Abstract: Described herein are compositions and methods for treating cancer of a body cavity, specifically urinary tract cancer, by way of a combination of at least two immunomodulatory agents, wherein one or more of the therapeutic agents are embedded in, and slowly released from, a biocompatible hydrogel composition.

Abstract: There are provided a connectable catheter system, device and methods of use thereof. The connectable catheter system, comprising: an intermediary catheter comprising an external section and a tip section, the tip section is configured to be inserted into a body of a subject; and a reconnectable indwelling stent comprising a connecting section and a target section, the target section being configured to be located within a body of the subject, wherein the connecting section of the reconnectable indwelling stent is configured to reversibly connect, within the subject body, to the tip section of the intermediary catheter to form a continuous conduit between the intermediary catheter and the reconnectable indwelling stent.

Abstract: Described herein are compositions and methods for treating cancer of a body cavity, specifically urinary tract cancer, by way of a combination of at least two immunomodulatory agents, wherein one or more of the therapeutic agents are embedded in, and slowly released from, a biocompatible hydrogel composition.

Abstract: Described herein are compositions and methods for treating cancer of a body cavity, specifically urinary tract cancer, by way of a combination of at least two immunomodulatory agents, wherein one or more of the therapeutic agents are embedded in, and slowly released from, a biocompatible hydrogel composition.

Abstract: Disclosed herein are materials, means and methods for sustained release of therapeutic agents for topical treatments. In particular, disclosed are means and methods for topical treatment of diseases of internal body cavities by embedding therapeutic agents in a slowly degrading biocompatible mixture applied to affected tissue.

Abstract: Described herein are compositions and methods for treating cancer of a body cavity, specifically urinary tract cancer, by way of a combination of at least two immunomodulatory agents, wherein one or more of the therapeutic agents are embedded in, and slowly released from, a biocompatible hydrogel composition.

Abstract: There are provided a connectable catheter system, device and methods of use thereof. The connectable catheter system, comprising: an intermediary catheter and a reconnectable indwelling stent wherein the intermediary catheter and the indwelling stent are configured to connect, within a subject body to form a continuous fluid conduit between the intermediary catheter and the reconnectable indwelling stent and to further allow controlled release of substances and/or heating of internal target regions.

Abstract: A method and device producing extracorporeal shockwaves for the treatment of erectile dysfunction

Abstract: A method and device producing extracorporeal shockwaves for the treatment of erectile dysfunction.

Abstract: Provided herein are methods for treating cancer of a body cavity, including specifically urinary tract cancer, by way of at least one cell cycle regulator, and at least one anti-cancer drug for local treatment; wherein the therapeutic agents are embedded in, and slowly released from, a biocompatible hydrogel composition.

Abstract: A method is disclosed for production of a sterile thermoreversible hydrogel characterized by a known temperature Tmin at which the viscosity reaches at least a local minimum. In a preferred embodiment of the invention, the method comprises dissolving the components in water within ±4° C. of Tmin; forming the thermoreversible hydrogel; and filtering the thermoreversible hydrogel at Tmin. The final sterilization can be obtained by filtering under aseptic conditions or by autoclaving or irradiation of the final product. In other embodiments, the components of the gel are dissolved in a sufficiently large quantity of water that reduces the gel viscosity or precludes formation of a thermoreversible hydrogel, and sufficient water is then removed under vacuum to produce the final thermoreversible hydrogel.

Abstract: There are provided a connectable catheter system, device and methods of use thereof. The connectable catheter system, comprising: an intermediary catheter comprising an external section and a tip section, the tip section is configured to be inserted into a body of a subject; and a reconnectable indwelling stent comprising a connecting section and a target section, the target section being configured to be located within a body of the subject, wherein the connecting section of the reconnectable indwelling stent is configured to reversibly connect, within the subject body, to the tip section of the intermediary catheter to form a continuous conduit between the intermediary catheter and the reconnectable indwelling stent.

Abstract: A system for controlling and modulating a mammalian's body temperature and thermoregulation system includes: a. a display monitor; b. a pulse generator; c. at least one channel of electrical or electromagnetic stimuli connected to the pulse generator, and adapted for cutaneous application on the body's spinal cord; d. a control panel, and e. at least one Measurement Analysis and Command (MAC) unit. The control panel and the MAC units are adapted to implement the optimal stimulating procedure for blocking the afferent neural pathways, evoking the afferent neural pathways, attenuating the afferent neural pathways, blocking and evoking the efferent neural pathways, blocking and attenuating the efferent neural pathways, attenuating and evoking, or blocking, attenuating, and evoking the efferent neural pathways, involved in the thermoregulation system, thereby controlling and modulating the body's temperature and thermoregulation system.

Abstract: A method is disclosed for production of a sterile thermoreversible hydrogel characterized by a known temperature Tmin at which the viscosity reaches at least a local minimum. In a preferred embodiment of the invention, the method comprises dissolving the components in water within ±4° C. of Tmin; forming the thermoreversible hydrogel; and filtering the thermoreversible hydrogel at Tmin. The final sterilization can be obtained by filtering under aseptic conditions or by autoclaving or irradiation of the final product. In other embodiments, the components of the gel are dissolved in a sufficiently large quantity of water that reduces the gel viscosity or precludes formation of a thermoreversible hydrogel, and sufficient water is then removed under vacuum to produce the final thermoreversible hydrogel.

Abstract: Disclosed herein are materials, means and methods for sustained release of therapeutic agents for topical treatments. In particular, disclosed are means and methods for topical treatment of diseases of internal body cavities by embedding therapeutic agents in a slowly degrading biocompatible mixture applied to affected tissue.

Abstract: A method and device producing extracorporeal shockwaves for the treatment of erectile dysfunction.