Patents by Inventor Gilles-Olivier Gratien

Gilles-Olivier Gratien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing S,S?-dialkyldithiocarbonate from dialkyl disulfide
    Patent number: 11976032
    Abstract: A process for preparing an S,S?-dialkyldithiocarbonate from a dialkyl disulfide and from a particular metal catalyst, in the presence of carbon monoxide is described in addition to the use of S,S?-dialkyldithiocarbonates as reagents for the preparation of polycarbonates, compounds containing at least one urea and/or isocyanate function and compounds containing at least one thioalkyl function.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: May 7, 2024
    Assignee: Arkema France
    Inventors: Paul-Guillaume Schmitt, Georges Frémy, Gilles-Olivier Gratien
  • ANTIFUNGAL PRODRUGS
    Publication number: 20230218652
    Abstract: The invention relates to an antifungal prodrug which comprises an antifungal moiety which is linked to a trigger moiety by means of a self-immolative spacer. The trigger moiety is selected from glycosyl residues and oligosaccharides, stabilizes the self-immolative spacer and is cleavable by a pathogen hydrolytic enzyme which is preferably an extracellular glycosidase (EC 3.2.1). When the trigger moiety is cleaved by the pathogen hydrolytic enzyme, the self-immolative spacer undergoes a spontaneous degradation so as to release the antifungal moiety. The invention also relates to pharmaceutical compositions comprising said prodrug and to its use in the treatment of infectious diseases.
    Type: Application
    Filed: May 28, 2021
    Publication date: July 13, 2023
    Inventors: ARNAUD TESSIER, PATRICE LE PAPE, JACQUES LEBRETON, FABRICE PAGNIEZ, GILLES-OLIVIER GRATIEN
  • PROCESS FOR PREPARING S,S'-DIALKYLDITHIOCARBONATE FROM DIALKYL DISULFIDE
    Publication number: 20230167052
    Abstract: A process for preparing an S,S?-dialkyldithiocarbonate from a dialkyl disulfide and from a particular metal catalyst, in the presence of carbon monoxide is described in addition to the use of S,S?-dialkyldithiocarbonates as reagents for the preparation of polycarbonates, compounds containing at least one urea and/or isocyanate function and compounds containing at least one thioalkyl function.
    Type: Application
    Filed: March 13, 2019
    Publication date: June 1, 2023
    Applicant: Arkema France
    Inventors: Paul-Guillaume Schmitt, Georges Frémy, Gilles-Olivier Gratien