Patents by Inventor Gil Y. Melmed

Gil Y. Melmed has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240024697
    Abstract: The disclosed technology relates to a system for delivering UV-A/B light with a catheter to treat infectious or inflammatory disorders in a patient. While UV light in the UV-C range has traditionally been used to treat skin disorders and for focused ablation of plaques in the arteries and other targeted internal uses, it has not been developed for broader infection, inflammation or neoplasia treatment inside the human body. Here, the inventor(s) developed a system for emission of therapeutic doses of UV light via a catheter, capsule, endoscope, tube or port that can be used to manage internal infections and inflammatory conditions inside a patient.
    Type: Application
    Filed: August 2, 2023
    Publication date: January 25, 2024
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed
  • Publication number: 20230302292
    Abstract: Methods and systems one or more for performing intra-luminal ultraviolet therapy for treating and/or ameliorating a gastrointestinal tract inflammation and/or infection are provided. In one example, a light delivery catheter may include a light emitting portion and non-illuminating portion, wherein the light emitting portion may include one or more UV transparent balloons. In some examples, the UV light source is configured to emit narrow-band light having wavelengths in a range between 335 nm and 349 nm.
    Type: Application
    Filed: August 13, 2021
    Publication date: September 28, 2023
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed
  • Publication number: 20230147752
    Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separating a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space and a cooling tube. In some examples, the UV light source is configured to emit light with wavelengths with a desired intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.
    Type: Application
    Filed: March 19, 2021
    Publication date: May 11, 2023
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite, Konstantin Degtyarev, Larry Bischoff, Kuldeep Gandhi, Michael V. Quinn, Richard Cronenberg
  • Publication number: 20230035292
    Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.
    Type: Application
    Filed: March 14, 2022
    Publication date: February 2, 2023
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite
  • Publication number: 20220260565
    Abstract: Described herein are methods of treatment of an inflammatory condition related to fungal immunity. The present disclosure relates to methods and systems for identifying patients suitable for treatment with active agents, as described herein. Further, described herein are various compositions for treating and identifying a subject in need of an active agent for treatment.
    Type: Application
    Filed: September 19, 2019
    Publication date: August 18, 2022
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: David Underhill, Dermot McGovern, Jose Limon, Gil Y. Melmed
  • Patent number: 11318325
    Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.
    Type: Grant
    Filed: October 21, 2021
    Date of Patent: May 3, 2022
    Assignee: Cedars-Sinai Medical Center
    Inventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite
  • Publication number: 20220040497
    Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.
    Type: Application
    Filed: October 21, 2021
    Publication date: February 10, 2022
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite
  • Patent number: 11179575
    Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.
    Type: Grant
    Filed: August 13, 2020
    Date of Patent: November 23, 2021
    Assignee: Cedars-Sinai Medical Center
    Inventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite
  • Publication number: 20210106844
    Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.
    Type: Application
    Filed: August 13, 2020
    Publication date: April 15, 2021
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite
  • Publication number: 20200346032
    Abstract: The disclosed technology relates to a system for delivering UV-A/B light with a catheter to treat infectious or inflammatory disorders in a patient. While UV light in the UV-C range has traditionally been used to treat skin disorders and for focused ablation of plaques in the arteries and other targeted internal uses, it has not been developed for broader infection, inflammation or neoplasia treatment inside the human body. Here, the inventor(s) developed a system for emission of therapeutic doses of UV light via a catheter, capsule, endoscope, tube or port that can be used to manage internal infections and inflammatory conditions inside a patient.
    Type: Application
    Filed: July 15, 2020
    Publication date: November 5, 2020
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed
  • Publication number: 20190175938
    Abstract: The disclosed technology relates to a system for delivering UV-A/B light with a catheter to treat infectious or inflammatory disorders in a patient. While UV light in the UV-C range has traditionally been used to treat skin disorders and for focused ablation of plaques in the arteries and other targeted internal uses, it has not been developed for broader infection, inflammation or neoplasia treatment inside the human body.
    Type: Application
    Filed: May 31, 2017
    Publication date: June 13, 2019
    Applicant: Cedars-Sinai Medical Center
    Inventors: Ali REZAIE, Mark PIMENTEL, Gil Y. MELMED
  • Publication number: 20110160765
    Abstract: This invention relates to methods and devices utilizing minimally invasive techniques for digestive system fistula closure using occluder devices and various securing and sealing means. The present subject matter expands upon the breadth of current endoscopic techniques by implementing novel occluder devices and techniques intended specifically for treatment of digestive fistulas.
    Type: Application
    Filed: April 8, 2009
    Publication date: June 30, 2011
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Gil Y. Melmed, Simon K. Lo, Saibal Kar