Patents by Inventor Gilbert Iverson

Gilbert Iverson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition for inducing humoral anergy to an immunogen comprising a T cell epitope-deficient analog of the immunogen conjugated to a nonimmunogenic valency platform molecule
    Publication number: 20050170436
    Abstract: Conjugates of nonimmunogenic valency platform molecules and analogs of immunogens that possess the specific B cell binding ability of the immunogen but lack T cell epitopes and which, when introduced into individuals, induce humoral anergy to the immunogen are disclosed. Accordingly, these conjugates are useful for treating antibody-mediated pathologies that are caused by foreign or self immunogens.
    Type: Application
    Filed: October 1, 2004
    Publication date: August 4, 2005
    Inventors: Paul Barstad, Gilbert Iverson
  • Therapeutic and diagnostic domain 1 beta2GP1 polypeptides and methods of using same
    Publication number: 20050004351
    Abstract: The present invention provides domain 1 ?2GPI polypeptides, polynucleotides encoding these polypeptides, mimetics of these polypeptides, and methods using domain 1 ?2GPI polypeptides and mimetics. Domain 1 of ?2GPI has been shown to bind to anti-cardiolipin (?2GPI-dependent antiphospholipid) antibodies, which are associated with several pathologies, such as thrombosis and fetal loss. The domain 1 ?2GPI polypeptides may be used to detect ?2GPI-dependent antiphospholipid antibodies in a sample. The invention further provides methods of inducing tolerance using these domain 1 ?2GPI polypeptides.
    Type: Application
    Filed: July 30, 2004
    Publication date: January 6, 2005
    Inventors: David Marquis, Gilbert Iverson, Edward Victoria, David Jones, Matthew Linnik