Patents by Inventor Gil Lee

Gil Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250244340
    Abstract: The present disclosure contemplates detecting and treating a pathological condition, such as intestinal ischemia such as acute mesenteric ischemia, necrotizing enterocolitis, inflammatory bowel disease, and bowel graft rejection in a subject's intestinal tract. The methodology comprises obtaining a sample from the subject; detecting whether an analyte such as Villin-1, ?-glutathione S-transferase, or intestinal fatty acid binding protein (I-FABP) is present in the sample by contacting the sample with an anti-analyte antibody and detecting binding between analyte and the antibody; and diagnosing the subject with the condition when, for example, the presence of analyte in the sample is detected and exceeds the level of analyte in a healthy control sample. A superparamagnetic bead includes an anti-Villin-1 antibody; an anti-?-glutathione S-transferase antibody, or an anti-intestinal-fatty acid binding protein (I-FABP) antibody.
    Type: Application
    Filed: June 24, 2023
    Publication date: July 31, 2025
    Inventors: Peng LI, Gil LEE, Anne CHEVALIER
  • Patent number: 11273454
    Abstract: There is provided system and a separation substrate device for use with an NLM separator in separating and/or detecting at least one target analyte in a sample, the substrate comprising a micromagnet array of a plurality of micromagnets, the micromagnet array comprising a first capture region, a second focusing region, and, a third detection region, the focusing region comprising a converging and/or diverging micromagnet array region. Also provided is a method for separating and detecting at least one target analyte in a sample.
    Type: Grant
    Filed: July 4, 2016
    Date of Patent: March 15, 2022
    Assignee: University College Dublin, National University of Ireland, Dublin
    Inventors: Devrim Kilinc, Peng Li, Gil Lee, Dhruv Ghandi, Stefano Rampini
  • Patent number: 10436777
    Abstract: A method for detecting an analyte in a sample, the method comprising contacting the analyte in a sample with nanoparticles comprising a capture probe for capturing said analyte, the capture probe being configured to act as a center for controlled aggregation of nanoparticles with said analyte to form an aggregate of predefined form, detecting the analyte by detecting the shape and/or size of the aggregate is provided. Also provided are nanoparticles comprising a capture probe for capturing an analyte, wherein the capture probe is configured to act as a center for controlled aggregation of nanoparticles with the analyte to form an aggregate of particular detectable size and/or shape, and an assay.
    Type: Grant
    Filed: December 5, 2012
    Date of Patent: October 8, 2019
    Assignee: University College Dublin, National University of Ireland, Dublin
    Inventors: Gil Lee, Mark Platt
  • Patent number: 10386364
    Abstract: There is provided a method of aggregating a plurality of beads in a magnetic bead aggregation assay for subsequent analysis comprising: —providing magnetic beads comprising a capture probe for binding with said target analyte; —reacting the magnetic beads with the sample including a target analyte in a reaction chamber aggregating the magnetic beads in the presence of a magnetic field with the target analyte to allow formation of magnetic bead aggregates having physical properties detectable to enable characterization of the aggregates on an aggregate by aggregate basis using a detector to measure the physical properties of the aggregates. Further provided are a method and system for detecting analytes in a sample by characterizing the magnetic bead aggregates on an aggregate by aggregate basis by measuring physical properties of the aggregates.
    Type: Grant
    Filed: July 9, 2012
    Date of Patent: August 20, 2019
    Assignee: University College Dublin, National University of Ireland, Dublin
    Inventors: Gil Lee, Peng Li, Mark Platt, Gemma Cannon
  • Publication number: 20180361396
    Abstract: There is provided system and a separation substrate device for use with an NLM separator in separating and/or detecting at least one target analyte in a sample, the substrate comprising a micromagnet array of a plurality of micromagnets, the micromagnet array comprising a first capture region, a second focussing region, and, a third detection region, the focussing region comprising a converging and/or diverging micromagnet array region. Also provided is a method for separating and detecting at least one target analyte in a sample.
    Type: Application
    Filed: July 4, 2016
    Publication date: December 20, 2018
    Inventors: Devrim KILINC, Peng LI, Gil LEE, Dhruv GHANDI, Stefano RAMPINI
  • Patent number: 10005677
    Abstract: There is provided a method of producing microparticles using an emulsion based synthesis route including: Providing a first fluid phase and a second fluid phase, wherein the first fluid phase is a continuous phase and the second fluid phase is a dispersed phase comprising a dispersed material, wherein the continuous phase is immiscible with the dispersed phase; Mixing the first continuous phase and the second dispersed phase in the presence of a surfactant in a shear device to form an emulsion of droplets of controllable size and having a narrow drop size distribution; Drying the emulsion to form microparticles of controllable size and having narrow size distribution, and wherein the microparticles may comprise spherical, crumpled, dimpled, porous or hollow microparticles morphology. Also provided is a system including shear device and drying arrangement. Also provided are micro particles of controllable size and morphology formed by the method.
    Type: Grant
    Filed: May 31, 2013
    Date of Patent: June 26, 2018
    Assignee: University College Dublin, National University of Ireland, Dublin
    Inventors: Gil Lee, Mark Platt, James O'Mahony
  • Patent number: 9421555
    Abstract: A flow enhanced method and system for flow non-linear magnetophoresis (F-NLM) is described. By tuning an external field frequency and the flow rate the migration velocities of different bead types may be caused to differ by several orders of magnitude over an extended range of frequencies to allow for separation of particles. Use of such efficiency in separation in bio-separation and similar assays is described.
    Type: Grant
    Filed: July 7, 2011
    Date of Patent: August 23, 2016
    Assignee: University College Dublin, National University of Ireland
    Inventors: Gil Lee, Peng Li, Mark Platt, Gemma Cannon
  • Publication number: 20150183655
    Abstract: There is provided a method of producing microparticles using an emulsion based synthesis route including: Providing a first fluid phase and a second fluid phase, wherein the first fluid phase is a continuous phase and the second fluid phase is a dispersed phase comprising a dispersed material, wherein the continuous phase is immiscible with the dispersed phase; Mixing the first continuous phase and the second dispersed phase in the presence of a surfactant in a shear device to form an emulsion of droplets of controllable size and having a narrow drop size distribution; Drying the emulsion to form microparticles of controllable size and having narrow size distribution, and wherein the microparticles may comprise spherical, crumpled, dimpled, porous or hollow microparticles morphology. Also provided is a system including shear device and drying arrangement. Also provided are micro particles of controllable size and morphology formed by the method.
    Type: Application
    Filed: May 31, 2013
    Publication date: July 2, 2015
    Applicant: University College Dublin, National University of Ireland, Dublin
    Inventors: Gil Lee, Mark Platt, James O'Mahony
  • Publication number: 20140315328
    Abstract: A method for detecting an analyte in a sample, the method comprising contacting the analyte in a sample with nanoparticles comprising a capture probe for capturing said analyte, the capture probe being configured to act as a centre for controlled aggregation of nanoparticles with said analyte to form an aggregate of predefined form, detecting the analyte by detecting the shape and/or size of the aggregate is provided. Also provided are nanoparticles comprising a capture probe for capturing an analyte, wherein the capture probe is configured to act as a centre for controlled aggregation of nanoparticles with the analyte to form an aggregate of particular detectable size and/or shape, and an assay.
    Type: Application
    Filed: December 5, 2012
    Publication date: October 23, 2014
    Inventors: Gil Lee, Mark Platt
  • Publication number: 20140227679
    Abstract: There is provided a method of aggregating a plurality of beads in a magnetic bead aggregation assay for subsequent analysis comprising: —providing magnetic beads comprising a capture probe for binding with said target analyte; —reacting the magnetic beads with the sample including a target analyte in a reaction chamber aggregating the magnetic beads in the presence of a magnetic field with the target analyte to allow formation of magnetic bead aggregates having physical properties detectable to enable characterisation of the aggregates on an aggregate by aggregate basis using a detector to measure the physical properties of the aggregates. Further provided are a method and system for detecting analytes in a sample by characterising the magnetic bead aggregates on an aggregate by aggregate basis by measuring physical properties of the aggregates.
    Type: Application
    Filed: July 9, 2012
    Publication date: August 14, 2014
    Applicant: University College Dublin, National University of Ireland, Dublin
    Inventors: Gil Lee, Peng Li, Mark Platt, Gemma Cannon
  • Patent number: 8752201
    Abstract: Provided are an apparatus and method for managing digital rights. An agent unit manages application programs to which DRM is to be applied and rights to contents processed by the application programs to which DRM is to be applied, and encrypt and decrypt the contents processed by the application programs. A rights management unit authenticates a user and manages a user right to the contents processed by the application programs. A kernel API hooking unit monitors input/output of a file through hooking kernel native APIs, requests the rights management unit to verify the user right to the contents to be processed, and requests the agent unit to encrypt or decrypt the contents when the user right to the contents to be processed is verified.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: June 10, 2014
    Assignee: Samsung SDS Co., Ltd.
    Inventors: Ki-Hyung Lee, Gil Lee, Heoung-Keun Moon, Hwan-Woon Yeo, Hwang-Hoo Kim, Joon-Cheol Park, Jae-Hee Park
  • Publication number: 20140021105
    Abstract: A flow enhanced method and system for flow non-linear magnetophoresis (F-NLM) is described. By tuning an external field frequency and the flow rate the migration velocities of different bead types may be caused to differ by several orders of magnitude over an extended range of frequencies to allow for separation of particles. Use of such efficiency in separation in bio-separation and similar assays is described.
    Type: Application
    Filed: July 7, 2011
    Publication date: January 23, 2014
    Inventors: Gil Lee, Peng Li, Mark Platt, Gemma Cannon
  • Publication number: 20120124642
    Abstract: Provided are apparatus and method for selectively decrypting and transmitting DRM contents. A policy storing unit stores information on devices allowed for decryption of contents. A policy processing unit determines whether a target device, to which an encrypted content is transmitted, is a device allowed for decryption based on the information stored in the policy storing unit. A decryption unit decrypts the encrypted content. And a control unit controls the decryption unit to decrypt the encrypted content when the target device is the device allowed for decryption.
    Type: Application
    Filed: November 17, 2011
    Publication date: May 17, 2012
    Applicant: SAMSUNG SDS CO., LTD.
    Inventors: Ki-Hyung LEE, Gil LEE, Heoung-Keun MOON, Hwan-Woon YEO, Hwang-Hoo KIM, Joon-Cheol PARK, Jae-Hee PARK
  • Publication number: 20120124675
    Abstract: Provided are an apparatus and method for managing digital rights. An agent unit manages application programs to which DRM is to be applied and rights to contents processed by the application programs to which DRM is to be applied, and encrypt and decrypt the contents processed by the application programs. A rights management unit authenticates a user and manages a user right to the contents processed by the application programs. A kernel API hooking unit monitors input/output of a file through hooking kernel native APIs, requests the rights management unit to verify the user right to the contents to be processed, and requests the agent unit to encrypt or decrypt the contents when the user right to the contents to be processed is verified.
    Type: Application
    Filed: November 11, 2011
    Publication date: May 17, 2012
    Applicant: SAMSUNG SDS CO., LTD.
    Inventors: Ki-Hyung LEE, Gil Lee, Heoung-Keun Moon, Hwan-Woon Yeo, Hwang-Hoo Kim, Joon-Cheol Park, Jae-Hee Park
  • Publication number: 20070264706
    Abstract: A sensor for a selected analyte in a test sample has (a) a semipermeable membrane with pores for retaining the analyte, where the membrane has been chemically modified by attachment of membrane modifiers; (b) immunoassay labels which have label binding ligands where these label binding ligands will have a binding affinity for the membrane modifiers in the presence of the analyte, and a measurably different binding affinity for the membrane modifiers in the absence of the analyte; and (c) a label detecting system, for detecting the presence of the labels on the membrane.
    Type: Application
    Filed: October 5, 2006
    Publication date: November 15, 2007
    Inventors: Gil Lee, Carolyn Yanavich
  • Publication number: 20070172426
    Abstract: Methods for preparing uniformly sized microparticles, with an optional polymeric coating generally include: 1) providing nanoparticles, preferably having a size of between 1 nm and 100 nm; 2) adding a hydrophobic surface layer to the nanoparticles; 3) making a suspension of the hydrophobic nanoparticles and a polymerization initiator in an hydrophobic solvent; 4) dissolving a monomer in the hydrophobic solvent; 5) making an emulsion by dispersing droplets of the hydrophobic solvent in a continuous aqueous phase with an emulsifier; 6) sizing the first emulsion to provide a second emulsion of the same basic components but in which the droplets are substantially uniform and between 2 and 20 ?m in size; 7) evaporating at least a substantial portion of the dispersed hydrophobic droplets to assemble nanoparticles to form microparticles suspended now in the aqueous phase; 8) optionally replacing the first surfactant with a second surfactant, which is preferably a polymerizable surfactant; 9) optionally adding a poly
    Type: Application
    Filed: October 24, 2006
    Publication date: July 26, 2007
    Inventors: Gil Lee, Hao Shang, Won-Suk Chang
  • Publication number: 20060275757
    Abstract: Biological material in a sample is reacted with a novel functionalized superparamagnetic Fe/Au nanoparticle that specifically binds to the biological material in solution to produce a magnetic particle/biological material complex. The biological material is detected upon application of an external magnetic field which separates the magnetic bound complex from other components of the reaction mixture.
    Type: Application
    Filed: June 30, 2003
    Publication date: December 7, 2006
    Inventors: Gil Lee, Ronald Andres
  • Publication number: 20060150840
    Abstract: The present invention discloses a digital textile printer including a front and a rear feeding devices driven by a transfer axis within a driving panel of the front and the rear of a base to prevent distortion and wrinkle phenomena generating defective printing to perform effectively the textile printing even to the very thin textile fabrics, an ink-retrieving hole along to the transfer axis on the top of thee base to collect the residues of the injected ink passing through a printing material to prevent ink from spreading at the printing material, at least one suction pan in the inside of the base to collect easily the residues of the injected ink to hasten dries of ink, and a heater of rubber material in the inside of the front of the base to hasten dries of the printing material passing through the ink-retrieving hole.
    Type: Application
    Filed: August 18, 2004
    Publication date: July 13, 2006
    Inventor: Gil Lee
  • Publication number: 20060043812
    Abstract: A PMA (Permanent Magnet Assisted) synRM and a method for imposing a magnetic force thereon. Magnets are inserted into outer flux barriers of a plurality of flux barriers formed along the radius of a rotor, and bridges or slim portions are formed on inner flux barriers at positions corresponding to the positions of the magnets so that the magnetic force is imposed on the magnets through coils. Since the number of the flux barriers is sufficiently increased while the amount of the magnets consumed is decreased, the PMA synRM has increased efficiency and reduced production costs.
    Type: Application
    Filed: January 4, 2005
    Publication date: March 2, 2006
    Applicant: LG Electronics Inc.
    Inventors: Dal Cheong, Kyung Lee, Hyun Shin, June Won, Jae Oh, Gil Lee
  • Publication number: 20060033457
    Abstract: A sensorless motor drive apparatus and a method for protecting and controlling the same. The sensorless motor drive apparatus includes a unit for determining the presence or absence of a position estimation error of a rotor contained in a motor using a current value applied to the motor and a position estimation angle of the rotor. Therefore, the sensorless motor drive apparatus determines the presence or absence of the position estimation error of the rotor without using a sensor, so that it reduces production costs, prevents the motor from generating a faulty operation, and prevents a compressor including the motor from being damaged.
    Type: Application
    Filed: January 19, 2005
    Publication date: February 16, 2006
    Applicant: LG Electronics Inc.
    Inventors: June Won, Jae Oh, Gil Lee, Dal Cheong