Patents by Inventor Giles Hugo William Sanders
Giles Hugo William Sanders has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230212651Abstract: There is provided a method of detecting the presence of a nucleic acid target sequence in which two oligonucleotides are used to forma three-way junction with the target sequence to allow detection of the target sequence. Alternatively, three oligonucleotides can be used to form a four-way junction with the target sequence to allow detection of the target sequence.Type: ApplicationFiled: July 24, 2020Publication date: July 6, 2023Inventors: Rebecca Louise Howard, Kathrin Herbst, Giles Hugo William Sanders
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Patent number: 11099202Abstract: Prepackaged reagent reservoirs with associated nozzles allow for accurate, repeatable distribution of reagents in various types of reactions, reducing the risk of human error. Series of reservoirs may be arrayed on a sheet or plane for automated manipulation providing a simply format for organizing, storing, transporting, and distributing reagents needed in complex reactions such as those in the molecular biology field.Type: GrantFiled: October 20, 2017Date of Patent: August 24, 2021Assignee: TECAN GENOMICS, INC.Inventors: Douglas A. Amorese, Nitin Sood, Philip John Rawlins, Sebastian Georg Rammensee, Michael Ian Walker, Thomas William Broughton, Michiel Clemens Rene Twisk, Jonathan Patrick Casey, Michael Roy Fairs, Neil Pollock, Nuno Varelas, Giles Hugo William Sanders
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Patent number: 10640745Abstract: The present invention relates to a method for the deformation and/or fragmentation of a cell, spore or virus, the method comprising: (i) bringing a liquid sample containing the cell, spore or virus into contact with a first surface of a vibratable plate having at least one aperture, and causing the plate to vibrate; and (ii) passing the sample of the cell, spore or virus through the at least one aperture in the vibrating plate so as to cause deformation and/or fragmentation of the cell, spore or virus. It also concerns a device for carrying out the method.Type: GrantFiled: May 16, 2014Date of Patent: May 5, 2020Assignee: TTP PLCInventors: Giles Hugo William Sanders, Abi Clair Graham, Rita Stella
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Publication number: 20190120868Abstract: Prepackaged reagent reservoirs with associated nozzles allow for accurate, repeatable distribution of reagents in various types of reactions, reducing the risk of human error. Series of reservoirs may be arrayed on a sheet or plane for automated manipulation providing a simply format for organizing, storing, transporting, and distributing reagents needed in complex reactions such as those in the molecular biology field.Type: ApplicationFiled: October 20, 2017Publication date: April 25, 2019Inventors: Douglas A. Amorese, Nitin Sood, Philip John Rawlins, Sebastian Georg Rammensee, Michael Ian Walker, Thomas William Broughton, Michiel Clemens Rene Twisk, Jonathan Patrick Casey, Michael Roy Fairs, Neil Pollock, Nuno Varelas, Giles Hugo William Sanders
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Patent number: 10093965Abstract: A system for preparing and analyzing a sample of biological material, including a test cartridge having a first housing defining a flow-through chamber, a second housing defining a central space within which the first housing is at least partially located. The first housing is rotatable relative to the second housing, and the second housing defines a plurality of circumferentially spaced chambers, one of the chambers having an inlet for receiving a sample, at least one of the chambers containing a liquid reagent, and at least one of the chambers comprising an analysis module, the chambers of the second housing each having an opening into the central space. The first housing has one or more openings into the central space so that openings can be selectively aligned with one of the openings into the chambers of the second housing by relative rotation of the first housing and second housings.Type: GrantFiled: September 25, 2017Date of Patent: October 9, 2018Assignee: DNA NUDGE LIMITEDInventors: Christofer Toumazou, Stuart Bhimsen Lowe, Steven William Green, Piers Sebastian Harding, Giles Hugo William Sanders, Nicholas James Wooder, Andreas Augustinus Werdich, Michiel Clemens Rene Twisk, Rene Heinz Joaquim Zander, Jonathan Casey, Hannah Victoria Hare, Richard Lintern, Stephanie Weichert, Steven James Wakefield, Kathrin Herbst, Luciano Zanchet
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Publication number: 20180087097Abstract: A system for preparing and analysing a sample of biological material, including a test cartridge having a first housing defining a flow-through chamber, a second housing defining a central space within which the first housing is at least partially located. The first housing is rotatable relative to the second housing, and the second housing defines a plurality of circumferentially spaced chambers, one of the chambers having an inlet for receiving a sample, at least one of the chambers containing a liquid reagent, and at least one of the chambers comprising an analysis module, the chambers of the second housing each having an opening into the central space. The first housing has one or more openings into the central space so that openings can be selectively aligned with one of the openings into the chambers of the second housing by relative rotation of the first housing and second housings.Type: ApplicationFiled: September 25, 2017Publication date: March 29, 2018Inventors: Christofer TOUMAZOU, Stuart Bhimsen LOWE, Steven William GREEN, Piers Sebastian HARDING, Giles Hugo William SANDERS, Nicholas James WOODER, Andreas Augustinus WERDICH
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Publication number: 20160083687Abstract: The present invention relates to a method for the deformation and/or fragmentation of a cell, spore or virus, the method comprising: (i) bringing a liquid sample containing the cell, spore or virus into contact with a first surface of a vibratable plate having at least one aperture, and causing the plate to vibrate; and (ii) passing the sample of the cell, spore or virus through the at least one aperture in the vibrating plate so as to cause deformation and/or fragmentation of the cell, spore or virus. It also concerns a device for carrying out the method.Type: ApplicationFiled: May 16, 2014Publication date: March 24, 2016Applicant: THE TECHNOLOGY PARTNERSHIP PLCInventors: Giles Hugo William Sanders, Abi Clair Graham, Rita Stella
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Patent number: 6979390Abstract: A system for separating biological molecules includes a chip (10) on which there is an electrophoresis separation microchannel (16). At the start of the channel there is an isoelectric focusing section (14) containing a gel having a pH gradient. Molecules to be separated are placed in the focusing section (14) and move to an equilibrium position under the influence of an electric field. The electrophoretic state of the molecules is then changed, and a high voltage potential applied across the entire length of the focusing and separation sections. The molecules migrate under the influence of the electric field from the focusing section into the separation section where their position and velocity are tracked. From a knowledge of position and velocity, a user can determine both charge/mass ratio and isoelectric equilibrium point for each molecule. The gels can be replicated in the chip to allow parallel analysis, and hence comparisons, to take place.Type: GrantFiled: October 23, 2001Date of Patent: December 27, 2005Assignee: Deltadot LimitedInventors: Giles Hugo William Sanders, John Hassard, Stuart Hassard, Dimitrios Sideris
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Publication number: 20040100268Abstract: A system for separating biological molecules includes a chip (10) on which there is an electrophoresis separation microchannel (16). At the start of the channel there is an isoelectric focusing section (14) containing a gel having a pH gradient. Molecules to be separated are placed in the focusing section (14) and move to an equilibrium position under the influence of an electric field. The electrophoretic state of the molecules is then changed, and a high voltage potential applied across the entire length of the focusing and separation sections. The molecules migrate under the influence of the electric field from the focusing section into the separation section where their position and velocity are tracked. From a knowledge of position and velocity, a user can determine both charge/mass ratio and isoelectric equilibrium point for each molecule. The gels can be replicated in the chip to allow parallel analysis, and hence comparisons, to take place.Type: ApplicationFiled: November 17, 2003Publication date: May 27, 2004Inventors: Giles Hugo William Sanders, John Hassard, Stuart Hassard, Dimitrios Sideris