Patents by Inventor Gil Lee
Gil Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250244340Abstract: The present disclosure contemplates detecting and treating a pathological condition, such as intestinal ischemia such as acute mesenteric ischemia, necrotizing enterocolitis, inflammatory bowel disease, and bowel graft rejection in a subject's intestinal tract. The methodology comprises obtaining a sample from the subject; detecting whether an analyte such as Villin-1, ?-glutathione S-transferase, or intestinal fatty acid binding protein (I-FABP) is present in the sample by contacting the sample with an anti-analyte antibody and detecting binding between analyte and the antibody; and diagnosing the subject with the condition when, for example, the presence of analyte in the sample is detected and exceeds the level of analyte in a healthy control sample. A superparamagnetic bead includes an anti-Villin-1 antibody; an anti-?-glutathione S-transferase antibody, or an anti-intestinal-fatty acid binding protein (I-FABP) antibody.Type: ApplicationFiled: June 24, 2023Publication date: July 31, 2025Inventors: Peng LI, Gil LEE, Anne CHEVALIER
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Patent number: 11273454Abstract: There is provided system and a separation substrate device for use with an NLM separator in separating and/or detecting at least one target analyte in a sample, the substrate comprising a micromagnet array of a plurality of micromagnets, the micromagnet array comprising a first capture region, a second focusing region, and, a third detection region, the focusing region comprising a converging and/or diverging micromagnet array region. Also provided is a method for separating and detecting at least one target analyte in a sample.Type: GrantFiled: July 4, 2016Date of Patent: March 15, 2022Assignee: University College Dublin, National University of Ireland, DublinInventors: Devrim Kilinc, Peng Li, Gil Lee, Dhruv Ghandi, Stefano Rampini
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Patent number: 10436777Abstract: A method for detecting an analyte in a sample, the method comprising contacting the analyte in a sample with nanoparticles comprising a capture probe for capturing said analyte, the capture probe being configured to act as a center for controlled aggregation of nanoparticles with said analyte to form an aggregate of predefined form, detecting the analyte by detecting the shape and/or size of the aggregate is provided. Also provided are nanoparticles comprising a capture probe for capturing an analyte, wherein the capture probe is configured to act as a center for controlled aggregation of nanoparticles with the analyte to form an aggregate of particular detectable size and/or shape, and an assay.Type: GrantFiled: December 5, 2012Date of Patent: October 8, 2019Assignee: University College Dublin, National University of Ireland, DublinInventors: Gil Lee, Mark Platt
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Patent number: 10386364Abstract: There is provided a method of aggregating a plurality of beads in a magnetic bead aggregation assay for subsequent analysis comprising: —providing magnetic beads comprising a capture probe for binding with said target analyte; —reacting the magnetic beads with the sample including a target analyte in a reaction chamber aggregating the magnetic beads in the presence of a magnetic field with the target analyte to allow formation of magnetic bead aggregates having physical properties detectable to enable characterization of the aggregates on an aggregate by aggregate basis using a detector to measure the physical properties of the aggregates. Further provided are a method and system for detecting analytes in a sample by characterizing the magnetic bead aggregates on an aggregate by aggregate basis by measuring physical properties of the aggregates.Type: GrantFiled: July 9, 2012Date of Patent: August 20, 2019Assignee: University College Dublin, National University of Ireland, DublinInventors: Gil Lee, Peng Li, Mark Platt, Gemma Cannon
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Publication number: 20180361396Abstract: There is provided system and a separation substrate device for use with an NLM separator in separating and/or detecting at least one target analyte in a sample, the substrate comprising a micromagnet array of a plurality of micromagnets, the micromagnet array comprising a first capture region, a second focussing region, and, a third detection region, the focussing region comprising a converging and/or diverging micromagnet array region. Also provided is a method for separating and detecting at least one target analyte in a sample.Type: ApplicationFiled: July 4, 2016Publication date: December 20, 2018Inventors: Devrim KILINC, Peng LI, Gil LEE, Dhruv GHANDI, Stefano RAMPINI
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Patent number: 10005677Abstract: There is provided a method of producing microparticles using an emulsion based synthesis route including: Providing a first fluid phase and a second fluid phase, wherein the first fluid phase is a continuous phase and the second fluid phase is a dispersed phase comprising a dispersed material, wherein the continuous phase is immiscible with the dispersed phase; Mixing the first continuous phase and the second dispersed phase in the presence of a surfactant in a shear device to form an emulsion of droplets of controllable size and having a narrow drop size distribution; Drying the emulsion to form microparticles of controllable size and having narrow size distribution, and wherein the microparticles may comprise spherical, crumpled, dimpled, porous or hollow microparticles morphology. Also provided is a system including shear device and drying arrangement. Also provided are micro particles of controllable size and morphology formed by the method.Type: GrantFiled: May 31, 2013Date of Patent: June 26, 2018Assignee: University College Dublin, National University of Ireland, DublinInventors: Gil Lee, Mark Platt, James O'Mahony
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Patent number: 9421555Abstract: A flow enhanced method and system for flow non-linear magnetophoresis (F-NLM) is described. By tuning an external field frequency and the flow rate the migration velocities of different bead types may be caused to differ by several orders of magnitude over an extended range of frequencies to allow for separation of particles. Use of such efficiency in separation in bio-separation and similar assays is described.Type: GrantFiled: July 7, 2011Date of Patent: August 23, 2016Assignee: University College Dublin, National University of IrelandInventors: Gil Lee, Peng Li, Mark Platt, Gemma Cannon
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Publication number: 20150183655Abstract: There is provided a method of producing microparticles using an emulsion based synthesis route including: Providing a first fluid phase and a second fluid phase, wherein the first fluid phase is a continuous phase and the second fluid phase is a dispersed phase comprising a dispersed material, wherein the continuous phase is immiscible with the dispersed phase; Mixing the first continuous phase and the second dispersed phase in the presence of a surfactant in a shear device to form an emulsion of droplets of controllable size and having a narrow drop size distribution; Drying the emulsion to form microparticles of controllable size and having narrow size distribution, and wherein the microparticles may comprise spherical, crumpled, dimpled, porous or hollow microparticles morphology. Also provided is a system including shear device and drying arrangement. Also provided are micro particles of controllable size and morphology formed by the method.Type: ApplicationFiled: May 31, 2013Publication date: July 2, 2015Applicant: University College Dublin, National University of Ireland, DublinInventors: Gil Lee, Mark Platt, James O'Mahony
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Publication number: 20140315328Abstract: A method for detecting an analyte in a sample, the method comprising contacting the analyte in a sample with nanoparticles comprising a capture probe for capturing said analyte, the capture probe being configured to act as a centre for controlled aggregation of nanoparticles with said analyte to form an aggregate of predefined form, detecting the analyte by detecting the shape and/or size of the aggregate is provided. Also provided are nanoparticles comprising a capture probe for capturing an analyte, wherein the capture probe is configured to act as a centre for controlled aggregation of nanoparticles with the analyte to form an aggregate of particular detectable size and/or shape, and an assay.Type: ApplicationFiled: December 5, 2012Publication date: October 23, 2014Inventors: Gil Lee, Mark Platt
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Publication number: 20140227679Abstract: There is provided a method of aggregating a plurality of beads in a magnetic bead aggregation assay for subsequent analysis comprising: —providing magnetic beads comprising a capture probe for binding with said target analyte; —reacting the magnetic beads with the sample including a target analyte in a reaction chamber aggregating the magnetic beads in the presence of a magnetic field with the target analyte to allow formation of magnetic bead aggregates having physical properties detectable to enable characterisation of the aggregates on an aggregate by aggregate basis using a detector to measure the physical properties of the aggregates. Further provided are a method and system for detecting analytes in a sample by characterising the magnetic bead aggregates on an aggregate by aggregate basis by measuring physical properties of the aggregates.Type: ApplicationFiled: July 9, 2012Publication date: August 14, 2014Applicant: University College Dublin, National University of Ireland, DublinInventors: Gil Lee, Peng Li, Mark Platt, Gemma Cannon
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Patent number: 8752201Abstract: Provided are an apparatus and method for managing digital rights. An agent unit manages application programs to which DRM is to be applied and rights to contents processed by the application programs to which DRM is to be applied, and encrypt and decrypt the contents processed by the application programs. A rights management unit authenticates a user and manages a user right to the contents processed by the application programs. A kernel API hooking unit monitors input/output of a file through hooking kernel native APIs, requests the rights management unit to verify the user right to the contents to be processed, and requests the agent unit to encrypt or decrypt the contents when the user right to the contents to be processed is verified.Type: GrantFiled: November 11, 2011Date of Patent: June 10, 2014Assignee: Samsung SDS Co., Ltd.Inventors: Ki-Hyung Lee, Gil Lee, Heoung-Keun Moon, Hwan-Woon Yeo, Hwang-Hoo Kim, Joon-Cheol Park, Jae-Hee Park
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Publication number: 20140021105Abstract: A flow enhanced method and system for flow non-linear magnetophoresis (F-NLM) is described. By tuning an external field frequency and the flow rate the migration velocities of different bead types may be caused to differ by several orders of magnitude over an extended range of frequencies to allow for separation of particles. Use of such efficiency in separation in bio-separation and similar assays is described.Type: ApplicationFiled: July 7, 2011Publication date: January 23, 2014Inventors: Gil Lee, Peng Li, Mark Platt, Gemma Cannon
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Publication number: 20120124642Abstract: Provided are apparatus and method for selectively decrypting and transmitting DRM contents. A policy storing unit stores information on devices allowed for decryption of contents. A policy processing unit determines whether a target device, to which an encrypted content is transmitted, is a device allowed for decryption based on the information stored in the policy storing unit. A decryption unit decrypts the encrypted content. And a control unit controls the decryption unit to decrypt the encrypted content when the target device is the device allowed for decryption.Type: ApplicationFiled: November 17, 2011Publication date: May 17, 2012Applicant: SAMSUNG SDS CO., LTD.Inventors: Ki-Hyung LEE, Gil LEE, Heoung-Keun MOON, Hwan-Woon YEO, Hwang-Hoo KIM, Joon-Cheol PARK, Jae-Hee PARK
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Publication number: 20120124675Abstract: Provided are an apparatus and method for managing digital rights. An agent unit manages application programs to which DRM is to be applied and rights to contents processed by the application programs to which DRM is to be applied, and encrypt and decrypt the contents processed by the application programs. A rights management unit authenticates a user and manages a user right to the contents processed by the application programs. A kernel API hooking unit monitors input/output of a file through hooking kernel native APIs, requests the rights management unit to verify the user right to the contents to be processed, and requests the agent unit to encrypt or decrypt the contents when the user right to the contents to be processed is verified.Type: ApplicationFiled: November 11, 2011Publication date: May 17, 2012Applicant: SAMSUNG SDS CO., LTD.Inventors: Ki-Hyung LEE, Gil Lee, Heoung-Keun Moon, Hwan-Woon Yeo, Hwang-Hoo Kim, Joon-Cheol Park, Jae-Hee Park
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Publication number: 20070264706Abstract: A sensor for a selected analyte in a test sample has (a) a semipermeable membrane with pores for retaining the analyte, where the membrane has been chemically modified by attachment of membrane modifiers; (b) immunoassay labels which have label binding ligands where these label binding ligands will have a binding affinity for the membrane modifiers in the presence of the analyte, and a measurably different binding affinity for the membrane modifiers in the absence of the analyte; and (c) a label detecting system, for detecting the presence of the labels on the membrane.Type: ApplicationFiled: October 5, 2006Publication date: November 15, 2007Inventors: Gil Lee, Carolyn Yanavich
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Publication number: 20070172426Abstract: Methods for preparing uniformly sized microparticles, with an optional polymeric coating generally include: 1) providing nanoparticles, preferably having a size of between 1 nm and 100 nm; 2) adding a hydrophobic surface layer to the nanoparticles; 3) making a suspension of the hydrophobic nanoparticles and a polymerization initiator in an hydrophobic solvent; 4) dissolving a monomer in the hydrophobic solvent; 5) making an emulsion by dispersing droplets of the hydrophobic solvent in a continuous aqueous phase with an emulsifier; 6) sizing the first emulsion to provide a second emulsion of the same basic components but in which the droplets are substantially uniform and between 2 and 20 ?m in size; 7) evaporating at least a substantial portion of the dispersed hydrophobic droplets to assemble nanoparticles to form microparticles suspended now in the aqueous phase; 8) optionally replacing the first surfactant with a second surfactant, which is preferably a polymerizable surfactant; 9) optionally adding a polyType: ApplicationFiled: October 24, 2006Publication date: July 26, 2007Inventors: Gil Lee, Hao Shang, Won-Suk Chang
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Publication number: 20060275757Abstract: Biological material in a sample is reacted with a novel functionalized superparamagnetic Fe/Au nanoparticle that specifically binds to the biological material in solution to produce a magnetic particle/biological material complex. The biological material is detected upon application of an external magnetic field which separates the magnetic bound complex from other components of the reaction mixture.Type: ApplicationFiled: June 30, 2003Publication date: December 7, 2006Inventors: Gil Lee, Ronald Andres
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Publication number: 20060150840Abstract: The present invention discloses a digital textile printer including a front and a rear feeding devices driven by a transfer axis within a driving panel of the front and the rear of a base to prevent distortion and wrinkle phenomena generating defective printing to perform effectively the textile printing even to the very thin textile fabrics, an ink-retrieving hole along to the transfer axis on the top of thee base to collect the residues of the injected ink passing through a printing material to prevent ink from spreading at the printing material, at least one suction pan in the inside of the base to collect easily the residues of the injected ink to hasten dries of ink, and a heater of rubber material in the inside of the front of the base to hasten dries of the printing material passing through the ink-retrieving hole.Type: ApplicationFiled: August 18, 2004Publication date: July 13, 2006Inventor: Gil Lee
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Publication number: 20060043812Abstract: A PMA (Permanent Magnet Assisted) synRM and a method for imposing a magnetic force thereon. Magnets are inserted into outer flux barriers of a plurality of flux barriers formed along the radius of a rotor, and bridges or slim portions are formed on inner flux barriers at positions corresponding to the positions of the magnets so that the magnetic force is imposed on the magnets through coils. Since the number of the flux barriers is sufficiently increased while the amount of the magnets consumed is decreased, the PMA synRM has increased efficiency and reduced production costs.Type: ApplicationFiled: January 4, 2005Publication date: March 2, 2006Applicant: LG Electronics Inc.Inventors: Dal Cheong, Kyung Lee, Hyun Shin, June Won, Jae Oh, Gil Lee
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Publication number: 20060033457Abstract: A sensorless motor drive apparatus and a method for protecting and controlling the same. The sensorless motor drive apparatus includes a unit for determining the presence or absence of a position estimation error of a rotor contained in a motor using a current value applied to the motor and a position estimation angle of the rotor. Therefore, the sensorless motor drive apparatus determines the presence or absence of the position estimation error of the rotor without using a sensor, so that it reduces production costs, prevents the motor from generating a faulty operation, and prevents a compressor including the motor from being damaged.Type: ApplicationFiled: January 19, 2005Publication date: February 16, 2006Applicant: LG Electronics Inc.Inventors: June Won, Jae Oh, Gil Lee, Dal Cheong