Abstract: This system comprises a compacted bag, in particular under vacuum, having an appendage into which a spacer device is inserted (2) which forms a pocket (140) separating two facing flexible partition sections from each other (120,121) of which one (121) is adapted to be applied when placed under vacuum against a set of heatable blades with closed outline linked to each other (51, 61) the interior blade (61) being carried by a mobile part (6) of which the end is able to penetrate into the cut pocket (140) with a view to the inflation of the bag with air brought by a channel (600′) through a sterilizing filter (8).

Abstract: A sterile transfer system between a bag and a enclosure suitable for use in the pharmaceutical industry, characterized on the one hand of a first part of a bag having a mouth in the form of a pocket, in which the bottom is constituted by a flexible partition separating the interior spaces of the pocket and the bag and capable of being heat-cut, on the other hand a lock chamber installed at the entrance to the sterile enclosure which includes a fixed part on which the pocket can be mounted, this part presenting a central opening receiving a mobile element constituting the door of the lock chamber, the fixed and mobile parts each being equipped with a heatable blade with closed outline overlapping and joined at their apex in airtight manner when the bag is in the closed state, vacuum outlets being provided for applying the flexible partition by means of suction against the heatable blades and effecting the cutting of it by fusion of the zones which come into contact with the blades.

Abstract: The device comprises a receiving housing for receiving and maintaining the vial, this latter being comprised of a pocket (10) containing the product and a nozzle (11 ) in which is inserted a pump (8) which has a variable volume chamber (8000) controlled by a movable actuating member (85); the device according to the invention comprises a pushing means (42) capable of acting against this actuating member (85) through the wall of the casing so as to displace it in a so-called "forward" direction against a resilient release means, a locking means (46) capable of locking the pushing means (42) in a position in which it maintains the actuating member in a mobile state at the end of the "forward" stroke, and an unlocking control means (52) of said locking means (46).Device for distributing successive and precise doses of a fluid product, in particular medicinal or cosmetic, for instance for the instillation of an eye lotion.

Abstract: There is disclosed a child resistant blister package comprising a conventional blister package having cavities containing unit doses of medication. The blister package is adapted to receive a locking member which is slidably secured to the blister package to effectively prevent children from accessing the medication therein and yet is readily, slidably removed from the blister package by an adult to access medication therefrom.

Abstract: Packaging vial for a liquid product in particular medicinal or cosmetic, manufacturing process and device for use of this vial. The vial includes a flexible casing (1), coupled to a rigid support (2), the casing (1) consisting of a pocket (10) with thin and distortable walls, containing the product and free from air, as well as a tubular nozzle (11) for dispensing the product, to which is coupled the pocket (10), the vial including furthermore a pump for dosing and delivering the product, said pump containing a fixed body inserted into the nozzle (11) and a moveable actuating member which is located inside the casing, but Which can be moved from the outside of the latter thanks to the distortable character of its wall which, proximate the actuating member, has the shape of a bellows.

Abstract: A sterile packaging assembly (100) for dispensing a liquid in drops comprises a main body (101) of plastic material, having a top portion (103) with an outside thread for receiving a screw cap (104), and containing a flow rate restriction system (105) for controlling drop formation. The flow rate restriction system is positioned substantially on the axis of the main body and is held in position by a constricted portion (106) of the top portion (103) of the main body. The invention is particularly applicable to sterile packaging of pharmaceutical substances such as eye drops.

Abstract: A sterile packaging assembly (100) for dispensing a liquid in drops comprises a main body (101) of plastic material, having a top portion (103) with an outside thread for receiving a screw cap (104), the top portion ending in an elongate neck, constituting a dispensing portion which is surmounted by a closure head (110) that can be torn off in order to define a dispensing orifice (111) on first utilization of the packaging assembly. The invention is particularly applicable to sterile packaging of pharmaceutical substances such as eye drops.

Abstract: There is disclosed a child resistant blister package comprising a conventional blister package having cavities containing unit doses of medication. The blister package is adapted to receive a locking member which is slidably secured to the blister package to effectively prevent children from accessing the medication therein and yet is readily, slidably removed from the blister package by an adult to access medication therefrom.

Abstract: A dual chambered vial is equipt with a dislodgeable stopper device between the two chambers, whereby components of a mixture may be maintained in separate chambers until comingling is desired. The stopper is dislodged by means of a plunger activated by depression of flexible walls of one chamber.

Abstract: A packaging and dispensing system provides for separate packaging of two ingredients of which at least one is a liquid and for extemporaneous mixing of the two ingredients at the time of first use. The system comprises a first bottle (2) containing the liquid or solid first ingredient and the neck of which is stoppered by a plug (5, 8). It further comprises a second bottle (9) containing the liquid second ingredient and assembled to the first bottle (2) at its neck. There is also an internal coupling member (11) carried by the second bottle (9) and the end of which is coupled to the plug (8). This coupling is obtained automatically when the two bottles are assembled together. A cap (13)screwed onto the second bottle (9) is coupled to the coupling member (11) so that at the time of first use unscrewing the cap (13) initially displaces the plug (8) and establishes automatically the communication between the two bottles without compromising any sterile conditions that may apply.

Abstract: A multi-compartment container for mixing two or more constituents at the time of use formed by the assembly of a plurality of compartments which can be filled and assembled and sealed in sterile manner then placed in communication in an absolutely sterile manner by the action of a plunger inside the container while being able to be handled from the outside. Teeth on the plunger pierce the seals of the compartments.