Patents by Inventor Gidon Pilarski

Gidon Pilarski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of fluoxetine and new intermediates
    Patent number: 5225585
    Abstract: 4-methyl-3-[(4-trifluormethyl)phenoxy]-3-phenyl propylamine (I) is prepared by reacting 3-dimethylamino-1-phenyl-1-propanol (III) with haloformate (VIII) to obtain a substituted propyl carbamate (IX) which is hydrolyzed under basic conditions to yield methylamino-1-phenyl-1-propanol (X). The methylamino-1-phenyl-1-propanol is then converted to fluoxetine (I) by reaction with 4-halobenzotrifluoride (XI).In the process certain substituted carbamates are obtained as intermediates.
    Type: Grant
    Filed: August 18, 1992
    Date of Patent: July 6, 1993
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Eduard Schwartz, Joseph Kaspi, Zinovi Itov, Gidon Pilarski