Patents by Inventor Giedrius Vilkaitis

Giedrius Vilkaitis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11008605
    Abstract: Provided is a method for modifying a ssRNA at the 3? end, the method including contacting the strand with a ssRNA 2?-O-methyltransferase in the presence of a co-factor, under conditions which allow for the transfer by the ssRNA 2?-O-methyltransferase of a part of the co-factor onto the 3? end of the ssRNA to form a modified ssRNA, wherein the ssRNA bears 2?-OH group at 3? terminal nucleotide and wherein the part of the co-factor transferred includes a reporter group or a functional group.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: May 18, 2021
    Assignee: Vilnius University
    Inventors: Saulius Klimasauskas, Giedrius Vilkaitis, Milda Mickute
  • Publication number: 20180251814
    Abstract: Provided is a method for modifying a ssRNA at the 3? end, said method comprising contacting the strand with a ssRNA 2?-O-methyltransferase in the presence of a co-factor, under conditions which allow for the transfer by the ssRNA 2?-O-methyltransferase of a part of the co-factor onto 3? end of the ssRNA to form a modified ssRNA, wherein the ssRNA bears 2?-OH group at 3? terminal nucleotide and wherein the part of the co-factor transferred comprises a reporter group or a functional group.
    Type: Application
    Filed: March 18, 2016
    Publication date: September 6, 2018
    Inventors: Saulius KLIMASAUSKAS, Giedrius VILKAITIS, Milda MICKUTE
  • Publication number: 20150259725
    Abstract: A method for modifying a strand of RNA at the 3? end, includes contacting the strand with a RNA 2?-O-methyltransferase in the presence of a co-factor, under conditions which allow for the transfer by the RNA 2?-O-methyltransferase of a part of the co-factor onto the 3? end of the RNA strand to form a modified RNA strand, wherein the strand of RNA is included in a duplex, and wherein the part of the co-factor transferred includes a reporter group or a functional group.
    Type: Application
    Filed: May 30, 2013
    Publication date: September 17, 2015
    Inventors: Saulius Klimasauskas, Giedrius Vilkaitis, Aleksandra Plotnikova