Patents by Inventor Gillian E. Smith

Gillian E. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Materials and methods for prevention or reduction of the severity of heartwater
    Patent number: 6342230
    Abstract: The present invention pertains to materials and methods for preventing, or reducing the severity of, heartwater disease in animals. One aspect of the invention is a vaccine against heartwater comprising cultured inactivated Cowdria ruminantium rickettsiae mixed with a suitable adjuvant. The vaccine of the subject invention can be injected into an animal and, once injected, induces immune responses which protect the animal from severe heartwater when exposed to infection with Cowdria ruminantium rickettsiae. The invention further concerns methods of producing a vaccine for use against heartwater. The invention also concerns methods for inducing an immune response in animals, such as mammals, against heartwater by inoculating an animal with a vaccine composition of the present invention.
    Type: Grant
    Filed: December 17, 1999
    Date of Patent: January 29, 2002
    Assignee: University of Florida
    Inventors: Suman M. Mahan, Anthony F. Barbet, Michael J. Burridge, Gillian E. Smith
  • MATERIALS AND METHODS FOR PREVENTION OR REDUCTION OF THE SEVERITY OF HEARTWATER
    Publication number: 20020004051
    Abstract: The present invention pertains to materials and methods for preventing, or reducing the severity of, heartwater disease in animals. One aspect of the invention is a vaccine against heartwater comprising cultured inactivated Cowdria ruminantium rickettsiae mixed with a suitable adjuvant. The vaccine of the subject invention can be injected into an animal and, once injected, induces immune responses which protect the animal from severe heartwater when exposed to infection with Cowdria ruminantium rickettsiae. The invention further concerns methods of producing a vaccine for use against heartwater. The invention also concerns methods for inducing an immune response in animals, such as mammals, against heartwater by inoculating an animal with a vaccine composition of the present invention.
    Type: Application
    Filed: December 17, 1999
    Publication date: January 10, 2002
    Inventors: SUMAN M. MAHAN, ANTHONY F. BARBET, MICHAEL J. BURRIDGE, GILLIAN E. SMITH
  • Process for preparing aryl-substituted piperidines
    Patent number: 5039803
    Abstract: A process for preparing a compound of formula (I): ##STR1## in which Ar represents an aryl or substituted aryl group and R.sup.3 represents an alkyl group, which comprises reducing a compound of formula (II): ##STR2## in which Ar and R.sup.3 are as defined for formula (I), and Hal represents a halogen atom.
    Type: Grant
    Filed: October 19, 1989
    Date of Patent: August 13, 1991
    Assignee: Beecham Pharmaceuticals
    Inventors: Paul Smith, Gillian E. Smith