Abstract: A method of generating a report presenting subject-specific information relevant to a treatment of a neuropsychiatric disorder includes obtaining a set of genetic test results. The set of genetic test results includes allelic information for each gene in a set of genomic loci. The method includes obtaining a set of medications including a first medication and obtaining a first patient-specific evaluation associated with the first medication using the set of genetic test results. The method includes determining a set of alternative medications to the first medication and determining, for each respective alternative medication of the set of alternative medications, a corresponding alternative pharmacokinetic and pharmacodynamic patient-specific evaluation using the set of genetic test results.