Abstract: In the field of anesthetics, an injectable anesthetic solution having a reduced bitterness including: an anesthetic agent; optionally, a vasoconstrictor; a pharmaceutically acceptable solvent; and a bitterness suppressant including or being a mixture of at least two among sodium saccharin, sorbitol and an amino acid, wherein the amino acid is selected from: serine, threonine and their mixtures. Also, a method for providing the injectable anesthetic solution and its uses in dentistry, oral surgery and/or maxillofacial surgery.

Abstract: Hydraulic cements and hardened materials obtained after hydration of the hydraulic cements, especially cements useful in the medical field such as dental cements. In particular, a hydraulic cement including calcium silicate particles and calcium carbonate particles having specific particles sizes. The hydration of the hydraulic cement enables to provide a hardened composite material with reinforcing properties, having calcium silicate particles dispersed in a solid dispersant phase including calcium silicate hydrates (CSH) and porous intergranular areas including insoluble calcium carbonate particles having a d50 granulometry ranging from 1 nm to 1500 nm.

Abstract: A dental composition including calcium silicate, calcium carbonate, and at least one pozzolanic material, which is useful to prepare a hardened dental material with improved properties. Also, a kit including the dental composition for preparing a hardened dental material, to a medical device including the kit and to the use of the hardened dental material for treating the crown of a tooth and/or the root of a tooth.

Abstract: Hydraulic cements and hardened materials obtained after hydration of the hydraulic cements, especially cements useful in the medical field such as dental cements. In particular, a hydraulic cement including calcium silicate particles and calcium carbonate particles having specific particles sizes. The hydration of the hydraulic cement enables to provide a hardened composite material with reinforcing properties, having calcium silicate particles dispersed in a solid dispersant phase including calcium silicate hydrates (CSH) and porous intergranular areas including insoluble calcium carbonate particles having a d50 granulometry ranging from 1 nm to 1500 nm.

Abstract: A vibration mixer suitable for a cartridge having a longitudinal axis and containing a multi-component material, preferably a two-component material, stored in at least two separated chambers inside the cartridge; the vibration mixer including a cartridge holder and a drive for the cartridge holder; the cartridge holder is configured for receiving and locking only one end of the cartridge and is configured for maintaining the longitudinal axis of the cartridge on the cartridge holder in a vertical position.

Abstract: The dispensing gun, for delivering a material from a cartridge, includes a frame having a handle, an injection gate for connecting a cartridge, the injection gate located at the distal part of the frame, a lever including at least two teeth and a piston with at least two notches. The dispensing gun includes a mechanism for directly locking the cartridge on the injection gate; and the dispensing gun includes a mechanism for pushing the piston inside the cartridge so that the material contained in the cartridge is extruded in a single piston stroke; and the dispensing gun is configured so that the lever includes an actuating state in which the first notch of the piston and the first tooth of the lever are engaged together prior to connecting the cartridge so that the lever and the handle form an angle of almost 90°.

Abstract: Delivery and/or injection systems, preferably for medical applications. Especially, a kit of parts for providing a dental composition able to self-hardening. The kit of parts includes a first waterproof container including an anhydrous calcium silicate phase; and a second container including an aqueous phase. The kit of parts may be used in delivery and/or injection systems so that it delivers a homogenous calcium silicate-based composition having a volume ratio between the calcium silicate phase and the aqueous phase ranging from 1 to 3. Also, the hardened material obtained from the kits of parts, the delivery and/or injection system.

Abstract: Materials for additive manufacturing. More precisely, a non-breaking filament, preferably for 3D printing bone substitutes. The filament includes 50% to 99% in weight to the total weight of the filament (w/w) of a polymeric matrix and 1% to 50% w/w of tricalcium silicate. Also, a method and composition for preparing the filament. Additionally, the uses of the filament, such as for example in the dental field; especially, for providing suitable bone and dental substitutes.

Abstract: A three-dimensional biomaterial including particles encapsulating at least one complement active fragment dispersed therein. Also, a process of manufacturing of the three-dimensional biomaterial with at least one biocompatible and/or resorbable polymer and the particles. The three-dimensional biomaterial is useful for tissue regeneration, especially with regards to dental pulp, dentin, periodontal and gingival tissues, as well as bones tissues.

Abstract: A dental restoration material made from a dental hydraulic cement that includes ultrafine calcium silicate (UCS) particles, in the presence of a limited amount of water, so that the hydraulic cement fast hardens while providing a material having suitable mechanical properties for dental restoration, and especially a high compressive strength.

Abstract: A cartridge for dispensing a material, having: a sleeve having a longitudinal axis and a distal wall with a dispensing hole; a barrel defining a chamber for the material, including a proximal open end and a breakable distal wall at its distal end, and being movable in the sleeve between a first position where its distal wall is a distance from the sleeve's distal wall and a second position where its distal wall's sealing portion contacts an inner surface of the sleeve's distal wall; and a piston having a plate movable to seal the barrel's chamber. The sleeve includes an internal piercing element, near the dispensing hole, for breaking the barrel's distal wall upon moving the barrel from the first to the second position. Around the piercing element is an annular cavity delimited peripherally by a beveled inner surface that complements a beveled outer surface of the barrel.

Abstract: A regenerative material in the connective tissues (such as bone, dentin or pulp) regeneration field. More precisely, a connective tissue regenerative material, preferably a bone, dentin or pulp regenerative material, including: a porous polymer matrix having interconnected pores; and non-hydrated calcium silicate particles; wherein: the polymer matrix is anhydrous; the non-hydrated calcium silicate particles have a d50granulometry, preferably ranging from 0.05 ?m to less than the average diameter size of the pores of the matrix; and the non-hydrated calcium silicate particles being coated on the inside walls of the pores of the matrix. Also, a method for preparing the connective tissue regenerative material and uses of the regenerative materials, such as in the dental field; especially, for providing regenerative materials with improved biomechanical and osteoinductive properties (i.e.

Abstract: According to an aspect of the present disclosure, there is provided a charging system for charging an airtime use account file associated with a user for the provision of mobile telecommunications services to the user. The charging system comprises: one or more data stores configured to store: the airtime use account file, the airtime use account file having an airtime account balance which is debited in correspondence with use of airtime services by the user and has an associated predefined balance threshold; and a dedicated account file associated with the user and configured to store loan funds provided to the user, the dedicated account file having a dedicated account balance which is debited in correspondence with use of payment services or airtime services by the user.

Abstract: A regenerative material in the connective tissues (such as bone, dentin or pulp) regeneration field. More precisely, a connective tissue regenerative material, preferably a bone, dentin or pulp regenerative material, including: a porous polymer matrix having interconnected pores; and non-hydrated calcium silicate particles; wherein: the polymer matrix is anhydrous; the non-hydrated calcium silicate particles have a d50 granulometry, preferably ranging from 0.05 ?m to less than the average diameter size of the pores of the matrix; and the non-hydrated calcium silicate particles being coated on the inside walls of the pores of the matrix. Also, a method for preparing the connective tissue regenerative material and uses of the regenerative materials, such as in the dental field; especially, for providing regenerative materials with improved biomechanical and osteoinductive properties (i.e.

Abstract: The present invention relates to a solid composition comprising: a calcium silicate powder, a set accelerator in the form of a powder, a reinforcing filler in a solid form, a radio-opacifying agent in a solid form, at least one complementary ingredient selected from solid fibers or solid porous fillers, optionally a water-reducing agent in a solid form, and optionally solid pigments. The present invention also relates to a kit of parts for the preparation of a composition suitable for use in dentistry comprising in a first container a solid phase including the solid composition according to the invention, and in a second container an aqueous phase. The present invention also relates to a kit of parts for the preparation of a composition suitable for use in dentistry comprising a container, said container comprising at least two cells, the first cell comprising a solid phase including the solid composition of the invention and the second cell comprising an aqueous phase.

Abstract: The invention relates to a device for centering and clamping conduits which are preferably made from alloy steel and which are positioned end to end in order to be welded to form a pipeline. The invention comprises: means for centering and clamping two conduits that are to be welded, optional leak-tight partition means which define an inerting chamber at the mating surface, and inert gas distribution means for creating a protective atmosphere at the mating surface. The inventive device also comprises at least means for regulating the flow of inert gas and/or the supply pressure of said inert gas as a function of the concentration of O2 measured in the protective atmosphere and/or the pressure measured within said atmosphere, such as to maintain the O2 content of the atmosphere below a pre-determined alarm threshold value and/or the pressure of the atmosphere below a pre-determined threshold value.

Abstract: One subject of the invention is a composition comprising from 5 to 65%, by weight relative to the total weight of the composition, of calcium silicate crystals; from 1 to 20%, by weight relative to the total weight of the composition, of calcium carbonate crystals; in addition from 0 to 50%, preferably from 1 to 40%, by weight relative to the total weight of the composition, of a compound of general formula mCaO.nSiO2.pH2O in which m and n, each independently, vary from 1 to 3 and p varies from 3 to 6; the ratio between the particle size d50 of the calcium silicate crystals and the particle size d50 of the calcium carbonate crystals being less than 10; another subject of the invention is a process for preparing said composition, and also the use of said composition in the dental field.

Abstract: This invention relates to a composition resulting from the mixture of a solid phase, comprising at least one calcium derivative powder in association with at least one radioopacifier and at least one polymer and optionally at least one non-radioopaque filler, all in powder form; and aqueous phase comprising water, at least one water-reducing agent, and at least one set accelerator; the ratio of solid phase to liquid phase ranging from 1.0 to 2.5, preferably from 1.5 to 2.2, more preferably from 2 to 2.15; said composition having a compressive strength of less than 40 MPa, preferably ranging from 1 to 15 MPa, preferably ranging from about 3 to about 12 MPa; this invention also relates to a kit and a method for the manufacture of the composition, and to a method for treating or retreating a canal root.

Abstract: The present invention relates to a solid composition comprising: a calcium silicate powder, a set accelerator in the form of a powder, a reinforcing filler in a solid form, a radio-opacifying agent in a solid form, at least one complementary ingredient selected from solid fibers or solid porous fillers, optionally a water-reducing agent in a solid form, and optionally solid pigments. The present invention also relates to a kit of parts for the preparation of a composition suitable for use in dentistry comprising in a first container a solid phase including the solid composition according to the invention, and in a second container an aqueous phase. The present invention also relates to a kit of parts for the preparation of a composition suitable for use in dentistry comprising a container, said container comprising at least two cells, the first cell comprising a solid phase including the solid composition of the invention and the second cell comprising an aqueous phase.