Abstract: A cap for medical fluid lines and the like includes a hollow body within which a male or female connector accessible at one end of the body is coaxially housed. The connector is configured to inviolably obstruct the passage through the body. A unidirectional coupling locks in rotation the connector with respect to the body in the direction corresponding to the screwing of the connector, and a complementary connector, and to enable free rotation of the connector in the opposite direction. The connector can be possibly locked in rotation with respect to the body in the unscrewing direction, only following a positive command.

Abstract: A tubular fitting for medical fluid lines includes a hollow body within which a male connector and an opposite female connector are coaxially housed. The male connector is coupled in rotation with respect to the body in a direction corresponding to a screwing with a female connector of the line, while it is normally freely rotatable in the unscrewing direction, in the same way as the female connector is coupled in rotation with respect to the body in the direction corresponding to the screwing with a male connector of the line, while it is normally freely rotatable in the unscrewing direction. The male connector and/or the female connector can possibly be locked in rotation with respect to the body in the unscrewing direction, only following a positive command.

Abstract: An access device for containers of fluidizable substances includes a body provided with a hollow spike designed to be inserted into a container of a substance to fluidize and having an axial fluid passage and an axial passage for venting of the container, an expandable chamber connected to the venting passage of the spike through a lateral passage of the body, a first check valve enabling one-way communication from the lateral passage to the expandable chamber, a second check valve enabling one-way communication from a vent opening to the venting passage of the spike. A double impermeable filtering membrane is interposed between the first check valve and the second check valve.

Abstract: A valved male luer connector includes a resilient hollow element enclosing a tubular member having an inlet portion and an outlet portion. A collar is axially displaceable to cause a stretching deformation of the resilient hollow element so as to open a cut of a terminal wall thereof adjacent to an initial end of the inlet portion of the tubular member. The collar has a containment axial appendage of the resilient hollow element up to close to the terminal wall thereof. A stop means for limiting the stretching deformation of the resilient hollow element is provided for in the zone close to the terminal wall thereof.

Abstract: A vial access device is described comprising an upper housing having a fluid connecter in fluid communication with the upper housing; a vial access spike projecting from the upper housing; a fluid filter body within the upper housing or connectable thereto, the fluid filter body in fluid communication with the vial access spike and the fluid connector. Methods of reducing or eliminating particulate matter from medicament solutions are also provided.

Abstract: A flow system for medical lines includes a flow component having a main duct and at least one lateral tubular fitting with a female luer cone communicating with the main duct) through a valve. The valve includes a transverse diaphragm normally kept in fluid-tight contact against an annular valve seat of the lateral tubular fitting, which can be moved away from this into an opening position following upon insertion of a male luer-cone introducer of fluid into the lateral tubular fitting. The diaphragm is prearranged for being pushed into the opening position directly by the introducer, and the lateral tubular fitting is configured to couple in a fluid-tight way with the introducer before the latter comes into contact of thrust with the diaphragm.

Abstract: A valved male luer connector includes an elastic hollow element which encloses a tubular member having an inlet portion and an outlet portion. A collar is axially displaceable causing a stretching deformation of the elastic hollow element and opening the flow passage between the inlet portion and the outlet portion of the tubular member. A priming cap is designed to be releasably connected to the casing of the valved connector to provide stretching deformation of the elastic element and keep the outlet portion of the tubular member in communication with the atmosphere through a liquid-impermeable barrier.

Abstract: A valved male luer connector includes an elastic hollow element enclosing a tubular member having an inlet portion and an outlet portion. A collar is axially displaceable to cause a stretching deformation of the elastic hollow element and open a flow passage between the inlet portion and the outlet portion of the tubular member. The inlet portion is rotatable with respect to the casing in both directions of rotation.

Abstract: A one-way valve for medical infusion lines includes a first tubular connector and a second tubular connector, which define, respectively, an upstream passage and a downstream passage, which are coaxial and set transversely between which is a diaphragm made of elastically deformable material co-operating in a fluid-tight way with an annular seat to keep the valve normally closed. A filter, integrated in the valve, is axially clamped and blocked between the first tubular connector and the diaphragm.

Abstract: An injection site for tubular medical connectors, includes a perforable body inserted in a seat of a connector delimited by an annular wall having a retention edge turned in against the outer end of the perforable body. The outer end is formed with a peripheral annular step and with an exposed portion with reduced cross section projecting axially. The peripheral step is defined by an annular groove having a shape complementary to that of the turned-in retention edge of the connector, and the portion with reduced cross section of the perforable body connects up to the groove through an annular surface projecting radially above at least part of the turned-in retention edge and resting against it.

Abstract: A connector for medical lines includes a tubular body having a male luer-lock fitting at one end, intended to be screw-coupled with a complementary female fitting. An outer jacket is coupled in unidirectional rotation with the tubular body in the direction corresponding to the screwing of the male fitting and freely rotatable in the opposite direction. For selectively coupling the outer jacket with the tubular body in the direction corresponding to the unscrewing of the male fitting, at least one side push-button carried by said outer jacket is provided.

Abstract: A vial access device, includes a body having a projecting annular skirt that is elastically deformable, for engaging a complementary shaped neck of a vial. A tubular spike extends coaxially within the annular skirt for introducing into the vial, and a tubular connector protrudes from the body on the side opposite to the annular skirt and in fluid communication with the tubular spike. The tubular spike and the annular skirt are arranged, respectively, within a first and a second part, distinct from each other, and of which the first part is permanently joined to the body and the second part is connectable to the first part through an irreversible coupling.

Abstract: A flow system for medical lines includes a flow component having a main duct and at least one lateral tubular fitting with a female luer cone communicating with the main duct) through a valve. The valve includes a transverse diaphragm normally kept in fluid-tight contact against an annular valve seat of the lateral tubular fitting, which can be moved away from this into an opening position following upon insertion of a male luer-cone introducer of fluid into the lateral tubular fitting. The diaphragm is prearranged for being pushed into the opening position directly by the introducer, and the lateral tubular fitting is configured to couple in a fluid-tight way with the introducer before the latter comes into contact of thrust with the diaphragm.

Abstract: A vial access device is described comprising an upper housing having a fluid connecter in fluid communication with the upper housing; a vial access spike projecting from the upper housing; a fluid filter body within the upper housing or connectable thereto, the fluid filter body in fluid communication with the vial access spike and the fluid connector. Methods of reducing or eliminating particulate matter from medicament solutions are also provided.

Abstract: A medical device, particularly for mixing medical fluids, includes two tubular bodies made of materials of different elasticity having respective open ends to be joined together. The end of the second body is inserted axially by friction within the end of the first body and is then blocked via radial projections, which are obtained by plastic deformation of the wall of the end of the first body and are engaged against the end of the second body.

Abstract: An injection site for medical lines includes a tubular body made of molded plastic material within which an elastic element made of thermoplastic material is overmolded on an enlarged end of the tubular body. The enlarged end delimits an inner annular flange and is formed with at least one radial through-hole through which the elastic element is overmolded in order to rest axially against the inner annular flange and fill the radial through-hole with an appendage.

Abstract: A connector for medical infusion lines, transfusion lines, and the like, includes a tubular body having at one end a male connector including an inner tubular element and an outer hollow element, which is internally threaded and can be coupled by screwing to a complementary female connector. The line connector further includes an outer maneuvering sleeve coupled in unidirectional rotation to the body in the direction corresponding to screwing of the male connector with respect to the complementary female connector and free to turn in the opposite direction, formed by two parts coupled together on the body of the connector.