Patents by Inventor Gillian Nicholas

Gillian Nicholas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of acyl glucosaminyl inositol amidase and methods of use
    Patent number: 7642280
    Abstract: The present invention provides compounds with activity as inhibitors of acyl glucosaminylinositol amidases with amidase activity against S-conjugate amides, particularly mycothiol-derived S-conjugate amides. Certain of the invention compounds are naturally occurring compounds obtained from marine sponges and other organisms. The invention further provides methods for using the compounds to inhibit virulence and reduce antibiotic resistance of mycothiol-producing bacteria.
    Type: Grant
    Filed: April 8, 2002
    Date of Patent: January 5, 2010
    Assignees: The Regents of the University of California, National Institutes of Health
    Inventors: Robert C. Fahey, Gerald L. Newton, Carole A. Bewley, Gillian Nicholas
  • Inhibitors of acyl glucosaminyl inositol amidase and methods of use
    Publication number: 20040167331
    Abstract: The present invention provides compounds with activity as inhibitors of acyl glucosaminylinositol amidases with amidase activity against S-conjugate amides, particularly mycothiol-derived S-conjugate amides. Certain of the invention compounds are naturally occurring compounds obtained from marine sponges and other organisms. The invention further provides methods for using the compounds to inhibit virulence and reduce antibiotic resistance of mycothiol-producing bacteria.
    Type: Application
    Filed: March 15, 2004
    Publication date: August 26, 2004
    Inventors: Robert C Fahey, Gerald L Newton, Carole A Bewley, Gillian Nicholas