Abstract: This invention relates, in part, to unique and newly identified genetic polynucleotides involved in the process of bone remodeling; variants and derivatives of the polynucleotides and corresponding polypeptides; uses of polynucleotides, polypeptides, variants and derivatives; and methods and compositions for the amelioration of symptoms caused by bone remodeling disorders. Disclosed in particular are, the isolation and identification of polynucleotides, polypeptides, variants and derivatives involved in osteoclast activity, validation of the identified polynucleotides for their potential as therapeutic targets and use of the polynucleotides, polypeptides, variants and derivatives for the amelioration of disease states and research purposes.

Abstract: This invention relates, in part, to unique and newly identified genetic polynucleotides involved in the process of bone remodeling; variants and derivatives of the polynucleotides and corresponding polypeptides; uses of the polynucleotides, polypeptides, variants and derivatives; and methods and compositions for the amelioration of symptoms caused by bone remodeling disorders. Disclosed in particular are, the isolation and identification of polynucleotides, polypeptides, variants and derivatives involved in osteoclast activity, validation of the identified polynucleotides for their potential as therapeutic targets and use of the polynucleotides, polypeptides, variants and derivatives for the amelioration of disease states and research purposes.

Abstract: The present invention relates to polynucleotide and polypeptide sequences which are differentially expressed in cancer cells compared to normal cells. The present invention more particularly relates to the use of these sequences in the diagnosis, prognosis or treatment of cancer and in the detection of cancer cells.

Abstract: This invention relates, in part, to unique and newly identified genetic polynucleotides involved in the process of bone remodeling, variants and derivatives of the polynucleotides and corresponding polypeptides, uses of the polynucleotides, polypeptides, variants and derivatives, and methods and compositions for the amelioration of symptoms caused by bone remodeling disorders. Disclosed in particular are the isolation and identification of polynucleotides polypeptides variants and derivatives involved in osteoclast activity, validation of the identified polynucleotides for their potential as therapeutic targets and use of the polynucleotides, polypeptides, variants and derivatives for the amelioration of disease states and research purposes.

Abstract: This invention relates, in part, to unique and newly identified genetic polynucleotides involved in the process of bone remodeling; variants and derivatives of the polynucleotides and corresponding polypeptides; uses of polynucleotides, polypeptides, variants and derivatives; and methods and compositions for the amelioration of symptoms caused by bone remodeling disorders. Disclosed in particular are, the isolation and identification of polynucleotides, polypeptides, variants and derivatives involved in osteoclast activity, validation of the identified polynucleotides for their potential as therapeutic targets and use of the polynucleotides, polypeptides, variants and derivatives for the amelioration of disease states and research purposes.

Abstract: A monoply pneumatic tire has a reinforced sidewall wherein the reinforcement comprises an extra long turn-up which extends into the belt area of the tire. The tire also has a robust chapex in the bead area of the sidewall which has a shape that results from wrapping the turn-up of the carcass ply around the bead of the tire without an apex. The chapex conforms to the shape of the bead. The material in the chapex corresponds in volume substantially to the combined volume of the apex and the chafer of a similarly sized tire.

Abstract: A training bar (24) to be used by a keyboard user, particularly useful for exercising on a piano. It serves as a support for the wrists and is a reference and a guide for the movement of the hands on the keyboard (20). A smooth bar, parallel to the keyboard, may be adjusted in height and distance by the sides and the final position set to the desired height by a central handle. Two arms (28) are fixed perpendicularly to the smooth bar. A handle (39) allows a U-shaped fixing tube (32) to rotate under the keyboard: the tube has two extensions that connect with the arms, through a joint (50) that permits a rotary movement, allowing to position the smooth bar according to the player's desired height for the exercise to be done, The joint permits the storing of the bar under the keyboard. The fixing tube may be supported by fasteners (34) or by a stand, as a portable option. A pedal may move the handle.

Abstract: The disclosure concerns solid electrolyte capacitors, the anode part of which is formed by etched and oxidated metallic foils. The electrolyte of these capacitors is formed by a material deposited in lacquer form on the metallic foils.

Abstract: A method for the manufacture of an inductive chip of the type with a wire coiled around a core comprises the following steps:(a) Fixing the core to a connecting strip made of a metallic material, the strip being provided with slots by which electrical connections can be obtained on either side of the component,(b) Winding a wire around the fixed core,(c) Soldering each end of the wire to each part of the strip designed to form the electrical connections,(d) Coating the wound core, with the connecting strip acting as a mould joint for the moulding process,(e) Cutting out the connecting strip to set off the limits of each component and the parts intended to form the external electrical connections,(f) Folding and fixing the parts delimited in the previous step of the component.

Abstract: The invention pertains to a capacitor of a thermostable polymer film type. The polymer used is polyphenylquinoxaline or polyhydantoin. The polymer film may be obtained by casting with organic solutions. The capacitor can also be obtained with supporting films covered with metallizations coated with this thermostable polymer.

Abstract: The connecting strip for the manufacture of electric components intended to be used with flow soldering; this connecting strip acts during the entire manufacturing cycle as a support for the base elements of the components and as a joining plane for the molding of the coating resin, the notches punched out in the strip thus limiting the output electrodes of the components as well as the electric connections inside the coating.