Patents by Inventor Gilles Bioley

Gilles Bioley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for affecting infections
    Patent number: 10829542
    Abstract: The invention relates to methods promoting the aggregation of Salmonella bacteria in the gut of subjects, thereby providing immune exclusion and limiting bacterial entry, therefore reducing mucosal and systemic infection.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: November 10, 2020
    Assignees: CSL BEHRING AG, CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS
    Inventors: Blaise Corthésy, Gilles Bioley, Cédric Pierre Vonarburg
  • Gas-filled microvesicles for use as vaccine
    Patent number: 10537622
    Abstract: Gas-filled microvesicles comprising an antigen bound thereto and to aqueous suspensions containing said microvesicles, for use in immunomodulating formulations, in particular as a vaccine. The antigen is covalently bound to a component of the microvesicles envelope. The microvesicles of the invention, comprising a molar excess of fatty acids in the stabilizing envelope, are particularly effective in the uptake by antigen-presenting cells, in particular dendritic cells.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: January 21, 2020
    Assignee: BRACCO SUISSE S.A.
    Inventors: Gilles Bioley, Philippe Bussat, Blaise Corthesy, Anne Lassus
  • METHODS FOR AFFECTING SALMONELLA INFECTIONS
    Publication number: 20190345229
    Abstract: The invention relates to methods promoting the aggregation of Salmonella bacteria in the gut of subjects, thereby providing immune exclusion and limiting bacterial entry, therefore reducing mucosal and systemic infection.
    Type: Application
    Filed: December 20, 2017
    Publication date: November 14, 2019
    Applicants: CSL BEHRING AG, CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS
    Inventors: Blaise CORTHÉSY, Gilles BIOLEY, Cédric Pierre VONARBURG
  • GAS-FILLED MICROVESICLES FOR USE AS VACCINE
    Publication number: 20170348401
    Abstract: Gas-filled microvesicles comprising an antigen bound thereto and to aqueous suspensions containing said microvesicles, for use in immunomodulating formulations, in particular as a vaccine. The antigen is covalently bound to a component of the microvesicles envelope. The microvesicles of the invention, comprising a molar excess of fatty acids in the stabilizing envelope, are particularly effective in the uptake by antigen-presenting cells, in particular dendritic cells.
    Type: Application
    Filed: December 21, 2015
    Publication date: December 7, 2017
    Applicant: BRACCO SUISSE S.A.
    Inventors: Gilles BIOLEY, Philippe BUSSAT, Blaise CORTHESY, Anne LASSUS
  • Methods of using gas-filled microvesicles covalently bound to an antigen
    Patent number: 9770411
    Abstract: Gas-filled microvesicles comprising an antigen bound thereto and to aqueous suspensions containing said microvesicles, for use in immunomodulating formulations, in particular as a vaccine. The antigen is covalently bound to a component of the microvesicles envelope. The microvesicles of the invention are particularly effective in the uptake by antigen-presenting cells, in particular dendritic cells.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: September 26, 2017
    Assignee: Bracco Suisse S.A.
    Inventors: Gilles Bioley, Blaise Corthesy, Philippe Bussat, Anne Lassus, Michel Schneider
  • GAS-FILLED MICROVESICLES FOR USE AS VACCINE
    Publication number: 20130295147
    Abstract: Gas-filled microvesicles comprising an antigen bound thereto and to aqueous suspensions containing said microvesicles, for use in immunomodulating formulations, in particular as a vaccine. The antigen is covalently bound to a component of the microvesicles envelope. The microvesicles of the invention are particularly effective in the uptake by antigen-presenting cells, in particular dendritic cells.
    Type: Application
    Filed: December 21, 2011
    Publication date: November 7, 2013
    Applicant: BRACCO SUISSE S.A.
    Inventors: Gilles Bioley, Blaise CH Corthesy, Philippe Bussat, Anne Lassus, Michel Schneider