Abstract: An implant for the replacement and regeneration of biological tissue in the shape of a plug, comprising a base section (2) configured for anchoring in bone tissue, a middle section (3) configured for replacing cartilage tissue, and a top section (4) configured for growing cartilage tissue onto and into, wherein the middle and top sections comprise the same thermoplastic elastomeric material, which is porous in the top section, and non-porous in the middle section, and wherein the base section comprises a substantially non-porous polyaryletherketone polymer with a porosity of less than 20%, relative to the total volume of the polyaryletherketone polymer.

Abstract: A non-biodegradable implant for the replacement and regeneration of biological tissue in the shape of a plug, comprising a base section (2) configured for anchoring in bone tissue, a middle section (3) configured for replacing cartilage tissue of an intermediate and deep zone of the cartilage layer and having a thickness of at least 0.

Abstract: A non-biodegradable plug-shaped implant (1) for the replacement and regeneration of biological tissue is described. The implant comprises a base section (2) configured for anchoring in bone tissue, and a top section (4) configured for growing cartilage tissue onto and into. The top section comprises a thermoplastic elastomeric material, which is porous. The thermoplastic elastomeric material comprises a linear block copolymer comprising urethane and urea groups, and may be substantially free of an added peptide compound having cartilage regenerative properties. The base section material further comprises one of a biocompatible metal, ceramic, mineral, such as phosphate mineral, and polymer, optionally a hydrogel polymer, and combinations thereof, wherein the thermoplastic elastomeric material further comprises carbonate groups.