June 29, 2020
    Date of Patent: January 13, 2026
    Assignee: DOMPÉ FARMACEUTICI S.P.A.
    Inventors: Marcello Allegretti, Andrea Aramini, Gianluca Bianchini
  • CO-CRYSTAL OF KETOPROFEN, COMPOSITIONS COMPRISING THE SAME, PROCESS OF PRODUCING THE SAME, AND USES THEREOF
    Publication number: 20250312301
    Abstract: The present invention refers to a co-crystal of Ketoprofen Lysine named Form 1, a pharmaceutical composition comprising said co-crystal, a process for its production and to its use in the treatment of pain and inflammatory diseases.
    Type: Application
    Filed: March 14, 2025
    Publication date: October 9, 2025
    Inventors: Andrea ARAMINI, Gianluca BIANCHINI, Samuele LILLINI
  • Co-crystal of ketoprofen, lysine and gabapentin, pharmaceutical compositions and their medical use
    Patent number: 12365644
    Abstract: The present invention relates to a new co-crystal of Ketoprofen, Lysine and Gabapentin, to pharmaceutical compositions and to their use in the prevention, reduction or treatment of pain and/or inflammation.
    Type: Grant
    Filed: May 4, 2021
    Date of Patent: July 22, 2025
    Assignee: DOMPÈ FARMACEUTICI S.P.A.
    Inventors: Andrea Aramini, Marcello Allegretti, Gianluca Bianchini, Samuele Lillini, Mara Tomassetti
  • GPR120 AGONISTS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE
    Publication number: 20250177329
    Abstract: The present invention relates to GPR120 agonists for use in the treatment of inflammatory bowel disease, in particular ulcerative colitis or Crohn's disease.
    Type: Application
    Filed: March 3, 2023
    Publication date: June 5, 2025
    Inventors: Marcello ALLEGRETTI, Andrea ARAMINI, Gianluca BIANCHINI, Silvia D'ALESSIO, Rafael CYPRIANO DUTRA
  • Co-crystal of ketoprofen, compositions comprising the same, process of producing the same, and uses thereof
    Patent number: 12285396
    Abstract: The present invention relates to a co-crystal of Ketoprofen Lysine named Form 1, characterized by its X-ray powder diffraction diagram, a pharmaceutical composition comprising the co-crystal of Ketoprofen Lysine, a process for the production of the co-crystal of Ketoprofen Lysine, and the use of the co-crystal of Ketoprofen Lysine in the treatment of pain and inflammatory diseases.
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: April 29, 2025
    Assignee: DOMPÉ FARMACEUTICI S.P.A.
    Inventors: Andrea Aramini, Gianluca Bianchini, Samuele Lillini
  • IL-8 INIHIBITORS FOR USE IN THE TREATMENT OF SOME UROLOGICAL DISORDERS
    Publication number: 20250032461
    Abstract: The present invention relates to IL-8 inhibitor compounds, preferably dual CXCR1/CXCR2 receptor inhibitors, useful in the treatment and/or prevention of interstitial cystitis/painful bladder syndrome (IC/PBS) and/or over active bladder (OAB), also including IC/PBS and/or OAB induced by anticancer therapy. Methods of treatment and/or prevention, combinations and kits comprising said IL-8 inhibitors are also covered therein.
    Type: Application
    Filed: October 17, 2024
    Publication date: January 30, 2025
    Inventors: Marcello ALLEGRETTI, Andrea ARAMINI, Maria Candida CESTA, Gianluca BIANCHINI, Laura BRANDOLINI, Patrizia ANGELICO
  • CO-CRYSTALS OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS, LYSINE AND GABAPENTIN, PHARMACEUTICAL COMPOSITIONS AND THEIR MEDICAL USE
    Publication number: 20250025435
    Abstract: The present invention relates to new co-crystals of non-steroidal anti-inflammatory drugs (NSAIDs) belonging to the class of phenylpropionic or phenylacetic acid derivatives. Lysine and Gabapentin, to their pharmaceutical compositions and to their use in the prevention, reduction or treatment of pain and/or inflammation.
    Type: Application
    Filed: October 25, 2022
    Publication date: January 23, 2025
    Inventors: Andrea ARAMINI, Gianluca BIANCHINI, Samuele LILLINI, Mara TOMASSETTI, Laura BRANDOLINI
  • Composition containing branched-chain amino acids
    Patent number: 12186359
    Abstract: The present invention relates to compositions comprising branched-chain amino acids (BCAA) and the dipeptide L-Alanyl-L-alanine and their use for improving the performance and recovery during physical activity and for the prevention and/or treatment of muscle wasting associated to pathological or age-related conditions.
    Type: Grant
    Filed: June 29, 2020
    Date of Patent: January 7, 2025
    Assignee: DOMPÉ FARMACEUTICI S.P.A.
    Inventors: Marcello Allegretti, Andrea Aramini, Gianluca Bianchini
  • C5AR INHIBITORS FOR USE IN THE TREATMENT OF CHEMOTHERAPY-INDUCED IATROGENIC PAIN
    Publication number: 20240398731
    Abstract: The present invention relates to C5aR inhibitor compounds, preferably C5aR noncompetitive allosteric inhibitors, useful in the treatment and/or prevention of chemotherapy-induced iatrogenic pain (CIIP).
    Type: Application
    Filed: August 9, 2024
    Publication date: December 5, 2024
    Inventors: Laura BRANDOLINI, Thiago Mattar CUNHA, Marcello ALLEGRETTI, Andrea ARAMINI, Gianluca BIANCHINI
  • IL-8 inihibitors for use in the treatment of some urological disorders
    Patent number: 12150933
    Abstract: The present invention relates to IL-8 inhibitor compounds, preferably dual CXCR1/CXCR2 receptor inhibitors, useful in the treatment and/or prevention of interstitial cystitis/painful bladder syndrome (IC/PBS) and/or over active bladder (OAB), also including IC/PBS and/or OAB induced by anticancer therapy. Methods of treatment and/or prevention, combinations and kits comprising said IL-8 inhibitors are also covered therein.
    Type: Grant
    Filed: July 12, 2016
    Date of Patent: November 26, 2024
    Assignee: DOMPÈ FARMACEUTICI S.P.A.
    Inventors: Marcello Allegretti, Andrea Aramini, Maria Candida Cesta, Gianluca Bianchini, Laura Brandolini, Patrizia Angelico
  • C5aR inhibitors for use in the treatment of chemotherapy-induced iatrogenic pain
    Patent number: 12102607
    Abstract: The present invention relates to C5aR inhibitor compounds, preferably C5aR noncompetitive allosteric inhibitors, useful in the treatment and/or prevention of chemotherapy-induced iatrogenic pain (CIIP).
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: October 1, 2024
    Assignee: Dompe' Farmaceutici S.P.A.
    Inventors: Laura Brandolini, Thiago Mattar Cunha, Marcello Allegretti, Andrea Aramini, Gianluca Bianchini
  • CO-CRYSTAL OF KETOPROFEN, LYSINE AND GABAPENTIN, PHARMACEUTICAL COMPOSITIONS AND THEIR MEDICAL USE
    Publication number: 20230357121
    Abstract: The present invention relates to a new co-crystal of Ketoprofen, Lysine and Gabapentin, to pharmaceutical compositions and to their use in the prevention, reduction or treatment of pain and/or inflammation.
    Type: Application
    Filed: May 4, 2021
    Publication date: November 9, 2023
    Inventors: Andrea ARAMINI, Marcello ALLEGRETTI, Gianluca BIANCHINI, Samuele LILLINI, Mara TOMASSETTI
  • CO-CRYSTAL OF GABAPENTIN, KETOPROFEN AND LYSINE, PHARMACEUTICAL COMPOSITIONS AND THEIR MEDICAL USE
    Publication number: 20230181507
    Abstract: The present invention relates to a new co-crystal of Gabapentin, Ketoprofen and Lysine, to pharmaceutical compositions and to their use in the prevention, reduction or treatment of pain and/or inflammation.
    Type: Application
    Filed: April 21, 2021
    Publication date: June 15, 2023
    Inventors: Andrea ARAMINI, Marcello ALLEGRETTI, Gianluca BIANCHINI, Samuele LILLINI, Mara TOMASSETTI
  • SYNERGISTIC ADMIXTURES OF GABAPENTIN AND KETOPROFEN, PHARMACEUTICAL COMPOSITIONS AND THEIR MEDICAL USE
    Publication number: 20230165820
    Abstract: The present invention relates to a synergistic admixture of Gabapentin and Ketoprofen, preferably Ketoprofen Lysine, to a pharmaceutical composition comprising said admixtures and to the use of said admixtures or pharmaceutical compositions in the treatment of acute or chronic pain, in particular in the treatment of neuropathic or inflammatory pain.
    Type: Application
    Filed: April 21, 2021
    Publication date: June 1, 2023
    Inventors: Andrea ARAMINI, Marcello ALLEGRETTI, Gianluca BIANCHINI, Samuele LILLINI, Mara TOMASSETTI, Laura BRANDOLINI