Abstract: There are provided polypeptides that include an Activin receptor type IIB (ActRIIB) ectodomain (ECD) variant. In some embodiments, a polypeptide of the disclosure includes an ActRIIB-ECD variant fused to an Fc domain moiety. The disclosure also provides pharmaceutical compositions and methods of using the polypeptides to treat diseases and conditions associated with TGF? superfamily ligand signaling, such as pulmonary hypertension, fibrosis, muscle weakness and atrophy, metabolic disorders and/or cardiometabolic disease, bone damage, and/or low red blood cell levels (such as anemia).

Abstract: There are provided tetravalent TGF? receptor-ectodomain based traps having a tailored isoform-specificity profile for neutralization of TGF? ligands, and methods of use thereof in the treatment of diseases and conditions associated with TGF?, particularly TGF?1 and TGF?3. In particular, there are provided TGF? binding agents designed to tailor TGF? isoform specificity, in order to maximize therapeutic efficacy in specific disease indications while minimizing adverse effects. The TGF? binding agents comprise two polypeptides assembled via a multimerization domain, each polypeptide having two TGF?II receptor (TGF?R) ligand-binding domains linked as a doublet, wherein the linkers are selected to tailor isoform specificity.

Abstract: There are provided polypeptides that include an Activin receptor type IIB (ActRIIB) ectodomain (ECD) variant. In some embodiments, a polypeptide of the disclosure includes an ActRIIB-ECD variant fused to an Fc domain moiety. The disclosure also provides pharmaceutical compositions and methods of using the polypeptides to treat diseases and conditions associated with TGF? superfamily ligand signaling, such as pulmonary hypertension, fibrosis, muscle weakness and atrophy, metabolic disorders and/or cardiometabolic disease, bone damage, and/or low red blood cell levels (such as anemia).

Abstract: An active display can be used in a theatre with reduced screen-door effect. For example, the active display can have a structure, such as a diffuser structure, or a diffuser and mask structure, that can have, or appear to have, transmissive areas and opaque areas to reduce the audience from detecting gaps or other non-light sources in the active display. The active display may additionally or alternatively have audio ports to allow sound to pass through the active display and appear to the audience as if the sound is coming from the active display.

Abstract: An active display (102) can be used in a theatre environment (100) in which content to be displayed by the active display (102) can be delivered wirelessly using emitters (118). The active display (102) can include tiles (104a-104d) with detectors (106a-106d) that can detect the wireless signals. The active display (102) can include circuitry that can interpret instructions from the wireless signals for controlling the output (108a-108d) of pixels on the tiles.

Abstract: Screen vibration systems are provided that can vibrate theatre screens while reducing the presence of image artifacts that may otherwise be visible as result of vibrating the screen. In one example of a screen vibration system, the system includes a screen, a permanent magnet mounted to the screen, and a magnetic source positioned with respect to the permanent magnet. The screen is moveable in response to a changing magnetic field from the magnetic source.

Abstract: An active display (102) can be used in a theatre environment (100) in which content to be displayed by the active display (102) can be delivered wirelessly using emitters (118). The active display (102) can include tiles (104a-104d) with detectors (106a-106d) that can detect the wireless signals. The active display (102) can include circuitry that can interpret instructions from the wireless signals for controlling the output (108a-108d) of pixels on the tiles.

Abstract: A cinema screen can be vibrated by a screen vibrator assembly. A screen vibrator assembly can include a vibrator, a mount bracket, and an isolation device. The vibrator can be positioned to generate a vibration for vibrating a cinema screen. The mount bracket is configured to be coupled to a screen support structure of the cinema screen. The isolation device is configured to couple the vibrator to the mount bracket to isolate the mount bracket from the vibration.

Abstract: A cinema screen can be vibrated by a screen vibrator assembly. A screen vibrator assembly can include a vibrator, a mount bracket, and an isolation device. The vibrator can be positioned to generate a vibration for vibrating a cinema screen. The mount bracket is configured to be coupled to a screen support structure of the cinema screen. The isolation device is configured to couple the vibrator to the mount bracket to isolate the mount bracket from the vibration.

Abstract: Screen vibration systems are provided that can vibrate theatre screens using acoustical, electromagnetic, or another type of energy while reducing the presence of image artifacts that may otherwise be visible as result of vibrating the screen. In one example of a screen vibration system, the system includes a screen, a permanent magnet mounted to the screen, and a magnetic source positioned with respect to the permanent magnet and uncoupled from the screen. The screen is moveable in response to a changing magnetic field from the magnetic source.

Abstract: A screen can be vibrated by vibrators that are drivable by signals. Each vibrator can be adjacent in position to other vibrators that are drivable by different types of drive signals than a drive signal associated with the vibrator. The number of drive signals can be equal to or less than the number of vibrators. A vibrator assembly for a vibrator can include a baffle and a transducer that couples to the baffle. The transducer can vibrate at least a portion of the screen. The vibrating screen can be monitored by a sensor and an analyzer unit that can analyze image speckle and screen displacement artifacts in captured images of images projected onto the screen and output results of the analysis.

Abstract: An active display can be used in a theatre with reduced screen-door effect. For example, the active display can have a structure, such as a diffuser structure, or a diffuser and mask structure, that can have, or appear to have, transmissive areas and opaque areas to reduce the audience from detecting gaps or other non-light sources in the active display. The active display may additionally or alternatively have audio ports to allow sound to pass through the active display and appear to the audience as if the sound is coming from the active display.

Abstract: Screen vibration systems are provided that can vibrate theatre screens while reducing the presence of image artifacts that may otherwise be visible as result of vibrating the screen. In one example of a screen vibration system, the system includes a screen, a permanent magnet mounted to the screen, and a magnetic source positioned with respect to the permanent magnet. The screen is moveable in response to a changing magnetic field from the magnetic source.

Abstract: A loudspeaker cabinet having at least one side wall defining a side wall perimeter; a front wall mounted to the at least one side wall along the side wall perimeter, the front wall having a front surface; wherein a central area of the front surface is positioned within the side wall perimeter, an extended area of the front surface extends beyond the side wall perimeter, and a portion of the extended area is configured to provide a gradual transition to open free space.

Abstract: Screen vibration systems are provided that can vibrate theatre screens using acoustical, electromagnetic, or another type of energy while reducing the presence of image artifacts that may otherwise be visible as result of vibrating the screen. In one example of a screen vibration system, the system includes a screen, a permanent magnet mounted to the screen, and a magnetic source positioned with respect to the permanent magnet and uncoupled from the screen. The screen is moveable in response to a changing magnetic field from the magnetic source.

Abstract: Screen vibration systems are provided that can vibrate theater screens using acoustical, electromagnetic, or another type of energy while reducing the presence of image artifacts that may otherwise be visible as result of vibrating the screen. In one example of a screen vibration system, the system includes a screen, a permanent magnet mounted to the screen, and a magnetic source positioned with respect to the permanent magnet and uncoupled from the screen. The screen is moveable in response to a changing magnetic field from the magnetic source.

Abstract: A screen can be vibrated by vibrators that are drivable by signals. Each vibrator can be adjacent in position to other vibrators that are drivable by different types of drive signals than a drive signal associated with the vibrator. The number of drive signals can be equal to or less than the number of vibrators. A vibrator assembly for a vibrator can include a baffle and a transducer that couples to the baffle. The transducer can vibrate at least a portion of the screen. The vibrating screen can be monitored by a sensor and an analyzer unit that can analyze image speckle and screen displacement artifacts in captured images of images projected onto the screen and output results of the analysis.

Abstract: Screen vibration systems are provided that can vibrate theater screens using acoustical, electromagnetic, or another type of energy while reducing the presence of image artifacts that may otherwise be visible as result of vibrating the screen. In one example of a screen vibration system, the system includes a screen, a permanent magnet mounted to the screen, and a magnetic source positioned with respect to the permanent magnet and uncoupled from the screen. The screen is moveable in response to a changing magnetic field from the magnetic source.

Abstract: There is described a method for determining single cell current efficiency in an electrolyzer, the method comprising: measuring voltage of a plurality of single cells in the electrolyzer; measuring electrolyzer current feeding the single cells; detecting one of a shutdown period and a start-up period; and for each single cell: determining a time t taken for a voltage level to reach a predetermined occurrence in a voltage curve after a polarization current has been triggered; and calculating cell current efficiency as a function of the time t.

Abstract: Screen vibration systems are provided that can vibrate theatre screens using acoustical, electromagnetic, or another type of energy while reducing the presence of image artifacts that may otherwise be visible as result of vibrating the screen. In one example of a screen vibration system, the system includes a screen, a permanent magnet mounted to the screen, and a magnetic source positioned with respect to the permanent magnet and uncoupled from the screen. The screen is moveable in response to a changing magnetic field from the magnetic source.