Abstract: The present invention relates to a biocompatible and thermosensitive poly(ethylene glycol)/polyester block copolymer and a method of its preparation thereof, and particularly to a multi-functional intelligent hydrogel polymer comprising a hydrophilic part of a poly(ethylene glycol) (PEG) having a low molecular weight and a hydrophobic part comprising an ester-based caprolactone (CL) segment as an essential ingredient and further comprising a para-dioxanone (PDO) segment, a trimethylene carbonate (TMC) segment or a PDO/TMC copolymer containing the PDO and the TMC segments in a predetermined ratio, which easily forms a desired-shaped gel and decomposes or disperses without necessitating the operation process for removing the gel due to the temperature-dependent phase transition caused by the coagulation and the expansion of polymer micelles comprising a hydrophilic part and a hydrophobic part, thus being applicable to a drug delivery system or a porous support for tissue engineering purpose.

Abstract: A vascular graft fabricated of a polyester fiber, the surface of which is impregnated with biodegradable blood-compatible materials, characterized in that the surface of the said vascular graft comprises carboxylate groups and is impregnated with polysaccharides or their derivatives. The vascular graft is manufactured by treating the hydrophobic surface of a vascular graft fabricated of a polyester fiber to render it more hydrophilic and then impregnating the vascular graft with above polysaccharides or their derivatives by chelate bond with metal ions or physical adsorption in order to increase the adhesion properties and adding glycerin to the impregnated polysaccharides or their derivatives in order to increase the softness so that the impregnated substances may turn into the state of gel by blood at the time of use.