Patents by Inventor Gilles Benichou

Gilles Benichou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Involvement of autoantigens in cardiac graft rejection
    Patent number: 6358751
    Abstract: Allograft rejection is initiated by an immune response to donor major histocompatibility complex proteins. After allogeneic heart transplantation, de novo CD4+ T cell and B cell autoimmune responses to contractile proteins of cardiac muscle, e.g. cardiac myosin (CM), are elicited. The transplantation induced autoimmune response to cardiac myosin plays an significant role in cardiac transplant rejection. Methods are provided for diagnosis and therapy of graft rejection.
    Type: Grant
    Filed: May 12, 1999
    Date of Patent: March 19, 2002
    Assignee: The Regents of the University of California
    Inventors: Gilles Benichou, Eugenia Fedoseyeva