Patents by Inventor Gilbert G. Aubard

Gilbert G. Aubard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5266599
    Abstract: (+)-1-[(3,4,5-trimethoxy)-benzyloxymethyl]-1-phenyl-N,N-dimethyl-n-propylam ine of formula ##STR1## is a medicament of use in gastroenterology.
    Type: Grant
    Filed: August 19, 1992
    Date of Patent: November 30, 1993
    Assignee: Jouveinal S.A.
    Inventors: Gilbert G. Aubard, Alain P. Calvet, Agnes Grouhel, Henri Jacobelli, Jean-Louis Junien, Xavier B. Pascaud, Francois J. Roman
  • Patent number: 5245080
    Abstract: (+)-1-[(3,4,5-trimethoxy)-benzyloxymethyl]-1-phenyl-N,N-dimethyl-n-propylam ine of formula ##STR1## is a medicament of use in gastroenterology.
    Type: Grant
    Filed: August 19, 1992
    Date of Patent: September 14, 1993
    Assignee: Jouveinal SA
    Inventors: Gilbert G. Aubard, Alain A. Calvet, Henri Jacobelli, Jean-Louis Junien, Xavier B. Pascaud
  • Patent number: 5089639
    Abstract: N-Cycloalkylalkylamines of formula I: ##STR1## in which: R1 is phenyl which is optionally mono-, di- or trisubstituted by halogens or lower alkyl, haloalkyl or lower alkoxy radicals, or is an aromatic heterocyclic radical having 5 to 7 chain members, in which the hetero atom is nitrogen, oxygen or sulphur,R2 is lower alkyl,R3 is hydrogen or lower alkyl,m has the value of 1 or 2,R4 is cycloalkyl --CH(CH2)n, in which a carbon atom may carry a radical Rx, which is lower alkyl or phenyl; and in which n has the values from 2 to 5,R5 is phenyl, which can be mono-, di- or trisubstituted by halogens or by lower alkoxy radicals, andQ represents an ethylene-1,2-diyl group --CH.dbd.
    Type: Grant
    Filed: January 24, 1991
    Date of Patent: February 18, 1992
    Assignee: Jouveinal S.A.
    Inventors: Gilbert G. Aubard, Alain P. Calvet, Jean-Pierre Defaux, Claude J. Gouret, Agnes M. Grouhel, Henry L. Jacobelli, Jean-Louis Junien, Xavier B. Pascaud, Francois F. Roman, James P. Hudspeth, Yuan Lin
  • Patent number: 5034419
    Abstract: N-Cycloalkylalkylamines of formula I: ##STR1## in which: R1 is phenyl which is optionally mono-, di- or trisubstituted by halogens or lower alkyl, haloalkyl or lower alkoxy radicals, or is an aromatic heterocyclic radical having 5 to 7 chain members, in which the hetero atom is nitrogen, oxygen or sulphur,R2 is lower alkyl,R3 is hydrogen or lower alkyl,m has the value of 1 or 2,R4 is cycloalkyl --CH(CH2)n, in which a carbon atom may carry a radical Rx, which is lower alkyl or phenyl; and in which n has the values from 2 to 5,R5 is phenyl, which can be mono-, di- or trisubstituted by halogens or by lower alkoxy radicals, andQ represents an ethylene-1,2-diyl group --CH.dbd.
    Type: Grant
    Filed: February 26, 1990
    Date of Patent: July 23, 1991
    Assignee: L'Oreal
    Inventors: Gilbert G. Aubard, Alain P. Calvet, Jean-Pierre DeFaux, Claude J. Gouret, Agnes M. Grouhel, Henry L. Jacobelli, Jean-Louis Junien, Xavier Pascaud, Francois F. Roman, James P. Hudspeth, Yuan Lin
  • Patent number: 5021408
    Abstract: 3,20-dione-11.beta.-hydroxypregn-4-ene-21-thioacetate-17-butyrate and 3,20-dione-11.beta.-hydroxypregn-4-ene-21-thiopropionate-17-butyrate, are anti-inflamatory agents.
    Type: Grant
    Filed: July 9, 1987
    Date of Patent: June 4, 1991
    Assignee: Jouveinal S.A.
    Inventors: Gilbert G. Aubard, Agnes G. Grouhel, Jean-Louis Junien, Claude P. Roux, Dieran R. Torossian
  • Patent number: 5017723
    Abstract: Substituted ethylamines of the formula ##STR1## wherein R.sub.1 is phenyl optionally mono-, di- or trisubstituted by halogen, lower alkyl, lower haloalkyl or lower alkoxy, or is an aromatic heterocycle having 5 to 7 chains wherein the heteroatom is nitrogen, oxygen or sulfur,R.sub.2 is lower alkyl,R.sub.3 and R.sub.4, each independently, represent hydrogen, lower alkyl or lower alkenyl,R.sub.5 is phenyl optionally mono-, di- or trisubstituted by halogen or lower alkoxy or is an aromatic heterocycle having 5 to 7 chains wherein the heteroatom is nitrogen, oxygen or sulfur andQ represents a --CH.dbd.CH-- ethylene group or a 1,2-diyl ##STR2## propane group, their acid addition salts and their optically active forms. These substituted ethylamines have psycotropic properties and are useful as medicines.
    Type: Grant
    Filed: February 26, 1990
    Date of Patent: May 21, 1991
    Assignee: Jouveinal S.A.
    Inventors: Gilbert G. Aubard, Alain P. Calvet, Claude J. Gouret, Agnes M. Grouhel, Henry L. Jacobelli, Jean-Louis Junien, Xavier B. Pascaud, Francois J. Roman, Claude D. Soulard, James P. Hudspeth, Yuan Lin
  • Patent number: 4933331
    Abstract: 3,20-dione-11.beta.-hydroxypregn-4-ene-21-thioacetate-17-butyrate and 3,20-dione-11.beta.-hydroxypregn-4-ene-21-thiopropionate-17-butyrate, are anti-inflammatory agents.
    Type: Grant
    Filed: November 4, 1985
    Date of Patent: June 12, 1990
    Assignee: Jouveinal, S.A.
    Inventors: Gilbert G. Aubard, Agnes G. Grouhel, Jean-Louis Junien, Claude P. Roux, Dieran R. Torossian
  • Patent number: 4761400
    Abstract: Lactulose-based laxative composition which is in the form of a jelly with a viscosity at 20.degree. C. measured on the Brookfield viscosimeter between 15,000 and 30,000 centipoises, a refractive index at 20.degree. C. between 1.430 and 1.445 and a pH between 3 and 4.
    Type: Grant
    Filed: January 6, 1986
    Date of Patent: August 2, 1988
    Assignee: Jouveinal S.A.
    Inventors: Bernard J. M. Doat, Jean-Francois J. Letavernier, Gilbert G. Aubard, Jean B. Llull, Alain P. Calvet, Jean-Louis Junien
  • Patent number: 4734428
    Abstract: Aminoethyl imidazole of formula: ##STR1## in which R.sub.1 is a lower alkyl, R.sub.2 is a phenyl or phenoxy radical, optionally substituted by a halogen atom or a lower alkoxy radical, R.sub.3,R.sub.4 and R.sub.5 are a hydrogen atom or a lower alkyl radical and x, y and z have the value 0 or 1, but the values of y and z cannot be the same, together with their acid addition salts with acids.Cytoprotective medicament.
    Type: Grant
    Filed: June 10, 1986
    Date of Patent: March 29, 1988
    Assignee: Jouveinal S.A.
    Inventors: Gilbert G. Aubard, Jacques Bure, Agnes G. Grouhel, Jean-Louis Junien, Veronique J. Lelievre, Xavier B. Pascaud, Claude P. Roux
  • Patent number: 4427671
    Abstract: Compounds of formula: ##STR1## wherein A and B each represent, independently of each other, a straight-chained or branched alkyl group having from 1 to 6 carbon atoms or a phenyl group optionally mono- or polysubstituted by alkyl radicals having from 1 to 6 carbon atoms, alkoxy groups having from 1 to 6 carbon atoms or halogen, T and U, independently of each other, represent hydrogen atoms or together form a double bond, V is a hydrogen atom or a methyl group at the .alpha.-position, W is a hydrogen atom or a halogen atom at the .alpha.-position, X is a hydroxy group at the .beta.-position and Y is a hydrogen atom or X and Y may together represent an oxygen atom, and Z.sub.1 is a hydrogen atom, a methyl group at the .alpha.- or .beta.-position, while Z.sub.2 is a hydrogen atom, or Z.sub.1 and Z.sub.2 together form a methylene group. These compounds have anti-inflammatory activity.
    Type: Grant
    Filed: July 13, 1982
    Date of Patent: January 24, 1984
    Assignee: S.I.P.S.Y.
    Inventors: Dieran R. Torossian, Gilbert G. Aubard, Claude P. Roux, Agnes G. Grouhel
  • Patent number: 4301163
    Abstract: Amino-ether oxides of formula: ##STR1## in which R.sub.1 is lower alkyl, R.sub.2 and R.sub.3 which are the same or different are hydrogen or lower alkyl, R.sub.4 is a phenyl or phenoxy nucleus optionally monosubstituted to trisubstituted by substituents which are the same or different, halogen or lower alkoxy, R.sub.5 is a phenyl radical optionally monosubstituted to trisubstituted by substituents which are the same or different, halogen, lower alkyl, lower alkoxy or nitro, a pyridyl radical or a lower alkyl radical, n is equal to zero, 1 or 2 and p is an integer from 0 to 9, m and q are equal to zero or 1.Local and spasmolytic anaesthetics.
    Type: Grant
    Filed: July 1, 1980
    Date of Patent: November 17, 1981
    Assignee: Societe Industrielle de Produits de Synthese
    Inventors: Dieran R. Torossian, Claude P. Roux, Gilbert G. Aubard
  • Patent number: 4269778
    Abstract: Process for the preparation of steroids.The steroid 21-thioesters are prepared by preparing the corresponding sulphonates in acetonic suspension and by reacting this suspension directly with a thiocarboxylate.Preparation of synthesis intermediates.
    Type: Grant
    Filed: November 20, 1979
    Date of Patent: May 26, 1981
    Assignee: SIPSY
    Inventors: Dieran R. Torossian, Gilbert G. Aubard
  • Patent number: 4177268
    Abstract: The present invention relates a method for the alleviation of inflammation which comprises administering to a host a therapeutically effective amount of a dexamethasone derivative of the formula ##STR1## in which R represents an alkyl radical comprising a number of carbons atoms between 4 and 9 or a para-fluoro-phenyl radical.The product used in this method has a considerable local anti-inflammatory activity.
    Type: Grant
    Filed: January 4, 1977
    Date of Patent: December 4, 1979
    Assignee: Jouveinal S.A.
    Inventors: Dieran R. Torossian, Gilbert G. Aubard, Jacky M. Legeai