Patents by Inventor Gillian CARLETON

Gillian CARLETON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for enhanced lymphocyte-mediated immunotherapy
    Patent number: 12582699
    Abstract: Lymphocytes having a suppressed autophagy gene useful in immunotherapy are disclosed. The lymphocytes can express an antigen targeting receptor such as a chimeric antigen receptor (CAR) or endogenous or engineered T-cell receptor to target cells expressing a tumor-specific antigen. Methods of making and using such lymphocytes are disclosed. Some such lymphocytes are useful in conducting CAR-T or TCR-T therapy.
    Type: Grant
    Filed: February 12, 2020
    Date of Patent: March 24, 2026
    Assignees: Provincial Health Services Authority, Université Laval
    Inventors: Julian J. Lum, Lindsay Devorkin, Yannick Doyon, Gillian Carleton
  • COMPOSITIONS AND METHODS FOR ENHANCED LYMPHOCYTE-MEDIATED IMMUNOTHERAPY
    Publication number: 20220133793
    Abstract: Lymphocytes having a suppressed autophagy gene useful in immunotherapy are disclosed. The lymphocytes can express an antigen targeting receptor such as a chimeric antigen receptor (CAR) or endogenous or engineered T-cell receptor to target cells expressing a tumor-specific antigen. Methods of making and using such lymphocytes are disclosed. Some such lymphocytes are useful in conducting CAR-T or TCR-T therapy.
    Type: Application
    Filed: February 12, 2020
    Publication date: May 5, 2022
    Inventors: Julian J. LUM, Lindsay DEVORKIN, Yannick DOYON, Gillian CARLETON