Patents by Inventor Gianluca PIROZZI

Gianluca PIROZZI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATING CHRONIC SINUSITIS WITH NASAL POLYPS BY ADMINISTERING AN IL-4R ANTAGONIST
    Publication number: 20220204631
    Abstract: The present invention provides methods for decreasing a nasal polyp score in a subject. The methods include administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody or antigen binding fragment thereof.
    Type: Application
    Filed: November 23, 2021
    Publication date: June 30, 2022
    Inventors: Leda Mannent, Gianluca Pirozzi, Brian Swanson, Allen Radin, Namita A. Gandhi, Robert Evans, Jennifer Hamilton
  • METHODS FOR TREATING SEVERE ATOPIC DERMATITIS BY ADMINISTERING AN IL-4R INHIBITOR
    Publication number: 20220110999
    Abstract: The present invention provides methods for treating moderate-to-severe or severe atopic dermatitis (AD). The methods of the present invention comprise administering to a subject in need thereof one or more doses of an interleukin-4 receptor (IL-4R) inhibitor such as an anti-IL-4R antibody. In certain embodiments, the methods of the present invention are used to treat severe AD in a patient whose disease is not controlled with systemic therapy (e.g., cyclosporine A) or when such therapy is inadvisable.
    Type: Application
    Filed: September 22, 2021
    Publication date: April 14, 2022
    Inventors: Allen RADIN, Neil GRAHAM, Bolanle AKINLADE, Gianluca PIROZZI, Xing SUN, Thomas HULTSCH, Brad S. SHUMEL, Ashish BANSAL
  • Methods for treating chronic sinusitis with nasal polyps by administering an IL-4R antagonist
    Patent number: 11214621
    Abstract: The present invention provides methods for decreasing a nasal polyp score in a subject. The methods include administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody or antigen binding fragment thereof.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: January 4, 2022
    Assignees: SANOFI BIOTECHNOLOGY, REGENERON PHARMACEUTICALS, INC.
    Inventors: Leda Mannent, Gianluca Pirozzi, Brian Swanson, Allen Radin, Namita A. Gandhi, Robert Evans, Jennifer Hamilton
  • METHODS FOR TREATING OR PREVENTING ASTHMA BY ADMINISTERING AN IL-4R ANTAGONIST
    Publication number: 20210380705
    Abstract: The invention provides methods for treating or preventing asthma and associated conditions in a patient. The methods featured in the invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody.
    Type: Application
    Filed: May 7, 2021
    Publication date: December 9, 2021
    Inventors: Nikhil Amin, Neil Graham, Gianluca Pirozzi, Ariel Teper
  • Methods for treating severe atopic dermatitis by administering an IL-4R inhibitor
    Patent number: 11167004
    Abstract: The present invention provides methods for treating moderate-to-severe or severe atopic dermatitis (AD). The methods of the present invention comprise administering to a subject in need thereof one or more doses of an interleukin-4 receptor (IL-4R) inhibitor such as an anti-IL-4R antibody. In certain embodiments, the methods of the present invention are used to treat severe AD in a patient whose disease is not controlled with systemic therapy (e.g., cyclosporine A) or when such therapy is inadvisable.
    Type: Grant
    Filed: July 16, 2019
    Date of Patent: November 9, 2021
    Assignees: Regeneron Pharmaceuticals, Inc., Sanofi Biotechnology
    Inventors: Allen Radin, Neil Graham, Bolanle Akinlade, Gianluca Pirozzi, Xing Sun, Thomas Hultsch, Brad S. Shumel, Ashish Bansal
  • METHODS FOR TREATING OR PREVENTING ASTHMA BY ADMINISTERING AN IL-4R ANTAGONIST
    Publication number: 20210322546
    Abstract: The invention provides methods for treating or preventing asthma and associated conditions in a patient. The methods featured in the invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody.
    Type: Application
    Filed: March 29, 2021
    Publication date: October 21, 2021
    Inventors: Gianluca Pirozzi, Franck Skobieranda, Yongtao Li, Neil Graham, Steven P. Weinstein
  • Methods for treating or preventing asthma by administering an IL-4R antagonist
    Patent number: 11034768
    Abstract: The invention provides methods for treating or preventing asthma and associated conditions in a patient. The methods featured in the invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody.
    Type: Grant
    Filed: October 29, 2018
    Date of Patent: June 15, 2021
    Assignees: REGENERON PHARMACEUTICALS, INC.
    Inventors: Nikhil Amin, Neil Graham, Gianluca Pirozzi, Ariel Teper
  • METHODS FOR TREATING SEVERE ATOPIC DERMATITIS BY ADMINISTERING AN IL-4R INHIBITOR
    Publication number: 20200246416
    Abstract: The present invention provides methods for treating moderate-to-severe or severe atopic dermatitis (AD). The methods of the present invention comprise administering to a subject in need thereof one or more doses of an interleukin-4 receptor (IL-4R) inhibitor such as an anti-IL-4R antibody. In certain embodiments, the methods of the present invention are used to treat severe AD in a patient whose disease is not controlled with systemic therapy (e.g., cyclosporine A) or when such therapy is inadvisable.
    Type: Application
    Filed: July 16, 2019
    Publication date: August 6, 2020
    Inventors: ALLEN Radin, NEIL GRAHAM, BOLANLE AKINLADE, GIANLUCA PIROZZI, XING SUN, THOMAS HULTSCH, BRAD S. SHUMEL, ASHISH BANSAL
  • Methods for treating severe atopic dermatitis by administering an IL-4R inhibitor
    Patent number: 10485844
    Abstract: The present invention provides methods for treating moderate-to-severe or severe atopic dermatitis (AD). The methods of the present invention comprise administering to a subject in need thereof one or more doses of an interleukin-4 receptor (IL-4R) inhibitor such as an anti-IL-4R antibody. In certain embodiments, the methods of the present invention are used to treat severe AD in a patient whose disease is not controlled with systemic therapy (e.g., cyclosporine A) or when such therapy is inadvisable.
    Type: Grant
    Filed: September 21, 2017
    Date of Patent: November 26, 2019
    Assignees: Regeneron Pharmaceuticals, Inc., Sanofi Biotechnology
    Inventors: Allen Radin, Neil Graham, Bolanle Akinlade, Gianluca Pirozzi, Xing Sun, Thomas Hultsch, Brad S. Shumel, Ashish Bansal
  • METHODS FOR TREATING OR PREVENTING ASTHMA BY ADMINISTERING AN IL-4R ANTAGONIST
    Publication number: 20190169299
    Abstract: The invention provides methods for treating or preventing asthma and associated conditions in a patient. The methods featured in the invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody.
    Type: Application
    Filed: October 29, 2018
    Publication date: June 6, 2019
    Inventors: Nikhil Amin, Neil Graham, Gianluca Pirozzi, Ariel Teper
  • METHODS FOR TREATING OR PREVENTING ASTHMA BY ADMINISTERING AN IL-4R ANTAGONIST
    Publication number: 20190125865
    Abstract: The invention provides methods for treating or preventing asthma and associated conditions in a patient. The methods featured in the invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody.
    Type: Application
    Filed: October 11, 2018
    Publication date: May 2, 2019
    Inventors: Gianluca Pirozzi, Franck Skobieranda, Yongtao Li, Neil Graham, Steven P. Weinstein
  • METHODS FOR TREATING CHRONIC SINUSITIS WITH NASAL POLYPS BY ADMINISTERING AN IL-4R ANTAGONIST
    Publication number: 20190040147
    Abstract: The present invention provides methods for decreasing a nasal polyp score in a subject. The methods include administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody or antigen binding fragment thereof.
    Type: Application
    Filed: July 18, 2018
    Publication date: February 7, 2019
    Inventors: Leda Mannent, Gianluca Pirozzi, Brian Swanson, Allen Radin, Namita A. Gandhi, Robert Evans, Jennifer Hamilton
  • METHODS FOR TREATING NASAL POLYPOSIS BY ADMINISTERING AN IL-4R ANTAGONIST
    Publication number: 20190040146
    Abstract: The present invention provides methods for treating nasal polyposis. The methods include administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody or antigen binding fragment thereof.
    Type: Application
    Filed: July 18, 2018
    Publication date: February 7, 2019
    Inventors: Leda Mannent, Gianluca Pirozzi, Allen Radin, Namita A. Gandhi, Robert Evans
  • Methods for treating or preventing asthma by administering an IL-4R antagonist
    Patent number: 10137193
    Abstract: The invention provides methods for treating or preventing asthma and associated conditions in a patient. The methods featured in the invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody.
    Type: Grant
    Filed: February 20, 2015
    Date of Patent: November 27, 2018
    Assignees: Sanofi Biotechnology, Regeneron Pharmaceuticals, Inc.
    Inventors: Gianluca Pirozzi, Franck Skobieranda, Yongtao Li, Neil Graham, Steven P. Weinstein
  • Methods for treating chronic sinusitis with nasal polyps by administering an IL-4R antagonist
    Patent number: 10066017
    Abstract: The present invention provides methods for decreasing a nasal polyp score in a subject. The methods include administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody or antigen binding fragment thereof.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: September 4, 2018
    Assignees: SANOFI BIOTECHNOLOGY, REGENERON PHARMACEUTICALS, INC
    Inventors: Leda Mannent, Gianluca Pirozzi, Brian Swanson, Allen Radin, Namita A. Gandhi, Robert Evans, Jennifer Hamilton
  • Methods for treating nasal polyposis by administering an IL-4R antagonist
    Patent number: 10059771
    Abstract: The present invention provides methods for treating nasal polyposis. The methods include administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody or antigen binding fragment thereof.
    Type: Grant
    Filed: June 20, 2014
    Date of Patent: August 28, 2018
    Assignees: SANOFI BIOTECHNOLOGY, REGENERON PHARMACEUTICALS, INC.
    Inventors: Leda Mannent, Gianluca Pirozzi, Allen Radin, Namita A. Gandhi, Robert Evans
  • Methods for Treating Severe Atopic Dermatitis by Administering an IL-4R Inhibitor
    Publication number: 20180078603
    Abstract: The present invention provides methods for treating moderate-to-severe or severe atopic dermatitis (AD). The methods of the present invention comprise administering to a subject in need thereof one or more doses of an interleukin-4 receptor (IL-4R) inhibitor such as an anti-IL-4R antibody. In certain embodiments, the methods of the present invention are used to treat severe AD in a patient whose disease is not controlled with systemic therapy (e.g., cyclosporine A) or when such therapy is inadvisable.
    Type: Application
    Filed: September 21, 2017
    Publication date: March 22, 2018
    Inventors: Allen RADIN, Neil GRAHAM, Bolanle AKINLADE, Gianluca PIROZZI, Xing SUN, Thomas HULTSCH, Brad S. SHUMEL, Ashish BANSAL
  • METHODS FOR TREATING CHRONIC SINUSITIS WITH NASAL POLYPS BY ADMINISTERING AN IL-4R ANTAGONIST
    Publication number: 20160185866
    Abstract: The present invention provides methods for decreasing a nasal polyp score in a subject. The methods include administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody or antigen binding fragment thereof.
    Type: Application
    Filed: November 13, 2015
    Publication date: June 30, 2016
    Inventors: Leda Mannent, Gianluca Pirozzi, Brian Swanson, Allen Radin, Namita A. Gandhi, Robert Evans, Jennifer Hamilton
  • METHODS FOR TREATING OR PREVENTING ASTHMA BY ADMINISTERING AN IL-4R ANTAGONIST
    Publication number: 20150246119
    Abstract: The invention provides methods for treating or preventing asthma and associated conditions in a patient. The methods featured in the invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody.
    Type: Application
    Filed: February 20, 2015
    Publication date: September 3, 2015
    Inventors: Gianluca Pirozzi, Franck Skobieranda, Yongtao Li, Neil Graham, Steven P. Weinstein
  • METHODS FOR TREATING NASAL POLYPOSIS BY ADMINISTERING AN IL-4R ANTAGONIST
    Publication number: 20150017182
    Abstract: The present invention provides methods for treating nasal polyposis. The methods include administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody or antigen binding fragment thereof.
    Type: Application
    Filed: June 20, 2014
    Publication date: January 15, 2015
    Inventors: Leda MANNENT, Gianluca PIROZZI, Allen RADIN, Namita A. GANDHI, Robert EVANS