Patents by Inventor Gianni Gromo

Gianni Gromo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6130210
    Abstract: Heparin derivatives are disclosed that may be used to inhibit formation of metastases. One series of heparin derivatives of the invention are N-acylated with monocarboxylic acids or dicarboxylic acids and have molecular weights from about 1000 Daltons to about 30,000 Daltons. Another series of heparin derivatives of the invention have average molecular weights ranging from about 1000 to 3000 daltons, and are optionally N-acylated with residues from aliphatic monocarboxylic or dicarboxylic acids.
    Type: Grant
    Filed: March 31, 1998
    Date of Patent: October 10, 2000
    Assignee: Italfarmaco S.p.A.
    Inventors: Patrizia Caretto, Teresa Sciumbata, Flavio Leoni, Gianni Gromo
  • Patent number: 6057295
    Abstract: Oligopeptides derived from fragments of C-reactive proteins and their use as immunomodulating agents in the therapy of cardiovascular and inflammatory diseases.
    Type: Grant
    Filed: June 11, 1996
    Date of Patent: May 2, 2000
    Assignee: Italfarmaco S.p.A.
    Inventors: Patrizia Caretto, Flavio Leoni, Fabrizio Marcucci, Gianni Gromo, Paolo Mascagni, Massimo Pinori, Silvana Cappelletti
  • Patent number: 5856305
    Abstract: Peptides endowed with antiinflammatory activity consisting of 25 aminoacids having a sequence with an homology of at least 25% with the 1-25 fragment of the 10 Kda heat shock protein from Mycobacterium tuberculosis.
    Type: Grant
    Filed: July 17, 1997
    Date of Patent: January 5, 1999
    Assignee: Italfarmaco S.P.A.
    Inventors: Pierluigi Lucietto, Paola Giuliani, Gianluca Fossati, Paolo Mascagni, Gianni Gromo
  • Patent number: 5827881
    Abstract: Diesters of carbonic acid disubstituted with primary, secondary or tertiary amine groups, pharmaceutically acceptable salts thereof, and their use as antiviral and inti-inflammatory agents.
    Type: Grant
    Filed: June 4, 1997
    Date of Patent: October 27, 1998
    Assignee: Italfarmaco S.P.A.
    Inventors: Alberto Sala, Giorgio Bertolini, Gianfranco Pavich, Fabrizio Marcucci, Gianni Gromo, Giuliana Porro
  • Patent number: 5763421
    Abstract: Heparin derivatives are disclosed which may be used to inhibit formation of metastases. The heparin derivatives of the invention are N-acylated with mono- or dicarboxylic acids, have a molecular weight from about 1,000 to about 30,000 Daltons, and have at least one unit of an open D- or L-iduronic acid.
    Type: Grant
    Filed: March 5, 1996
    Date of Patent: June 9, 1998
    Assignee: Italfarmaco S.p.A.
    Inventors: Patrizia Caretto, Teresa Sciumbata, Flavio Leoni, Gianni Gromo
  • Patent number: 5501970
    Abstract: This invention refers to DNA sequences coding for proteins present in the plant Dianthus caryophyllus, to expression vectors containing said sequences and to hosts transformed by said vectors.
    Type: Grant
    Filed: May 13, 1994
    Date of Patent: March 26, 1996
    Assignee: ITALFARMACO S.p.A.
    Inventors: Giuseppe Legname, Gianni Gromo, Daniela Modena, Diego Brocchetti
  • Patent number: 5480882
    Abstract: Compounds of formula I ##STR1## wherein R represents hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.5 -C.sub.7 cycloalkyl, methylene-dioxy or phenyl, which may be substituted by one or two groups independently selected from hydroxy, halogen, nitro, C.sub.1 -C.sub.6 alkyl or C.sub.1 -C.sub.6 alkoxy; R.sub.1 and R.sub.2 independently represent hydrogen, COOR.sub.3, --CONR.sub.4 R.sub.5, ##STR2## --OCONR.sub.4 R.sub.5, --OCOR.sub.3, --NR.sub.4 R.sub.5, --OCOOR.sub.6, --NR.sub.3 COR.sub.7, --NR.sub.CONR.sub.4 R.sub.5, --N.dbd.CH--NR.sub.4 R.sub.5, NO.sub.2, CN, OH, SR.sub.3, wherein R.sub.3 is hydrogen or C.sub.1 -C.sub.6 alkyl, R.sub.4 and R.sub.5 independently are hydrogen or C.sub.1 -C.sub.6 alkyl, R.sub.6 is C.sub.1 -C.sub.6 alkyl, and R.sub.7 is hydrogen, C.sub.1 -C.sub.6 alkyl or C.sub.1 -C.sub.6 alkoxy, with the proviso that R.sub.1 and R.sub.2 cannot be hydrogen at the same time; X is oxygen or sulphur; Y represents a C.sub.2 -C.sub.6 alkylene chain or a C.sub.5 -C.sub.
    Type: Grant
    Filed: November 23, 1994
    Date of Patent: January 2, 1996
    Assignee: Italfarmaco S.p.A.
    Inventors: Alberto Sala, Roberto Barani, Francesca Benedini, Giorgio Bertolini, Giancarlo Dona, Gianni Gromo, Silvio Levi