Abstract: The computer-implemented fragrance or flavour composition method (300), comprises: a step (305) of defining, upon a computer interface, a value representative of a sustainability impact digital index or of an aggregate sustainability impact digital indicator validity threshold for at least one fragrance or flavour ingredient in the fragrance or flavour composition, said fragrance or flavour ingredient being associated to a fragrance or flavour ingredient digital identifier, or to a fragrance or flavour composition digital identifier, a step (310) of selecting, upon a computer interface, at least one fragrance or flavour ingredient digital identifier, a step (315) of retrieval, by a computing device, from a fragrance or flavour ingredient physical parameter database of a sustainability impact digital index or of an aggregate sustainability impact digital indicator as a function of at least one said fragrance or flavour ingredient digital identifier, a step (320) of comparing, by a computing device, as a fun

Abstract: The present invention relates to the field of organic synthesis and more specifically it concerns a process for preparing a compound of formula (I). Moreover, the present invention comprises also analytical methods of measuring the amount of thiol or thioether compounds having less than 6 carbon atoms in the thiol of formula R—SH and a composition of matter comprising at most 50 ?g/kg of thiol or thioether compounds having less than 6 carbon atoms and at most 1 ppm of any compound of formula (I?).

Abstract: The present disclosure concerns a perfuming ingredient of a compound of formula (I) in the form of any one of its stereoisomers or a mixture thereof, and wherein X represents a CHO group when R1 represents a C1-2 alkyl group or X represents a CH(R6)CHO group when R1 represents a hydrogen atom or a C1-2 alkyl group. Each of R2, R3, R4, R5 and R6 represents, independently from each other, a hydrogen atom or a C1-2 alkyl group; or R3 and R4 represent, when taken together, a ethanediyl group; and —C(R3)(R4)—CH(R5)—OH group is, relative to position 1, an ortho, a meta, a para substituent of the aromatic ring or a mixture thereof. Also disclosed is the compound of formula (I) as part of a perfuming composition or of a perfumed consumer product.

Abstract: The present disclosure concerns a perfuming ingredient of a compound of formula (I) in the form of any one of its stereoisomers or a mixture thereof, and wherein X represents a CHO group when R1 represents a C1-2 alkyl group or X represents a CH(R6)CHO group when R1 represents a hydrogen atom or a C1-2 alkyl group. Each of R2, R3, R4, R5 and R6 represents, independently from each other, a hydrogen atom or a C1-2 alkyl group; or R3 and R4 represent, when taken together, a ethanediyl group; and —C(R3)(R4)—CH(R5)—OH group is, relative to position 1, an ortho, a meta, a para substituent of the aromatic ring or a mixture thereof. Also disclosed is the compound of formula (I) as part of a perfuming composition or of a perfumed consumer product.

Abstract: Provided is a new photochemical process for preparing artemisinin. Also provided are certain dihydroartemisinic acid derivatives useful for preparing artemisinin.

Abstract: Provided is a new photochemical process for preparing artemisinin. Also provided are certain dihydroartemisinic acid derivatives useful for preparing artemisinin.

Abstract: The disclosure relates to a method for preparing a compound of formula (I), wherein P1 and P2 are groups protecting the carboxylic acid and oxyamine functions, starting from pyroglutamic acid (S). The disclosure also relates to novel intermediates.

Abstract: The disclosure relates to a method for preparing a compound of formula (I), wherein P1 and P2 are groups protecting the carboxylic acid and oxyamine functions, starting from pyroglutamic acid (S). The disclosure also relates to novel intermediates.

Abstract: This invention discloses and claims an industrial method for the production of azetidine derivatives, such as, N-(1-benzhydrylazetidin-3-yl)-N-phenylmethylsulphonamide.

Abstract: This invention discloses and claims an industrial method for the production of azetidine derivatives, such as, N-(1-benzhydrylazetidin-3-yl)-N-phenylmethylsulphonamide.

Abstract: Provided is a new photochemical process for preparing artemisinin. Also provided are certain dihydroartemisinic acid derivatives useful for preparing artemisinin.

Abstract: The disclosure relates to a method for preparing a compound of formula (I), wherein P1 and P2 are groups protecting the carboxylic acid and oxyamine functions, starting from pyroglutamic acid (S). The disclosure also relates to novel intermediates.

Abstract: The invention relates to a diastereoselective method for obtaining a primary amine on a steroid, comprising the reduction of an oxime by lithium in ammonia at a low temperature in an ether/alcohol mixture.

Abstract: The present invention provides processes for the preparation of modafinil which includes the step of reacting benzhydrylthiol and chloroacetamide.

Abstract: The present invention provides processes for the preparation of modafinil which includes the step of reacting benzhydrylthiol and chloroacetamide.

Abstract: The present invention provides processes for the preparation of modafinil which includes the step of reacting benzhydrylthiol and chloroacetamide.

Abstract: The present invention provides processes for the preparation of modafinil which includes the step of reacting benzhydrylthiol and chloroacetamide.

Abstract: The present invention relates to a process for preparing 9-deoxo-9(Z)-hydroxyiminoerythromycin A corresponding to formula (I) below: from 9-deoxo-9(E)-hydroxyiminoerythromycin A by reaction with a base in water or in a mixture of water/solvent of dialkyl ketone type capable of forming a crystallizable solvate with the desired 9(Z)-oxime; acidification of the reaction mixture to a pH of between 9 and 11; addition to the said mixture of an organic solvent; optionally concentration under vacuum of the resulting organic phase; and isolation of the desired 9(Z)-erythromycin oxime.

Abstract: The invention relates to a process for preparing compound of general formula I by reductive amination of the corresponding (4″)-carbonyl derivative, characterized in that it comprises: placing the said (4″)-carbonyl derivative in contact with at least one nitrogenous reagent and a Lewis acid under conditions that are favourable for converting the 4″ carbonyl function, reducing the resulting mixture using a reducing agent, and optionally deprotecting the hydroxyl function in position 2′, to give the expected compound of general formula I.

Abstract: The subject-matter of the invention is a process for the stereoselective preparation of a compound of general formula I by stereoselective displacement by a nitrogenous nucleophilic compound of the activated alcohol functional group present at this 4? position in a corresponding derivative of formula II.