Patents by Inventor Gilbert Legeay

Gilbert Legeay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9005960
    Abstract: The present invention relates to a functionalized semi-permeable membrane composed of a porous biocompatible support pretreated so as to increase the surface energy thereof and characterized in that it includes at least two layers, each having a hydrophilic polymer and at least one biological active molecule, and to the use thereof in particular for producing a bioartificial organ.
    Type: Grant
    Filed: May 31, 2011
    Date of Patent: April 14, 2015
    Assignees: Association pour les Transferts de Technologie du Mans, Centre Europeen d'Etude du Diabete
    Inventors: Gilbert Legeay, Séverine Sigrist, Arnaud Coudreuse
  • Publication number: 20130131828
    Abstract: The present invention relates to a functionalized semi-permeable membrane composed of a porous biocompatible support pretreated so as to increase the surface energy thereof and characterized in that it comprises at least two layers, each comprising a hydrophilic polymer and at least one biologically active molecule, and to the use thereof in particular for producing a bioartificial organ.
    Type: Application
    Filed: May 31, 2011
    Publication date: May 23, 2013
    Applicants: Association Pour Les Transferts De Technologie Du Mans, CENTRE EUROPEEN D'ETUDE DU DIABETE
    Inventors: Gilbert Legeay, Séverine Sigrist, Arnaud Coudreuse
  • Patent number: 8038966
    Abstract: The invention relates to a durable hydrophilic non-porous surface-modified polymer composition, to aqueous fluid channels based on said composition, to a microfluidic system comprising said channels, to a method for the production thereof and to a microfluidic chip or cells incorporating said composition.
    Type: Grant
    Filed: May 10, 2005
    Date of Patent: October 18, 2011
    Assignees: Centre National de la Recherche Scientifique, Ecole Normale Superieure de Cachan, Association pour les Transferts de Technologie du Mans
    Inventors: Laurent Griscom, Bruno Le Pioufle, Gilbert Legeay
  • Publication number: 20080260588
    Abstract: The invention relates to a durable hydrophilic non-porous surface-modified polymer composition, to aqueous fluid channels based on said composition, to a microfluidic system comprising said channels, to a method for the production thereof and to a microfluidic chip or cells incorporating said composition.
    Type: Application
    Filed: May 10, 2005
    Publication date: October 23, 2008
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE NORMALE SUPERIEURE DE CACHAN, ASSOCIATION POUR LES TRANSFERTS DE TECHNOLOGIE DU
    Inventors: Laurent Griscom, Bruno Le Pioufle, Gilbert Legeay
  • Publication number: 20080206795
    Abstract: The invention concerns supports or receptacles for solubilized or suspended biological entities whereof the walls are made of plastics surface-treated by an electromagnetic plasma followed by a polymer deposition. It can be in the form of tubes or multiple-well plates. It provides among other things the possibility of storing, transferring and performing reactions in the context of microassays of biological entities, more particularly the prion protein, with enhanced sensitivity.
    Type: Application
    Filed: April 4, 2006
    Publication date: August 28, 2008
    Inventors: Ernst Heinen, Gilbert Legeay, Fabienne Poncin-Epaillard, Willy Zorzi, Benaissa Elmoualij, Veronique Legeais, Eric Rouault
  • Publication number: 20070269793
    Abstract: The invention relates to bioactive boxes for cellular cultures comprising a bilayer which is arranged on the bottom of said boxes and provided with an internal primary layer made of hydroxypropylmethylcellulose, or polyvinyl alcohol (PVA) and an external bioactive layer made of carboxypropylmethylcellulose. Said invention also relates to the use of the inventive boxes for carrying out methods for studying cellular ageing, cellular differentiation and apoptosis, method s for screening anti-ageing molecules, methods for screening antitumoral molecules, methods for in vitro diagnosis of the antitumoral molecule malignancy and consequently methods for in vitro prognosticating tumors or for study methods related to researches on signalling controlling morphology, bioadhesion, cellular proliferation and intercellular communications.
    Type: Application
    Filed: November 26, 2004
    Publication date: November 22, 2007
    Inventors: Marie-Danielle Nagel, Gilbert Legeay
  • Publication number: 20070202136
    Abstract: A method for reducing the contamination properties by micro-organisms of a surface made of a mineral material, the surface having an area of at least 0.1 m2, the method including the following steps: a) application, onto the surface to be treated, of a layer of a solution or of an aqueous suspension of a hydrophilic polymeric material; b) drying the surface processed at the step a), for obtaining a surface covered with a layer of the hydrophilic polymeric material.
    Type: Application
    Filed: March 2, 2005
    Publication date: August 30, 2007
    Inventors: Gilbert Legeay, Tanguy Honore, Marie-Noelle Bellon-Fontaine, Jean-Marie Herry
  • Patent number: 7056726
    Abstract: The invention concerns a semipermeable chamber for encapsulation of cells producing at least a biological substance of interest, characterised in that it consists of a porous polycarbonate biocompatible film modified at the surface by generated polar sites and covered with at least a layer of hydrophilic polymer.
    Type: Grant
    Filed: January 29, 2002
    Date of Patent: June 6, 2006
    Assignees: Association pour les Transferts de Technologies du Mans, Universite Catholique de louvain, Centre Europeen d'Etude du Diabete (CEED)
    Inventors: Gilbert Legeay, Patrick Bertrand, Alain Belcourt, Laurence Kessler
  • Publication number: 20040137063
    Abstract: The invention concerns a semipermeable chamber for encapsulation of cells producing at least a biological substance of interest, characterised in that it consists of a porous polycarbonate biocompatible film modified at the surface by generated polar sites and covered with at least a layer of hydrophilic polymer.
    Type: Application
    Filed: March 1, 2004
    Publication date: July 15, 2004
    Inventors: Gilbert Legeay, Patrick Bertrand, Alain Belcourt, Laurence Kessler
  • Publication number: 20020193885
    Abstract: The present invention relates to the field of prostheses for plastic reconstruction, especially to mammary and muscular prostheses.
    Type: Application
    Filed: March 25, 2002
    Publication date: December 19, 2002
    Applicant: ASSOC. POUR LES TRANSFERTS DE TECHNOLOGIES DU MANS
    Inventors: Gilbert Legeay, Christelle Porcheron