Abstract: The present disclosure relates to a novel PLK1 degradation inducing compound, a method for preparing the same, and the use thereof. The compounds of the present disclosure exhibit an effect of inducing PLK1 degradation. Therefore, the compounds of the present disclosure may be effectively utilized for preventing or treating PLK1-related diseases.

Abstract: The present disclosure relates to a novel PLK1 degradation inducing compound, a method for preparing the same, and the use thereof. The compounds of the present disclosure exhibit an effect of inducing PLK1 degradation. Therefore, the compounds of the present disclosure may be effectively utilized for preventing or treating PLK1-related diseases.

Abstract: The method of operating an image device comprises receiving an input of virtual tissues modeled with an arbitrary shape and a quantitative feature, simulating a TOF change or a signal strength change of ultrasound data having penetrated the virtual tissues modeled with a speed-of-sound distribution or an attenuation coefficient distribution in a first and in a second direction, and creating an image pair representing the TOF change or the signal strength change, creating a speed-of-sound distribution image or an attenuation coefficient distribution image of each of the virtual tissues as a ground truth of an image pair created in the corresponding virtual tissue, and training a first neural network that reconstruct the speed-of-sound distribution image from an input image pair or training a second neural network that reconstructs the attenuation coefficient distribution image from the input image pair.

Abstract: A method of operating an image device operated by at least one processor is provided. The method of operating an image device comprises generating beamformed RF-mode images including phase shift information for each incident angle by using multi-angle ultrasound-echo data, generating phase shift maps representing a displacement of speckle pattern between adjacent beamformed RF-mode images, and obtaining a speed-of-sound distribution image corresponding to the phase shift maps by using a deep neural network which is trained to reconstruct speed-of-sound distribution of a tissue from training phase shift maps.

Abstract: A hybrid power system including one or more base members configured to be installed at the seabed, one or more connecting members each coupled to a corresponding base member so as to be slidable in a vertical direction which is perpendicular to a top surface of the corresponding base member, a buoy configured to move in the vertical direction by receiving at least one of the wave force and current force, the buoy coupled to the top of the connecting member to move in conjunction with the one or more connecting members, and a power generation unit configured to generate electricity using vertical movement of the connecting members, the power generation unit installed in at least one of the one or more base members.

Abstract: A hybrid power system including one or more base members configured to be installed at the seabed, one or more connecting members each coupled to a corresponding base member so as to be slidable in a vertical direction which is perpendicular to a top surface of the corresponding base member, a buoy configured to move in the vertical direction by receiving at least one of the wave force and current force, the buoy coupled to the top of the connecting member to move in conjunction with the one or more connecting members, and a power generation unit configured to generate electricity using vertical movement of the connecting members, the power generation unit installed in at least one of the one or more base members.