Patents by Inventor Gillian Douce

Gillian Douce has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Clostridium difficile toxin-based vaccine
    Patent number: 9694063
    Abstract: The present invention relates to recombinant fragments of C. difficile TcdA and TcdB that may be used in the development of vaccines against C. difficile associated disease. More particularly it relates to combinations comprising a ToxB-GT antigen and a TcdA antigen or a ToxA-GT antigen and a TcdB antigen.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: July 4, 2017
    Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Maria Scarselli, Mariagrazia Pizza, Rosanna Leuzzi, Maria Arico, Manuele Martinelli, Gillian Douce
  • Adjuvant compounds
    Patent number: 9370557
    Abstract: The invention relates to the use of bacterial cytolysin proteins, such as pneumolysin, as adjuvants for stimulating or enhancing immune responses against co-administered target antigens. Desirably, the target antigen is provided as a fusion protein with the cytolysin. The inventors have found that cytolysins may be particularly effective for stimulation of mucosal immune responses against the target antigen.
    Type: Grant
    Filed: June 15, 2007
    Date of Patent: June 21, 2016
    Assignee: The University Court of the University of Glasgow
    Inventors: Timothy John Mitchell, Lea-Ann Kirkham, Graeme James Cowan, Gillian Douce
  • CLOSTRIDIUM DIFFICILE TOXIN-BASED VACCINE
    Publication number: 20150132333
    Abstract: The present invention relates to recombinant fragments of C. difficile TcdA and TcdB that may be used in the development of vaccines against C. difficile associated disease. More particularly it relates to combinations comprising a ToxB-GT antigen and a TcdA antigen or a ToxA-GT antigen and a TcdB antigen.
    Type: Application
    Filed: December 7, 2012
    Publication date: May 14, 2015
    Inventors: Maria Scarselli, Mariagrazia Pizza, Rosanna Leuzzi, Maria Arico, Manuele Martinelli, Gillian Douce
  • Novel Adjuvant Compounds
    Publication number: 20100166795
    Abstract: The invention relates to the use of bacterial cytolysin proteins, such as pneumolysin, as adjuvants for stimulating or enhancing immune responses against co-administered target antigens. Desirably, the target antigen is provided as a fusion protein with the cytolysin. The inventors have found that cytolysins may be particularly effective for stimulation of mucosal immune responses against the target antigen.
    Type: Application
    Filed: June 15, 2007
    Publication date: July 1, 2010
    Inventors: Timothy John Mitchell, Lea-Ann Kirkham, Graeme James Cowan, Gillian Douce