Patents by Inventor Gijsbert Gerritse
Gijsbert Gerritse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8809032Abstract: This invention relates to amylase polypeptides, and nucleic acids encoding the polypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically the amylases of the current invention show an altered exospecifity.Type: GrantFiled: February 1, 2008Date of Patent: August 19, 2014Assignee: Dupont Nutrition Biosciences ApsInventors: Casper Tune Berg, Kirsten Bojsen, Patrick M. F. Derkx, Carol Fioresi, Gijsbert Gerritse, Karsten Matthias Kragh, Wei Liu, Andrew Shaw, Charlotte Refdahl Thoudahl, Anja Hemmingsen Kellett-Smith
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Patent number: 8143048Abstract: This invention relates to amylase polypeptides, and nucleic acids encoding the polpypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically, the amylases of the current invention show an altered exospecifity.Type: GrantFiled: July 7, 2004Date of Patent: March 27, 2012Assignee: Danisco A/SInventors: Karsten Matthias Kragh, Kirsten Bojsen, Casper Tune Berg, Patrick M. F. Derkx, Anja H. Kellett-Smith, Charlotte Refdahl Thoudahl, Carol Fioresi, Wei Liu, Andrew Shaw, Gijsbert Gerritse
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Patent number: 8137944Abstract: Variant polypeptides derivable from a parent polypeptide having non-maltogenic exoamylase activity, in which the variant polypeptides comprise an amino acid mutation at one or more positions selected from the group consisting of: 121, 161, 223, 146, 157, 158, 198, 229, 303, 306, 309, 316, 353, 26, 70, 145, 188, 272, 339, with reference to the position numbering of a Pseudomonas saccharophila exoamylase sequence shown as SEQ ID NO: 1.Type: GrantFiled: July 7, 2005Date of Patent: March 20, 2012Assignee: Danisco A/SInventors: Casper Tune Berg, Patrick M. F. Derkx, Carol Fioresi, Gijsbert Gerritse, Anja Hemmingen Kellet-Smith, Karsten Matthias Kragh, Wei Liu, Andrew Shaw, Bo Spange Sørensen, Charlotte Refdahl Thoudahl
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Patent number: 8129511Abstract: This invention relates to nucleic acids encoding amylase polypeptides, the encoded polypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically, the amylases of the current invention show an altered exo-specificity and/or thermostability. Some embodiments of the invention relate to said polypeptides and nucleic acids and their uses as non-maltogenic exoamylases in producing food products.Type: GrantFiled: February 8, 2011Date of Patent: March 6, 2012Assignee: Danisco A/SInventors: Karsten Matthias Kragh, Bo Spange Sørensen, Casper Tune Berg, Kirsten Bojsen, Patrick M. F. Derkx, Carol Fioresi, Anja H. Kellett-Smith, Charlotte Refdahl Thoudahl, Oene R. Veltman, Gijsbert Gerritse, Wei Liu, Andrew Shaw
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Patent number: 8030050Abstract: The invention describes a PS4 variant polypeptide derivable from a parent polypeptide having amylase activity selected from the group consisting of: (a) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 146, 157, 161, 178, 179, 223, 229, 272, 303, 307, 309 and 334; (b) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 145, 146, 157, 178, 179, 223, 229, 272, 303, 307 and 334; (c) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 146, 157, 178, 179, 223, 229, 272, 303, 307, 309 and 334; and (d) a polypeptide comprising an amino acid mutation at each of positions 3, 33, 34, 70, 121, 134, 141, 146, 157, 178, 179, 223, 229, 272, 303, 307, 309 and 334; with reference to the position numbering of a Pseudomonas saccharophilia exoamylase sequence shown as SEQ ID NO: 1, uses of such a polypeptide as a food or feed additive, and nucleic acids encoding such.Type: GrantFiled: September 22, 2006Date of Patent: October 4, 2011Assignee: Danisco A/SInventors: Casper Tune Berg, Patrick Maria Franciscus Derkx, Carol Fioresi, Gijsbert Gerritse, Anja Hemmingen Kellet-Smith, Karsten Matthias Kragh, Wei Liu, Andrew Shaw, Bo Spange Sørensen, Charlotte Refdahl Thoudahl
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Publication number: 20110212241Abstract: This invention relates to nucleic acids encoding amylase polypeptides, the encoded polypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically, the amylases of the current invention show an altered exo-specificity and/or thermostability. Some embodiments of the invention relate to said polypeptides and nucleic acids and their uses as non-maltogenic exoamylases in producing food products.Type: ApplicationFiled: February 8, 2011Publication date: September 1, 2011Inventors: Karsten Matthias Kragh, Bo Spange Sørensen, Casper Tune Berg, Kirsten Bojsen, Patrick M.F. Derkx, Carol Fioresi, Anja H. Kellett-Smith, Charlotte Refdahl Thoudahl, Oene R. Veltman, Gijsbert Gerritse, Wei Liu, Andrew Shaw
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Patent number: 7833770Abstract: This is invention relates to amylase polypeptides, and nucleic acids encoding the polypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically, the amylases of the current invention show an altered thermostability.Type: GrantFiled: September 27, 2006Date of Patent: November 16, 2010Assignee: Danisco A/SInventors: Karsten Matthias Kragh, Casper Tune Berg, Patrick M. F. Derkx, Anja H. Kellett-Smith, Charlotte Refdahl Thoudahl, Oene R. Veltman, Carol Fioresi, Gijsbert Gerritse, Wei Liu, Andrew Shaw
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Patent number: 7776576Abstract: This invention relates to amylase polypeptides, and nucleic acids encoding the polpypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically, the amylases of the current invention show an altered thermostability.Type: GrantFiled: July 7, 2004Date of Patent: August 17, 2010Assignee: Danisco A/SInventors: Karsten Matthias Kragh, Casper Tune Berg, Patrick M. F. Derkx, Anja H. Kellett-Smith, Charlotte Refdahl Thoudahl, Oene R. Veltman, Carol Fioresi, Wei Liu, Andrew Shaw, Gijsbert Gerritse
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Publication number: 20090214706Abstract: We describe a PS4 variant polypeptide derivable from a parent polypeptide having non-maltogenic exoamylase activity, in which the PS4 variant polypeptide comprises an amino acid mutation at one or more positions selected from the group consisting of: 121, 161, 223, 146, 157, 158, 198, 229, 303, 306, 309, 316, 353, 26, 70, 145, 188, 272, 339, with reference to the position numbering of a Pseudomonas saccharophilia exoamylase sequence shown as SEQ ID NO: 1.Type: ApplicationFiled: July 7, 2005Publication date: August 27, 2009Inventors: Casper Tune Berg, Patrick M.F. Derkx, Carol Fioresi, Gijsbert Gerritse, Anja Hemmingen Kellet-Smith, Karsten Matthias Kragh, Wei Liu, Andrew Shaw, Bo Spange Sørensen, Charlotte Refdahl Thoudahl
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Publication number: 20080292747Abstract: Described is a PS4 variant polypeptide derivable from a polypeptide having amylase activity selected from: (a) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 146, 157, 161, 178, 179, 223, 229, 272, 303, 307, 309 and 334; (b) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 145, 146, 157, 178, 179, 223, 229, 272, 303, 307 and 334; (c) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 146, 157, 178, 179, 223, 229, 272, 303, 307, 309 and 334; and (d) a polypeptide comprising an amino acid mutation at each of positions 3, 33, 34, 70, 121, 134, 141, 146, 157, 178, 179, 223, 229, 272, 303, 307, 309 and 334; referring to the numbering of a Pseudomonas saccharophilia exoamylase shown as SEQ ID NO: 1.Type: ApplicationFiled: January 7, 2008Publication date: November 27, 2008Inventors: Casper Tune Berg, Patrick Maria Franciscus Derkx, Carol Fioresi, Gijsbert Gerritse, Anja Hemmingen Kellet-Smith, Karsten Matthias Kragh, Wei Liu, Andrew Shaw, Bo Spange Sorensen, Charlotte Refdahl Thoudahl
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Publication number: 20080274531Abstract: This invention relates to amylase polypeptides, and nucleic acids encoding the polypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically the amylases of the current invention show an altered exospecifity.Type: ApplicationFiled: February 1, 2008Publication date: November 6, 2008Inventors: Casper Tune Berg, Kirsten Bojsen, Patrick M.F. Derkx, Carol Fioresi, Gijsbert Gerritse, Karsten Matthias Kragh, Wei Liu, Andrew Shaw, Charlotte Refdahl Thoudahl, Anja Hemmingsen Kellett-Smith
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Publication number: 20080227173Abstract: The invention describes a PS4 variant polypeptide derivable from a parent polypeptide having amylase activity selected from the group consisting of: (a) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 146, 157, 161, 178, 179, 223, 229, 272, 303, 307, 309 and 334; (b) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 145, 146, 157, 178, 179, 223, 229, 272, 303, 307 and 334; (c) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 146, 157, 178, 179, 223, 229, 272, 303, 307, 309 and 334; and (d) a polypeptide comprising an amino acid mutation at each of positions 3, 33, 34, 70, 121, 134, 141, 146, 157, 178, 179, 223, 229, 272, 303, 307, 309 and 334; with reference to the position numbering of a Pseudomonas saccharophilia exoamylase sequence shown as SEQ ID NO: 1, uses of such a polypeptide as a food or feed additive, and nucleic acids encoding such.Type: ApplicationFiled: September 22, 2006Publication date: September 18, 2008Inventors: Casper Tune BERG, Patrick Maria Franciscus Derkx, Carol Fioresi, Gijsbert Gerritse, Anja Hemmingen Kellet-Smith, Karsten Matthias Kragh, Wei Liu, Andrew Shaw, Bo Spange Sorensen, Charlotte Refdahl Thoudahl
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Publication number: 20070141693Abstract: The invention provides for a PS4 variant polypeptide derivable from a parent polypeptide having amylase activity which may be selected from the group consisting of: (a) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 146, 157, 161, 178, 179, 223, 229, 272, 303, 307, 309 and 334; (b) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 145, 146, 157, 178, 179, 223, 229, 272, 303, 307 and 334; (c) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 146, 157, 178, 179, 223, 229, 272, 303, 307, 309 and 334; and (d) a polypeptide comprising an amino acid mutation at each of positions 3, 33, 34, 70, 121, 134, 141, 146, 157, 178, 179, 223, 229, 272, 303, 307, 309 and 334; with reference to the position numbering of a Pseudomonas saccharophilia exoamylase sequence shown as SEQ ID NO: 1, uses of such a polypeptide as a food or feed additive, and nucleic acids encoding such.Type: ApplicationFiled: July 7, 2006Publication date: June 21, 2007Inventors: Casper Berg, Patrick Maria Derkx, Carol Fioresi, Gijsbert Gerritse, Anja Kellet-Smith, Karsten Kragh, Wei Liu, Andrew Shaw, Bo Sorensen, Charlotte Thoudahl
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Publication number: 20070020727Abstract: This invention relates to amylase polypeptides, and nucleic acids encoding the polpypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically, the amylases of the current invention show an altered exospecifity.Type: ApplicationFiled: September 19, 2006Publication date: January 25, 2007Inventors: Casper Berg, Kirsten Bojsen, Patrick Derkx, Carol Fioresi, Gijsbert Gerritse, Karsten Kragh, Wei Liu, Andrew Shaw, Charlotte Thoudahl, Anja Kellett-Smith
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Publication number: 20070020731Abstract: This is invention relates to amylase polypeptides, and nucleic acids encoding the polpypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically, the amylases of the current invention show an altered thermostability.Type: ApplicationFiled: September 27, 2006Publication date: January 25, 2007Inventors: Karsten Kragh, Casper Berg, Patrick Derkx, Anja Kellett-Smith, Charlotte Thoudahl, Oene Veltman, Carol Fioresi, Gijsbert Gerritse, Wei Liu, Andrew Shaw
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Publication number: 20050136524Abstract: This invention relates to amylase polypeptides, and nucleic acids encoding the polpypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically, the amylases of the current invention show an altered exospecifity.Type: ApplicationFiled: July 7, 2004Publication date: June 23, 2005Inventors: Karsten Kragh, Kirsten Bojsen, Casper Berg, Patrick Derkx, Anja Kellett-Smith, Charlotte Thoudahl, Carol Fioresi, Wei Liu, Andrew Shaw, Gijsbert Gerritse
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Publication number: 20050137111Abstract: This invention relates to amylase polypeptides, and nucleic acids encoding the polpypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically, the amylases of the current invention show an altered thermostability.Type: ApplicationFiled: July 7, 2004Publication date: June 23, 2005Inventors: Karsten Kragh, Casper Berg, Patrick Derkx, Anja Kellett-Smith, Charlotte Thoudahl, Oene Veltman, Carol Fioresi, Wei Liu, Andrew Shaw, Gijsbert Gerritse
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Patent number: 6313283Abstract: A new expression system is provided which comprises component(s) of a lipase regulation cascade. the lipase regulation cascade as disclosed herein includes a kinase, a DNA binding regulator, a polymerase, a promoter, an upstream activating sequence, and secretion factors. Plasmids and transformed cells are also provided as well as methods of transforming host cells using the plasmids. Further, there is provided a kinase that can regulate the expression of a protein, a DNA binding regulator that can regulate the expression of a protein, a Pseudomonas alcaligenes polymerase, a Pseudomonas alcaligenes sigma 54 promoter, a Pseudomonas alcaligenes upstream activating sequence, the Pseudomonas alcaligenes secretion factors XcpP, XcpQ, XcpR, XcpS, XcpT, XcpU, XcpV, XcpW, XcpX, XcpY, XcpZ and the xcp regulators OrfV, OrfX.Type: GrantFiled: January 6, 2000Date of Patent: November 6, 2001Assignee: Genencor International, Inc.Inventors: Gijsbert Gerritse, Wilhelmus J. Quax
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Patent number: 6225106Abstract: A new expression system is provided which comprises component(s) of a lipase regulation cascade. The lipase regulation cascade as disclosed herein includes a kinase, a DNA binding regulator, a polymerase, a promoter, an upstream activating sequence, and secretion factors. Plasmids and transformed cells are also provided as well as methods of transforming host cells using the plasmids. Further, there is provided a kinase that can regulate the expression of a protein, a DNA binding regulator that can regulate the expression of a protein, a Pseudomonas alcaligenes polymerase, a Pseudomonas alcaligenes sigma 54 promoter, a Pseudomonas alcaligenes upstream activating sequence, the Pseudomonas alcaligenes secretion factors XcpP, XcpQ, XcpR, XcpS, XcpT, XcpU, XcpV, XcpW, XcpX, XcpY, XcpZ and the xcp regulators OrfV, OrfX.Type: GrantFiled: January 6, 2000Date of Patent: May 1, 2001Assignee: Genencor International, Inc.Inventors: Gijsbert Gerritse, Wilhelmus J. Quax
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Patent number: 6048710Abstract: A new expression system is provided which comprises component(s) of a lipase regulation cascade. the lipase regulation cascade as disclosed herein includes a kinase, a DNA binding regulator, a polymerase, a promoter, an upstream activating sequence, and secretion factors. Plasmids and transformed cells are also provided as well as methods of transforming host cells using the plasmids. Further, there is provided a kinase that can regulate the expression of a protein, a DNA binding regulator that can regulate the expression of a protein, a Pseudomonas alcaligenes polymerase, a Pseudomonas alcaligenes sigma 54 promoter, a Pseudomonas alcaligenes upstream activating sequence, the Pseudomonas alcaligenes secretion factors XcpP, XcpQ, XcpR, XcpS, XcpT, XcpU, XcpV, XcpW, XcpX, XcpY, XcpZ and the xcp regulators OrfV, OrfX.Type: GrantFiled: August 15, 1997Date of Patent: April 11, 2000Assignee: Genecor International, Inc.Inventors: Gijsbert Gerritse, Wilhelmus J. Quax